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Using fragment-based technologies to target protein-protein interactions

Current pharmaceutical design, 2012, Vol.18 (30), p.4685-4696

2012

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The Directed Ortho Metalation−Ullmann Connection. A New Cu(I)-Catalyzed Variant for the Synthesis of Substituted Diaryl Ethers

Journal of organic chemistry, 1999-04, Vol.64 (9), p.2986-2987

1999

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The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.3895-3899

2012

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Structure-guided design of pyrazolo[1,5- a]pyrimidines as inhibitors of human cyclin-dependent kinase 2

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.863-867

2005

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Diastereoselective oxidation of arylsulfides

Tetrahedron letters, 1994-09, Vol.35 (38), p.7111-7114

1994

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Enantioselective palladium catalysed allylic substitution. Electronic and steric effects of the ligand

Tetrahedron: asymmetry, 1994-10, Vol.5 (10), p.1895-1898

1994

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Synthesis of 2-Substituted Dihydropyran 3-O-Carbamates via Combined Metalation−Suzuki−Miyaura Cross-Coupling Reactions

Journal of organic chemistry, 1998-03, Vol.63 (5), p.1514-1518

1998

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Diastereoselective conversion of sulfides into sulfoxides. 1,5- and 1,6-asymmetric induction

Journal of the Chemical Society, Perkin Transactions 1, 1996-02 (4), p.333

1996

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Intramolecular Anionic Friedel-Crafts Equivalents. A General Regiospecific Route to Substituted and Naturally Occurring Xanthen-9-ones

Synlett, 1997-09, Vol.1997 (9), p.1081-1083

1997

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Catalytic applications of transition metals in organic synthesis

Contemporary organic synthesis, 1996, Vol.3 (4), p.277

1996

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Palladium Catalysed Asymmetric Allylic Substitution. Routes to β-Amino Acids

Synlett, 1996-07, Vol.1996 (7), p.685-686

1996

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Palladium-catalysed asymmetric allylic substitution: synthesis of α- and β-amino acids

Journal of the Chemical Society, Perkin Transactions 1, 1997-05 (9), p.1411-1420

1997

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Stereocontrol with 2-oxazolines

Bower, Justin F

1996

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Stereocontrol with 2-oxazolines

Bower, Justin F

1996

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ChemInform Abstract: The Directed ortho Metalation-Ullmann Connection. A New Cu(I)-Catalyzed Variant for the Synthesis of Substituted Diaryl Ethers

ChemInform, 1999-09, Vol.30 (38), p.no-no

1999

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Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres

Nature (London), 2012-12, Vol.492 (7429), p.423-427

2012

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Observation of absorbing aerosols above clouds over the South-East Atlantic Ocean from the geostationary satellite SEVIRI - Part 2: Comparison with MODIS and aircraft measurements from the CLARIFY-2017 field campaign

Atmospheric chemistry and physics, 2021-03, Vol.21 (4), p.3235-3254

2021

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Evaluating post-wildfire debris-flow rainfall thresholds and volume models at the 2020 Grizzly Creek Fire in Glenwood Canyon, Colorado, USA

Natural hazards and earth system sciences, 2024-06, Vol.24 (6), p.2093-2114

2024

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Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (8), p.2096-2114

2018

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A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma

Cancer research (Chicago, Ill.), 2018-11, Vol.78 (22), p.6509-6522

2018

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Structure-based Drug Design Targeting an Inactive RNA Conformation: Exploiting the Flexibility of HIV-1 TAR RNA

Journal of molecular biology, 2004-02, Vol.336 (3), p.625-638

2004

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Abstract 1933: A novel small molecule inhibitor of MRCK shows utility in blocking radiation induced invasion of glioblastoma cells in vitro and in vivo

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1933-1933

2018

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A novel small-molecule MRCK inhibitor blocks cancer cell invasion

Cell communication and signaling, 2014-10, Vol.12 (1), p.54, Article 54

2014

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Using fragment-based technologies to target protein-protein interactions

The Directed Ortho Metalation−Ullmann Connection. A New Cu(I)-Catalyzed Variant for the Synthesis of Substituted Diaryl Ethers

The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity

Structure-guided design of pyrazolo[1,5- a]pyrimidines as inhibitors of human cyclin-dependent kinase 2

Diastereoselective oxidation of arylsulfides

Enantioselective palladium catalysed allylic substitution. Electronic and steric effects of the ligand

Synthesis of 2-Substituted Dihydropyran 3-O-Carbamates via Combined Metalation−Suzuki−Miyaura Cross-Coupling Reactions

Diastereoselective conversion of sulfides into sulfoxides. 1,5- and 1,6-asymmetric induction

Intramolecular Anionic Friedel-Crafts Equivalents. A General Regiospecific Route to Substituted and Naturally Occurring Xanthen-9-ones

Catalytic applications of transition metals in organic synthesis

Palladium Catalysed Asymmetric Allylic Substitution. Routes to β-Amino Acids

Palladium-catalysed asymmetric allylic substitution: synthesis of α- and β-amino acids

Stereocontrol with 2-oxazolines

Stereocontrol with 2-oxazolines

ChemInform Abstract: The Directed ortho Metalation-Ullmann Connection. A New Cu(I)-Catalyzed Variant for the Synthesis of Substituted Diaryl Ethers

A repeating fast radio burst source localized to a nearby spiral galaxy

Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres

Observation of absorbing aerosols above clouds over the South-East Atlantic Ocean from the geostationary satellite SEVIRI - Part 2: Comparison with MODIS and aircraft measurements from the CLARIFY-2017 field campaign

Evaluating post-wildfire debris-flow rainfall thresholds and volume models at the 2020 Grizzly Creek Fire in Glenwood Canyon, Colorado, USA

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer

A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma

Structure-based Drug Design Targeting an Inactive RNA Conformation: Exploiting the Flexibility of HIV-1 TAR RNA

Abstract 1933: A novel small molecule inhibitor of MRCK shows utility in blocking radiation induced invasion of glioblastoma cells in vitro and in vivo

A novel small-molecule MRCK inhibitor blocks cancer cell invasion

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