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Towards the treatment of polyglutamine diseases: the modulatory role of protein context

Current medicinal chemistry, 2010-09, Vol.17 (27), p.3058

2010

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The Inositol Polyphosphate 5-Phosphatases and the Apurinic/Apyrimidinic Base Excision Repair Endonucleases Share a Common Mechanism for Catalysis

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.37055-37061

2000

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Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway

The FASEB journal, 2005-08, Vol.19 (10), p.1377-1379

2005

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Cleaved antitrypsin polymers at atomic resolution

Protein science, 2000-02, Vol.9 (2), p.417-420

2000

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The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G

Blood, 1999-03, Vol.93 (6), p.2089-2097

1999

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PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins

Nucleic acids research, 2011-01, Vol.39 (Database issue), p.D272

2011

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Osmolytes as Modulators of Conformational Changes in Serpins

Biological chemistry, 2001-11, Vol.382 (11), p.1593-1599

2001

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Identification and Characterization of a Misfolded Monomeric Serpin Formed at Physiological Temperature

Journal of molecular biology, 2010-10, Vol.403 (3), p.459-467

2010

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Human embryonic stem cell models of Huntington disease

Reproductive biomedicine online, 2009, Vol.19 (1), p.106-113

2009

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Studies on a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus: the role of tyrosine-53 in the reaction with human IgG

Biochemical journal, 2001-01, Vol.353 (Pt 2), p.395-401

2001

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Protein engineering of chimeric Serpins: an investigation into effects of the serpin scaffold and reactive centre loop length

Protein engineering, 1998-12, Vol.11 (12), p.1243-1247

1998

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Dissection of Protease-Activated Receptor-1-Dependent and -Independent Responses to Thrombin in Skeletal Myoblasts

Experimental cell research, 2002-03, Vol.274 (1), p.149-156

2002

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Protease-activated receptor-2 mediates proliferative responses in skeletal myoblasts

Journal of cell science, 2000-12, Vol.113 Pt 24 (24), p.4427-4433

2000

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Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state

Journal of molecular biology, 2001-11, Vol.313 (5), p.1161

2001

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Destabilization of a Non-pathological Variant of Ataxin-3 Results in Fibrillogenesis via a Partially Folded Intermediate: A Model for Misfolding in Polyglutamine Disease

Journal of molecular biology, 2004-01, Vol.335 (1), p.333-341

2004

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Complex between Peptostreptococcus magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Proteins

Structure (London), 2001-08, Vol.9 (8), p.679-687

2001

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Inhibitory Activity of a Heterochromatin-associated Serpin (MENT) against Papain-like Cysteine Proteinases Affects Chromatin Structure and Blocks Cell Proliferation

The Journal of biological chemistry, 2002-04, Vol.277 (15), p.13192-13201

2002

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REFOLD: An analytical database of protein refolding methods

Protein expression and purification, 2006-03, Vol.46 (1), p.166-171

2006

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PFD: a database for the investigation of protein folding kinetics and stability

Nucleic acids research, 2005-01, Vol.33 (Database issue), p.D279

2005

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Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins

Protein engineering, design and selection, 2009-08, Vol.22 (8), p.447-451

2009

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Intrinsic fluorescence changes and rapid kinetics of proteinase deformation during serpin inhibition

FEBS letters, 2001-04, Vol.494 (1), p.30-33

2001

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Elution of human IgG from affinity columns containing immobilised variants of protein A

Journal of immunological methods, 1995-06, Vol.182 (2), p.185-192

1995

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Equilibrium and pre-equilibrium fluorescence spectroscopic studies of the binding of a single-immunoglobulin-binding domain derived from protein G to the Fc fragment from human IgG1

Biochemical journal, 1995-08, Vol.310 ( Pt 1) (1), p.177-184

1995

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Thrombin, a Survival Factor for Cultured Myoblasts

The Journal of biological chemistry, 1999-04, Vol.274 (14), p.9169-9174

1999

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Mechanisms of Ataxin-3 Misfolding and Fibril Formation: Kinetic Analysis of a Disease-associated Polyglutamine Protein

Journal of molecular biology, 2007-04, Vol.368 (2), p.595-605

2007

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Towards the treatment of polyglutamine diseases: the modulatory role of protein context

The Inositol Polyphosphate 5-Phosphatases and the Apurinic/Apyrimidinic Base Excision Repair Endonucleases Share a Common Mechanism for Catalysis

Dopamine promotes α‐synuclein aggregation into SDS‐resistant soluble oligomers via a distinct folding pathway

Cleaved antitrypsin polymers at atomic resolution

The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G

PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins

Osmolytes as Modulators of Conformational Changes in Serpins

Identification and Characterization of a Misfolded Monomeric Serpin Formed at Physiological Temperature

Human embryonic stem cell models of Huntington disease

Studies on a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus: the role of tyrosine-53 in the reaction with human IgG

Protein engineering of chimeric Serpins: an investigation into effects of the serpin scaffold and reactive centre loop length

Dissection of Protease-Activated Receptor-1-Dependent and -Independent Responses to Thrombin in Skeletal Myoblasts

Protease-activated receptor-2 mediates proliferative responses in skeletal myoblasts

Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state

Destabilization of a Non-pathological Variant of Ataxin-3 Results in Fibrillogenesis via a Partially Folded Intermediate: A Model for Misfolding in Polyglutamine Disease

Complex between Peptostreptococcus magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Proteins

Inhibitory Activity of a Heterochromatin-associated Serpin (MENT) against Papain-like Cysteine Proteinases Affects Chromatin Structure and Blocks Cell Proliferation

REFOLD: An analytical database of protein refolding methods

PFD: a database for the investigation of protein folding kinetics and stability

Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins

Intrinsic fluorescence changes and rapid kinetics of proteinase deformation during serpin inhibition

Elution of human IgG from affinity columns containing immobilised variants of protein A

Equilibrium and pre-equilibrium fluorescence spectroscopic studies of the binding of a single-immunoglobulin-binding domain derived from protein G to the Fc fragment from human IgG1

Thrombin, a Survival Factor for Cultured Myoblasts

Mechanisms of Ataxin-3 Misfolding and Fibril Formation: Kinetic Analysis of a Disease-associated Polyglutamine Protein

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