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New insights into the mechanism of action of acetaminophen: Its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases

Clinical pharmacology and therapeutics, 2006-01, Vol.79 (1), p.9-19

2006

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12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity

Thrombosis and haemostasis, 2013, Vol.110 (3), p.569-581

2013

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Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2 synthases

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (10), p.7130-7135

2002

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Characterization of the Coral Allene Oxide Synthase Active Site with UV−Visible Absorption, Magnetic Circular Dichroism, and Electron Paramagnetic Resonance Spectroscopy: Evidence for Tyrosinate Ligation to the Ferric Enzyme Heme Iron

Biochemistry (Easton), 2001-02, Vol.40 (7), p.2251-2259

2001

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Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site

The Journal of biological chemistry, 2003-04, Vol.278 (16), p.13928-13935

2003

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PGE2 decreases reactivity of human platelets by activating EP2 and EP4

Thrombosis research, 2010-07, Vol.126 (1), p.e23-e29

2010

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Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H 2 synthases

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (10), p.7130-7135

2002

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Characterization of the Lysyl Adducts of Prostaglandin H-Synthases That Are Derived from Oxygenation of Arachidonic Acid

Biochemistry (Easton), 2001-06, Vol.40 (23), p.6948-6955

2001

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Molecular characterization of HDL lipid peroxidation in metabolic syndrome

Free radical biology & medicine, 2012-09, Vol.53, p.S241-S241

2012

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7 FIRST DESCRIPTION: CYTOSOLIC PHOSPHOLIPASE A2-a DEFICIENCY

Journal of investigative medicine, 2006-01, Vol.54 (1), p.S257-S257

2006

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Modification of Proteins by Isoketal-containing Oxidized Phospholipids

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13447-13451

2004

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Prostaglandin H 2 ‐derived adducts of proteins correlate with Alzheimer's disease severity

Journal of neurochemistry, 2005-08, Vol.94 (4), p.1140-1145

2005

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Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis

Organic & biomolecular chemistry, 2009-01, Vol.7 (24), p.5103-5112

2009

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Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes

Methods in molecular biology (Clifton, N.J.), 2010, Vol.644, p.67

2010

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Effects of reactive γ‐ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function

The FASEB journal, 2002-05, Vol.16 (7), p.715-717

2002

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Purification and catalytic activities of the two domains of the allene oxide synthase-lipoxygenase fusion protein of the coral Plexaura homomalla

The Journal of biological chemistry, 1999-11, Vol.274 (47), p.33764-33770

1999

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Formation of highly reactive gamma-ketoaldehydes (neuroketals) as products of the neuroprostane pathway

The Journal of biological chemistry, 2001-08, Vol.276 (33), p.30964-30970

2001

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11,12-Epoxyeicosatrienoic Acid Attenuates Synthesis of Prostaglandin E 2 in Rat Monocytes Stimulated with Lipopolysaccharide

Experimental biology and medicine (Maywood, N.J.), 2003-07, Vol.228 (7), p.786-794

2003

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Cyclooxygenase-2-dependent prostacyclin formation is regulated by low density lipoprotein cholesterol in vitro

Arteriosclerosis, thrombosis, and vascular biology, 2002-06, Vol.22 (6), p.983-988

2002

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Retention of the Label during the Conversion of (3- 3H)Squalene into (3 S)-2,3-Oxidosqualene Catalyzed by Mammalian Squalene Oxidase

Biochemical and biophysical research communications, 1995-03, Vol.208 (1), p.42-47

1995

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Cyclooxygenase-Dependent Lipid-Modification of Brain Proteins

Brain pathology (Zurich, Switzerland), 2005-04, Vol.15 (2), p.139-142

2005

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Identification of a Naturally Occurring Peroxidase-Lipoxygenase Fusion Protein

Science (American Association for the Advancement of Science), 1997-09, Vol.277 (5334), p.1994-1996

1997

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Inhibition of Prostaglandin H 2 Synthases by Salicylate Is Dependent on the Oxidative State of the Enzymes

The Journal of pharmacology and experimental therapeutics, 2003-02, Vol.304 (2), p.589-595

2003

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Characterization of the Lysyl Adducts Formed from Prostaglandin H2 via the Levuglandin Pathway

Biochemistry (Easton), 1999-07, Vol.38 (29), p.9389-9396

1999

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Characterization of the Lysyl Adducts Formed from Prostaglandin H 2 via the Levuglandin Pathway

Biochemistry (Easton), 1999-07, Vol.38 (29), p.9389-9396

1999

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New insights into the mechanism of action of acetaminophen: Its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases

12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2 synthases

Characterization of the Coral Allene Oxide Synthase Active Site with UV−Visible Absorption, Magnetic Circular Dichroism, and Electron Paramagnetic Resonance Spectroscopy: Evidence for Tyrosinate Ligation to the Ferric Enzyme Heme Iron

Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site

PGE2 decreases reactivity of human platelets by activating EP2 and EP4

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H 2 synthases

Characterization of the Lysyl Adducts of Prostaglandin H-Synthases That Are Derived from Oxygenation of Arachidonic Acid

Molecular characterization of HDL lipid peroxidation in metabolic syndrome

7 FIRST DESCRIPTION: CYTOSOLIC PHOSPHOLIPASE A2-a DEFICIENCY

Modification of Proteins by Isoketal-containing Oxidized Phospholipids

Prostaglandin H 2 ‐derived adducts of proteins correlate with Alzheimer's disease severity

Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis

Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes

Effects of reactive γ‐ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function

Purification and catalytic activities of the two domains of the allene oxide synthase-lipoxygenase fusion protein of the coral Plexaura homomalla

Formation of highly reactive gamma-ketoaldehydes (neuroketals) as products of the neuroprostane pathway

11,12-Epoxyeicosatrienoic Acid Attenuates Synthesis of Prostaglandin E 2 in Rat Monocytes Stimulated with Lipopolysaccharide

Cyclooxygenase-2-dependent prostacyclin formation is regulated by low density lipoprotein cholesterol in vitro

Retention of the Label during the Conversion of (3- 3H)Squalene into (3 S)-2,3-Oxidosqualene Catalyzed by Mammalian Squalene Oxidase

Cyclooxygenase-Dependent Lipid-Modification of Brain Proteins

Identification of a Naturally Occurring Peroxidase-Lipoxygenase Fusion Protein

Inhibition of Prostaglandin H 2 Synthases by Salicylate Is Dependent on the Oxidative State of the Enzymes

Characterization of the Lysyl Adducts Formed from Prostaglandin H2 via the Levuglandin Pathway

Characterization of the Lysyl Adducts Formed from Prostaglandin H 2 via the Levuglandin Pathway

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