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Discriminative Stimulus, Reinforcing, Physical Dependence, and Antinociceptive Effects of Oxycodone in Mice, Rats, and Rhesus Monkeys

Experimental and clinical psychopharmacology, 2004-08, Vol.12 (3), p.163-172

2004

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Pharmacological studies with a nonpeptidic, delta-opioid (−)-(1 R,5 R,9 R)-5,9-dimethyl-2′-hydroxy-2-(6-hydroxyhexyl)-6,7-benzomorphan hydrochloride ((−)-NIH 11082)

European journal of pharmacology, 2007-07, Vol.566 (1), p.88-93

2007

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Synthesis and in Vitro and in Vivo Activity of (−)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-Alkenyl-, -N-Alkynyl-, and -N-Cyanoalkyl-5,9-dimethyl-2‘-hydroxy-6,7-benzomorphan Homologues

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.5030-5036

2000

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Etorphines: μ-opioid receptor-selective antinociception and low physical dependence capacity

European journal of pharmacology, 1997-11, Vol.338 (3), p.215-223

1997

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N-(Trifluoromethyl)benzyl substituted N-Normetazocines and N-Norketobemidones

Bioorganic & medicinal chemistry, 2003-01, Vol.11 (1), p.31-33

2003

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Antipodal .alpha.-N-(Methyl through Decyl)-N-normetazocines (5,9.alpha.-Dimethyl-2'-hydroxy-6,7-benzomorphans): In vitro and In vivo Properties

Journal of medicinal chemistry, 1994-09, Vol.37 (20), p.3408-3418

1994

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3-Alkyl Ethers of Clocinnamox: Delayed Long-Term μ-Antagonists with Variable μ Efficacy

Journal of medicinal chemistry, 1998-08, Vol.41 (18), p.3493-3498

1998

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Cocaine, Ecgonine Methyl Ester, and Benzoylecgonine Plasma Profiles in Rhesus Monkeys

Journal of analytical toxicology, 1995-11, Vol.19 (7), p.571-575

1995

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Intracerebellar nicotinic-cholinergic participation in the cerebellar adenosinergic modulation of ethanol-induced motor incoordination in mice

Brain research, 1994-04, Vol.644 (1), p.117-127

1994

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Nicotine's opioid and anti-opioid interactions: Proposed role in smoking behavior

European journal of pharmacology, 1993-12, Vol.248 (4), p.333-335

1993

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Additional Routes in the Metabolism of Nicotine to 3-Pyridylacetate

The Journal of biological chemistry, 1972-02, Vol.247 (3), p.902-908

1972

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The Synthesis of Hydroxycotinine and Studies on Its Structure1

Journal of organic chemistry, 1963-02, Vol.28 (2), p.383-387

1963

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The Isolation and Structure of a Ketoamide Formed in the Metabolism of Nicotine1

Journal of the American Chemical Society, 1960-08, Vol.82 (15), p.3974-3976

1960

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Demethylation of Cotinine in Vivo1

Journal of the American Chemical Society, 1959-08, Vol.81 (15), p.3951-3954

1959

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Metabolism of (±)-Cotinine-2-14C in the Rat1a,2

Journal of medicinal chemistry, 1967-11, Vol.10 (6), p.1033-1036

1967

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Structure of dibromoticonine, a bromination product of nicotine

Journal of the Chemical Society, Perkin Transactions 1, 1973, p.2046

1973

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Metabolism of Nicotine to (+)-γ-(3-Pyridyl)-γ-methylaminobutyric Acid1

Journal of the American Chemical Society, 1958-12, Vol.80 (24), p.6597-6600

1958

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γ-(3-PYRIDYL)-γ-METHYLAMINOBUTYRIC ACID AS A URINARY METABOLITE OF NICOTINE1

Journal of the American Chemical Society, 1957-12, Vol.79 (23), p.6342-6343

1957

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Central behavioral interactions between ethanol, (−)-nicotine, and (−)-cotinine in mice

