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Biology of RANK, RANKL, and osteoprotegerin

Arthritis research & therapy, 2007-01, Vol.9 Suppl 1 (Suppl 1), p.S1-S1

2007

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Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts

Journal of bone and mineral research, 2013-04, Vol.28 (4), p.711-722

Boyce, Brendan F

2013

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Functions of RANKL/RANK/OPG in bone modeling and remodeling

Archives of biochemistry and biophysics, 2008-05, Vol.473 (2), p.139-146

2008

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Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice

The Journal of clinical investigation, 2022-04, Vol.132 (8), p.1-17

2022

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B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation

Nature communications, 2018-12, Vol.9 (1), p.5127-14, Article 5127

2018

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Proteasome inhibition-enhanced fracture repair is associated with increased mesenchymal progenitor cells in mice

PloS one, 2022-02, Vol.17 (2), p.e0263839-e0263839

2022

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RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors

The Journal of biological chemistry, 2017-06, Vol.292 (24), p.10169-10179

2017

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NF-κB-Mediated Regulation of Osteoclastogenesis

Endocrinology and Metabolism, 2015, 30(1), , pp.35-44

2015

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TGFβ priming promotes TNF-induced bone erosion: a promising new target in RA?

Nature reviews. Rheumatology, 2022-11, Vol.18 (11), p.617-618

2022

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NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism

The Journal of clinical investigation, 2009-10, Vol.119 (10), p.3024-3034

2009

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High-Fat Diet Causes Bone Loss in Young Mice by Promoting Osteoclastogenesis Through Alteration of the Bone Marrow Environment

Calcified tissue international, 2015-04, Vol.96 (4), p.313-323

2015

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TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression

PloS one, 2015-08, Vol.10 (8), p.e0135728-e0135728

2015

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Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

The Journal of clinical investigation, 2014-01, Vol.124 (1), p.297-310

2014

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TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis

Nature communications, 2019-06, Vol.10 (1), p.2795-15, Article 2795

2019

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Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption

Frontiers in immunology, 2018-09, Vol.9, p.2263-2263

2018

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RANKL-Based Osteoclastogenic Assay from Murine Bone Marrow Cells

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2230, p.457

2021

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Targeting Notch‐Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis

Journal of bone and mineral research, 2017-07, Vol.32 (7), p.1469-1480

2017

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TNF Receptor‐Associated Factor 6 Mediates TNFα‐Induced Skeletal Muscle Atrophy in Mice During Aging

Journal of bone and mineral research, 2020-08, Vol.35 (8), p.1535-1548

2020

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Dimorphic effects of Notch signaling in bone homeostasis

Nature medicine, 2008-03, Vol.14 (3), p.299-305

2008

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Chimeric antigen receptor dendritic cells targeted delivery of a single tumoricidal factor for cancer immunotherapy

Cancer Immunology, Immunotherapy : CII, 2024-08, Vol.73 (10), p.203, Article 203

2024

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Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration

Journal of bone and mineral research, 2013-09, Vol.28 (9), p.1925-1935

2013

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Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH

The Journal of biological chemistry, 2020-08, Vol.295 (33), p.11764-11775

2020

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Osteoclasts have multiple roles in bone in addition to bone resorption

Critical reviews in eukaryotic gene expression, 2009, Vol.19 (3), p.171

2009

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Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells

Frontiers in endocrinology (Lausanne), 2023-02, Vol.14, p.1090049-1090049

2023

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Biology of RANK, RANKL, and osteoprotegerin

Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts

Functions of RANKL/RANK/OPG in bone modeling and remodeling

Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice

B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation

Proteasome inhibition-enhanced fracture repair is associated with increased mesenchymal progenitor cells in mice

RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors

NF-κB-Mediated Regulation of Osteoclastogenesis

TGFβ priming promotes TNF-induced bone erosion: a promising new target in RA?

NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism

High-Fat Diet Causes Bone Loss in Young Mice by Promoting Osteoclastogenesis Through Alteration of the Bone Marrow Environment

TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression

Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis

Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption

RANKL-Based Osteoclastogenic Assay from Murine Bone Marrow Cells

Targeting Notch‐Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis

TNF Receptor‐Associated Factor 6 Mediates TNFα‐Induced Skeletal Muscle Atrophy in Mice During Aging

Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy"

Dimorphic effects of Notch signaling in bone homeostasis

Chimeric antigen receptor dendritic cells targeted delivery of a single tumoricidal factor for cancer immunotherapy

Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration

Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH

Osteoclasts have multiple roles in bone in addition to bone resorption

Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells

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