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Cytochrome P450 3A4 in vivo ketoconazole competitive inhibition: determination of Ki and dangers associated with high clearance drugs in general

Journal of pharmacy & pharmaceutical sciences, 1999-05, Vol.2 (2), p.47

Boxenbaum, H

1999

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First-Time-in-Human Dose Selection: Allometric Thoughts and Perspectives

Journal of clinical pharmacology, 1995-10, Vol.35 (10), p.957-966

1995

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Pharmacokinetics tricks and traps: flip-flop models

Journal of pharmacy & pharmaceutical sciences, 1998-09, Vol.1 (3), p.90-91

Boxenbaum, H

1998

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Effective Half-Life in Clinical Pharmacology

Journal of clinical pharmacology, 1995-08, Vol.35 (8), p.763-766

1995

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Human in vivo competitive inhibition of P450 substrates: increased plasma concentrations as a function of hepatic extraction ratio and percent inhibition

Journal of pharmacy & pharmaceutical sciences, 1999-09, Vol.2 (3), p.89-91

Boxenbaum, H

1999

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Commentary: does caloric restriction induce hormesis?

Human & experimental toxicology, 2000-06, Vol.19 (6), p.330-331

Boxenbaum, H

2000

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Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Journal of pharmacokinetics and biopharmaceutics, 1982-04, Vol.10 (2), p.201-227

Boxenbaum, H

1982

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The bioavailability of intranasal and smoked methamphetamine

Clinical pharmacology and therapeutics, 2003-11, Vol.74 (5), p.475-486

2003

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Interspecies pharmacokinetic scaling and the Dedrick plots

American journal of physiology. Regulatory, integrative and comparative physiology, 1983-12, Vol.245 (6), p.768-R775

1983

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Allometric Analysis of Organ Extraction Ratios

Journal of pharmaceutical sciences, 1997-11, Vol.86 (11), p.1319-1320

1997

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Absorption potential and its variants

Pharmaceutical research, 1999-12, Vol.16 (12), p.1893-1893

BOXENBAUM, H

1999

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Pharmacokinetics tricks and traps: drug dosage adjustment in renal failure

Journal of pharmacy & pharmaceutical sciences, 1999-01, Vol.2 (1), p.2-4

1999

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Influence of Gut Microflora on Bioavailability

Drug metabolism reviews, 1979, Vol.9 (2), p.259-279

1979

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Desmethyldiazepam Pharmacokinetics: Studies Following Intravenous and Oral Desmethyldiazepam, Oral Clorazepate, and Intravenous Diazepam

Journal of clinical pharmacology, 1988-09, Vol.28 (9), p.853-859

1988

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Physiological Pharmacokinetic Models: Some Aspects of Theory, Practice and Potential

Toxicology and industrial health, 1988-06, Vol.4 (2), p.151-171

1988

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Interspecies Pharmacokinetic Scaling and the Evolutionary-Comparative Paradigm

Drug metabolism reviews, 1984, Vol.15 (5-6), p.1071-1121

Boxenbaum, Harold

1984

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Pharmacokinetics: Philosophy of Modeling

Drug metabolism reviews, 1992, Vol.24 (1), p.89-120

Boxenbaum, Harold

1992

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The effect of rifaximin on the pharmacokinetics (PK) of single doses of intravenous (IV) and oral (PO) midazolam in healthy volunteers

Clinical pharmacology and therapeutics, 2004-02, Vol.75 (2), p.P66-P66

2004

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The effect of rifaximin on the pharmacokinetics of a single dose of ethinyl estradiol and norgestimate in healthy female volunteers

Clinical pharmacology and therapeutics, 2004-02, Vol.75 (2), p.P96-P96

2004

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Pharmacokinetic interaction of disulfiram and antidepressants

The American journal of psychiatry, 1985-11, Vol.142 (11), p.1373-1374

1985

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Gompertzian mortality derived from competition between cell-types: Congenital, toxicologic and biometric determinants of longevity

Journal of theoretical biology, 1989-09, Vol.140 (2), p.263-278

1989

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Time Concepts in Physics, Biology, and Pharmacokinetics

Journal of pharmaceutical sciences, 1986-11, Vol.75 (11), p.1053-1062

Boxenbaum, Harold

1986

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Estimation of Ki in a competitive enzyme-inhibition model: comparisons among three methods of data analysis

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.756

1999

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Biphasic Mortality Response of Chipmunks in the Wild to Single Doses of Ionizing Radiation: Toxicity and Longevity Hormesis

Drug metabolism reviews, 1990, Vol.22 (2-3), p.269-289

1990

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ABSPLOTS: a LOTUS 123 spreadsheet for calculating and plotting drug absorption rates

Pharmaceutical research, 1988-04, Vol.5 (4), p.247-248

1988

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Cytochrome P450 3A4 in vivo ketoconazole competitive inhibition: determination of Ki and dangers associated with high clearance drugs in general

First-Time-in-Human Dose Selection: Allometric Thoughts and Perspectives

Pharmacokinetics tricks and traps: flip-flop models

Effective Half-Life in Clinical Pharmacology

Human in vivo competitive inhibition of P450 substrates: increased plasma concentrations as a function of hepatic extraction ratio and percent inhibition

Commentary: does caloric restriction induce hormesis?

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

The bioavailability of intranasal and smoked methamphetamine

Interspecies pharmacokinetic scaling and the Dedrick plots

Allometric Analysis of Organ Extraction Ratios

Absorption potential and its variants

Pharmacokinetics tricks and traps: drug dosage adjustment in renal failure

Influence of Gut Microflora on Bioavailability

Desmethyldiazepam Pharmacokinetics: Studies Following Intravenous and Oral Desmethyldiazepam, Oral Clorazepate, and Intravenous Diazepam

Physiological Pharmacokinetic Models: Some Aspects of Theory, Practice and Potential

Interspecies Pharmacokinetic Scaling and the Evolutionary-Comparative Paradigm

Pharmacokinetics: Philosophy of Modeling

The effect of rifaximin on the pharmacokinetics (PK) of single doses of intravenous (IV) and oral (PO) midazolam in healthy volunteers

The effect of rifaximin on the pharmacokinetics of a single dose of ethinyl estradiol and norgestimate in healthy female volunteers

Pharmacokinetic interaction of disulfiram and antidepressants

Gompertzian mortality derived from competition between cell-types: Congenital, toxicologic and biometric determinants of longevity

Time Concepts in Physics, Biology, and Pharmacokinetics

Estimation of Ki in a competitive enzyme-inhibition model: comparisons among three methods of data analysis

Biphasic Mortality Response of Chipmunks in the Wild to Single Doses of Ionizing Radiation: Toxicity and Longevity Hormesis

ABSPLOTS: a LOTUS 123 spreadsheet for calculating and plotting drug absorption rates

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