Brain research bulletin, 1993, Vol.32 (1), p.23-28

1993

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Metabolic Release of Methyl Groups from a Series of N -Methylpyridinium Compounds

Nature (London), 1964-05, Vol.202 (4933), p.699-700

1964

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Demethylation in the Metabolism of (-)-Nicotine in vivo

Nature (London), 1961-06, Vol.190 (4779), p.910-911

1961

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Norcotinine (Desmethylcotinine) as a Urinary Metabolite of Nornicotine

Journal of Medicinal and Pharmaceutical Chemistry, 1961-07, Vol.4 (1), p.21-30

1961

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Urinary Excretion of Conjugate Forms of 1-(3-Pyridyl)ethanol after Administration of 3-Acetylpyridine

The Journal of biological chemistry, 1966-04, Vol.241 (8), p.1878-1881

1966

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The Corrected Structure of a Ketoamide Arising from the Metabolism of (-)-Nicotine

Journal of the American Chemical Society, 1962-12, Vol.84 (23), p.4598-4599

1962

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Tissue disposition of [ 3H]sarin and its metabolites in mice

Toxicology and applied pharmacology, 1986-05, Vol.83 (3), p.412-419

1986

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Discriminative Stimulus, Reinforcing, Physical Dependence, and Antinociceptive Effects of Oxycodone in Mice, Rats, and Rhesus Monkeys

Pharmacological studies with a nonpeptidic, delta-opioid (−)-(1 R,5 R,9 R)-5,9-dimethyl-2′-hydroxy-2-(6-hydroxyhexyl)-6,7-benzomorphan hydrochloride ((−)-NIH 11082)

Synthesis and in Vitro and in Vivo Activity of (−)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-Alkenyl-, -N-Alkynyl-, and -N-Cyanoalkyl-5,9-dimethyl-2‘-hydroxy-6,7-benzomorphan Homologues

Etorphines: μ-opioid receptor-selective antinociception and low physical dependence capacity

N-(Trifluoromethyl)benzyl substituted N-Normetazocines and N-Norketobemidones

Antipodal .alpha.-N-(Methyl through Decyl)-N-normetazocines (5,9.alpha.-Dimethyl-2'-hydroxy-6,7-benzomorphans): In vitro and In vivo Properties

3-Alkyl Ethers of Clocinnamox: Delayed Long-Term μ-Antagonists with Variable μ Efficacy

Cocaine, Ecgonine Methyl Ester, and Benzoylecgonine Plasma Profiles in Rhesus Monkeys

Intracerebellar nicotinic-cholinergic participation in the cerebellar adenosinergic modulation of ethanol-induced motor incoordination in mice

Nicotine's opioid and anti-opioid interactions: Proposed role in smoking behavior

Additional Routes in the Metabolism of Nicotine to 3-Pyridylacetate

The Synthesis of Hydroxycotinine and Studies on Its Structure1

The Isolation and Structure of a Ketoamide Formed in the Metabolism of Nicotine1

Demethylation of Cotinine in Vivo1

Metabolism of (±)-Cotinine-2-14C in the Rat1a,2

Structure of dibromoticonine, a bromination product of nicotine

Metabolism of Nicotine to (+)-γ-(3-Pyridyl)-γ-methylaminobutyric Acid1

γ-(3-PYRIDYL)-γ-METHYLAMINOBUTYRIC ACID AS A URINARY METABOLITE OF NICOTINE1

Central behavioral interactions between ethanol, (−)-nicotine, and (−)-cotinine in mice

Metabolic Release of Methyl Groups from a Series of N -Methylpyridinium Compounds

Demethylation in the Metabolism of (-)-Nicotine in vivo

Norcotinine (Desmethylcotinine) as a Urinary Metabolite of Nornicotine

Urinary Excretion of Conjugate Forms of 1-(3-Pyridyl)ethanol after Administration of 3-Acetylpyridine

The Corrected Structure of a Ketoamide Arising from the Metabolism of (-)-Nicotine

Tissue disposition of [ 3H]sarin and its metabolites in mice

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