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Dapagliflozin, a Novel SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects

Clinical pharmacology and therapeutics, 2009-05, Vol.85 (5), p.520-526

2009

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Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus

Diabetes, obesity & metabolism, 2011-04, Vol.13 (4), p.357-365

2011

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Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin

Diabetes, obesity & metabolism, 2013-03, Vol.15 (3), p.280-283

2013

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Pharmacokinetics and pharmacodynamics of dapagliflozin in children and adolescents with type 2 diabetes mellitus

Diabetes, obesity & metabolism, 2016-07, Vol.18 (7), p.678-684

2016

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Comparison of the pharmacokinetics and pharmacodynamics of dapagliflozin in patients with type 1 versus type 2 diabetes mellitus

Diabetes, obesity & metabolism, 2016-03, Vol.18 (3), p.236-240

2016

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Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects

Diabetes, obesity & metabolism, 2011, Vol.13 (1), p.47-54

2011

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Comparison of the exposure-response relationship of dapagliflozin in adult and paediatric patients with type 2 diabetes mellitus

Diabetes, obesity & metabolism, 2016-07, Vol.18 (7), p.685-692

2016

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Evaluation of 4β‐Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism–Based Pharmacometric Model

CPT: pharmacometrics and systems pharmacology, 2014-06, Vol.3 (6), p.1-10

2014

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Time course of muscle sympathetic nerve activity to active muscle during mild isometric contractions in humans

Autonomic neuroscience, 2015-11, Vol.192, p.113-113

2015

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Lack of a pharmacokinetic drug-drug interaction between lithium and valproate when co-administered with aripiprazole

Journal of clinical pharmacy and therapeutics, 2012-10, Vol.37 (5), p.565-570

2012

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The pharmacokinetics of standard antidepressants with aripiprazole as adjunctive therapy: studies in healthy subjects and in patients with major depressive disorder

Journal of psychopharmacology (Oxford), 2010-04, Vol.24 (4), p.537-546

2010

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Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Diabetes, obesity & metabolism, 2011-08, Vol.13 (8), p.770-773

2011

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Fate of the Flavonoid Quercetin in Human Cell Lines: Chemical Instability and Metabolism

Journal of pharmacy and pharmacology, 1999-03, Vol.51 (3), p.353-359

1999

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Effect of St. John's wort ( Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers

Life sciences (1973), 2000-01, Vol.66 (9), p.PL133-PL139

2000

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A Nonlinear Mixed Effects Pharmacokinetic Model for Dapagliflozin and Dapagliflozin 3‐O‐glucuronide in Renal or Hepatic Impairment

CPT: pharmacometrics and systems pharmacology, 2013-05, Vol.2 (5), p.1-9

2013

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Extensive Binding of the Bioflavonoid Quercetin to Human Plasma Proteins

Journal of pharmacy and pharmacology, 1998-02, Vol.50 (2), p.243-249

1998

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Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects

Diabetes, obesity & metabolism, 2011-07, Vol.13 (7), p.604-614

2011

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Effect of saxagliptin on the pharmacokinetics of the active components of Ortho-Cyclen®, a combined oral contraceptive containing ethinyl estradiol and norgestimate, in healthy women

Diabetes, obesity & metabolism, 2012-12, Vol.14 (12), p.1155-1157

2012

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The pharmacokinetics of levosalbutamol : What are the clinical implications?

Clinical pharmacokinetics, 2001, Vol.40 (1), p.23-40

2001

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Enantioselective disposition of salbutamol in man following oral and intravenous administration

British journal of clinical pharmacology, 1996-01, Vol.41 (1), p.35-40

1996

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Pharmacokinetics and pharmacodynamics of methadone enantiomers after a single oral dose of racemate

Clinical pharmacology and therapeutics, 2001-07, Vol.70 (1), p.48-57

2001

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Pharmacokinetics and pharmacodynamics of single oral doses of albuterol and its enantiomers in humans

Clinical pharmacology and therapeutics, 1997-08, Vol.62 (2), p.138-144

1997

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Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity

The Journal of biological chemistry, 1991-01, Vol.266 (1), p.98-103

1991

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Studies on the pharmacokinetics and metabolism of a γ-secretase inhibitor BMS-299897, and exploratory investigation of CYP enzyme induction

Xenobiotica, 2009-07, Vol.39 (7), p.544-555

2009

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Kein Auftreten pharmakokinetischer Wechselwirkungen zwischen Saxagliptin und Dapagliflozin bei gesunden Probanden

Diabetologie und Stoffwechsel, 2016, Vol.11 (S 01)

2016

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Dapagliflozin, a Novel SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects

Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus

Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin

Pharmacokinetics and pharmacodynamics of dapagliflozin in children and adolescents with type 2 diabetes mellitus

Comparison of the pharmacokinetics and pharmacodynamics of dapagliflozin in patients with type 1 versus type 2 diabetes mellitus

Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects

Comparison of the exposure-response relationship of dapagliflozin in adult and paediatric patients with type 2 diabetes mellitus

Evaluation of 4β‐Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism–Based Pharmacometric Model

Time course of muscle sympathetic nerve activity to active muscle during mild isometric contractions in humans

Lack of a pharmacokinetic drug-drug interaction between lithium and valproate when co-administered with aripiprazole

The pharmacokinetics of standard antidepressants with aripiprazole as adjunctive therapy: studies in healthy subjects and in patients with major depressive disorder

Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Fate of the Flavonoid Quercetin in Human Cell Lines: Chemical Instability and Metabolism

Effect of St. John's wort ( Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers

A Nonlinear Mixed Effects Pharmacokinetic Model for Dapagliflozin and Dapagliflozin 3‐O‐glucuronide in Renal or Hepatic Impairment

Extensive Binding of the Bioflavonoid Quercetin to Human Plasma Proteins

Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects

Effect of saxagliptin on the pharmacokinetics of the active components of Ortho-Cyclen®, a combined oral contraceptive containing ethinyl estradiol and norgestimate, in healthy women

The pharmacokinetics of levosalbutamol : What are the clinical implications?

Enantioselective disposition of salbutamol in man following oral and intravenous administration

Pharmacokinetics and pharmacodynamics of methadone enantiomers after a single oral dose of racemate

Pharmacokinetics and pharmacodynamics of single oral doses of albuterol and its enantiomers in humans

Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity

Studies on the pharmacokinetics and metabolism of a γ-secretase inhibitor BMS-299897, and exploratory investigation of CYP enzyme induction

Kein Auftreten pharmakokinetischer Wechselwirkungen zwischen Saxagliptin und Dapagliflozin bei gesunden Probanden

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