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Trojan-Horse Nanotube On-Command Intracellular Drug Delivery

Nano letters, 2012-11, Vol.12 (11), p.5475-5480

2012

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Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons

The Journal of pharmacology and experimental therapeutics, 2009-12, Vol.331 (3), p.1062

2009

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Differential effects of σ1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward

Neuropsychopharmacology (New York, N.Y.), 2007-01, Vol.32 (9), p.1967-1973

2007

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Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation: CONSTITUTIVE ENHANCEMENT OF CALCIUM SIGNALING IN MCF-7 TUMOR CELLS

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28198-28215

2008

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Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity

European journal of pharmacology, 2021-09, Vol.906, p.174263-174263, Article 174263

2021

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Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[ d ]oxazol-2(3 H )-one (SN79) Derivatives

The Journal of pharmacology and experimental therapeutics, 2019-02, Vol.368 (2), p.272

2019

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Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides

Neuropharmacology, 2002-06, Vol.42 (8), p.1043-1055

2002

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Sigma receptors: recent advances and new clinical potentials

Pharmaceutica acta Helvetiae, 2000-03, Vol.74 (2-3), p.211-218

Bowen, Wayne D

2000

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Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity

The Journal of pharmacology and experimental therapeutics, 2015-08, Vol.354 (2), p.203

2015

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Abstract 1279: Sigma-2 receptor-mediated cell death is altered by cell density in human SK-N-SH neuroblastoma 2-D and 3-D cultures

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1279-1279

2016

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Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines

Cancer research (Chicago, Ill.), 2002, Vol.62 (1), p.313-322

2002

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Abstract 3804: Structural changes to SN79 result in ligands that stimulate a metabolic function of sigma-2 receptors

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3804-3804

2016

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Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging

Molecular pharmaceutics, 2017-03, Vol.14 (3), p.770-780

2017

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Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma

The Journal of pharmacology and experimental therapeutics, 2016-02, Vol.356 (2), p.232

2016

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Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting σ1 receptors produce anti-cocaine effects in mice

European journal of pharmacology, 2001-05, Vol.419 (2-3), p.163-174

2001

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Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease

eNeuro, 2020-11, Vol.7 (6), p.ENEURO.0317-20.2020

2020

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Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranes

European journal of pharmacology, 2004-06, Vol.493 (1), p.19-28

2004

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Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells

The Journal of pharmacology and experimental therapeutics, 2000-03, Vol.292 (3), p.900

2000

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σ2 Receptors regulate changes in sphingolipid levels in breast tumor cells

European journal of pharmacology, 2002-05, Vol.443 (1-3), p.207-209

2002

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Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28198-28215

2008

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Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines

Cancer research (Chicago, Ill.), 1995-01, Vol.55 (2), p.408-413

1995

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The sigma1 (σ1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming

Psychopharmacologia, 2004-09, Vol.175 (2), p.154-162

2004

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Haloperidol disrupts Akt signalling to reveal a phosphorylation-dependent regulation of pro-apoptotic Bcl-XS function

Cellular signalling, 2009, Vol.21 (1), p.161-168

2009

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Synthesis and Characterization of [125I]-N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide, a New .sigma. Receptor Radiopharmaceutical: High-Affinity Binding to MCF-7 Breast Tumor Cells

Journal of medicinal chemistry, 1994-06, Vol.37 (12), p.1737-1739

1994

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Targeting sigma receptor-binding benzamides as in vivo diagnostic and therapeutic agents for human prostate tumors

Cancer research (Chicago, Ill.), 1999-09, Vol.59 (18), p.4578-4583

1999

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Trojan-Horse Nanotube On-Command Intracellular Drug Delivery

Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons

Differential effects of σ1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward

Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation: CONSTITUTIVE ENHANCEMENT OF CALCIUM SIGNALING IN MCF-7 TUMOR CELLS

Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity

Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[ d ]oxazol-2(3 H )-one (SN79) Derivatives

Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides

Sigma receptors: recent advances and new clinical potentials

Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity

Abstract 1279: Sigma-2 receptor-mediated cell death is altered by cell density in human SK-N-SH neuroblastoma 2-D and 3-D cultures

Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines

Abstract 3804: Structural changes to SN79 result in ligands that stimulate a metabolic function of sigma-2 receptors

Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging

Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma

Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting σ1 receptors produce anti-cocaine effects in mice

Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease

Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranes

Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells

σ2 Receptors regulate changes in sphingolipid levels in breast tumor cells

Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation

Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines

The sigma1 (σ1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming

Haloperidol disrupts Akt signalling to reveal a phosphorylation-dependent regulation of pro-apoptotic Bcl-XS function

Synthesis and Characterization of [125I]-N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide, a New .sigma. Receptor Radiopharmaceutical: High-Affinity Binding to MCF-7 Breast Tumor Cells

Targeting sigma receptor-binding benzamides as in vivo diagnostic and therapeutic agents for human prostate tumors

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