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Dual-energy CT assessment of rapid monosodium urate depletion and bone erosion remodelling during pegloticase plus methotrexate co-therapy

Rheumatology (Oxford, England), 2022-11, Vol.61 (12), p.4898-4904

2022

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Improved joint and patient-reported health assessments with pegloticase plus methotrexate co-therapy in patients with uncontrolled gout: 12-month exploratory outcomes of the MIRROR open-label trial

Arthritis research & therapy, 2022-12, Vol.24 (1), p.281-8, Article 281

2022

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Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series

Journal of clinical rheumatology, 2022-01, Vol.28 (1), p.e129-e134

2022

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Pegloticase in Combination With Methotrexate in Patients With Uncontrolled Gout: A Multicenter, Open-label Study (MIRROR)

Journal of rheumatology, 2021-05, Vol.48 (5), p.767-774

2021

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The effect of immunomodulators on the efficacy and tolerability of pegloticase: a systematic review

Seminars in arthritis and rheumatism, 2021-04, Vol.51 (2), p.347-352

2021

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A Randomized, Placebo‐Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings

Arthritis & rheumatology (Hoboken, N.J.), 2023-02, Vol.75 (2), p.293-304

2023

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Controversies and practical management of patients with gout and chronic kidney disease

Kidney international, 2024-10, Vol.106 (4), p.573-582

2024

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Pegloticase hypersensitivity desensitisation: an outpatient, 3-bag, 12-step protocol

BMJ case reports, 2020-06, Vol.13 (6), p.e234721

Botson, John K

2020

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A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study

Arthritis research & therapy, 2022-08, Vol.24 (1), p.208-12, Article 208

2022

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A Randomized, Double‐Blind, Placebo‐Controlled Multicenter Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients With Uncontrolled Gout Receiving Pegloticase: 12‐Month Findings

ACR open rheumatology, 2023-08, Vol.5 (8), p.407-418

2023

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Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response

Current rheumatology reports, 2022, Vol.24 (1), p.12-19

2022

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Dual-Energy CT Bone Findings in Kidney Transplant Recipients with Uncontrolled Gout: FR-PO251

Journal of the American Society of Nephrology, 2024-10, Vol.35 (10S)

2024

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eGFR Changes in Uncontrolled Gout Patients Randomized to Receive Methotrexate or Placebo as Co-Therapy to Pegloticase: MIRROR RCT Findings: SA-PO898

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.851-851

2022

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Monosodium urate crystal depletion and bone erosion remodeling during pegloticase treatment in patients with uncontrolled gout: Exploratory dual-energy computed tomography findings from MIRROR RCT

Joint, bone, spine : revue du rhumatisme, 2024-07, Vol.91 (4), p.105715, Article 105715

2024

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Baseline Renal Characteristics and Trial Design for MIRROR RCT, Randomized Trial of Pegloticase with or Without Methotrexate for Uncontrolled Gout: PUB314

Journal of the American Society of Nephrology, 2021-10, Vol.32 (10S), p.852-852

2021

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Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

Arthritis research & therapy, 2020-05, Vol.22 (1), p.106-106, Article 106

2020

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TL1A-DR3 Interactions are Important in Both Adaptive and Innate Immunity in Inflammatory Arthritis

Clinical immunology (Orlando, Fla.), 2010, Vol.135, p.S88-S88

2010

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Changing the Standard of Care: The Case for Combining Pegloticase With Immunomodulatory Agents in Gout

Renal & urology news staff, 2022-04

Botson, Ccd John K

2022

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A Flexible Approach to Studying Post-Transcriptional Gene Regulation in Stably Transfected Mammalian Cells

Molecular biotechnology, 2011-07, Vol.48 (3), p.210-217

2011

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Epidemiological description of and response to a large yellow fever outbreak in Edo state Nigeria, September 2018 - January 2019

BMC public health, 2022-08, Vol.22 (1), p.1-1644, Article 1644

2022

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Dual-energy CT assessment of rapid monosodium urate depletion and bone erosion remodelling during pegloticase plus methotrexate co-therapy

Improved joint and patient-reported health assessments with pegloticase plus methotrexate co-therapy in patients with uncontrolled gout: 12-month exploratory outcomes of the MIRROR open-label trial

Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series

Pegloticase in Combination With Methotrexate in Patients With Uncontrolled Gout: A Multicenter, Open-label Study (MIRROR)

The effect of immunomodulators on the efficacy and tolerability of pegloticase: a systematic review

A Randomized, Placebo‐Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings

Controversies and practical management of patients with gout and chronic kidney disease

Pegloticase hypersensitivity desensitisation: an outpatient, 3-bag, 12-step protocol

A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study

A Randomized, Double‐Blind, Placebo‐Controlled Multicenter Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients With Uncontrolled Gout Receiving Pegloticase: 12‐Month Findings

Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response

Dual-Energy CT Bone Findings in Kidney Transplant Recipients with Uncontrolled Gout: FR-PO251

eGFR Changes in Uncontrolled Gout Patients Randomized to Receive Methotrexate or Placebo as Co-Therapy to Pegloticase: MIRROR RCT Findings: SA-PO898

Monosodium urate crystal depletion and bone erosion remodeling during pegloticase treatment in patients with uncontrolled gout: Exploratory dual-energy computed tomography findings from MIRROR RCT

Baseline Renal Characteristics and Trial Design for MIRROR RCT, Randomized Trial of Pegloticase with or Without Methotrexate for Uncontrolled Gout: PUB314

Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

TL1A-DR3 Interactions are Important in Both Adaptive and Innate Immunity in Inflammatory Arthritis

Changing the Standard of Care: The Case for Combining Pegloticase With Immunomodulatory Agents in Gout

A Flexible Approach to Studying Post-Transcriptional Gene Regulation in Stably Transfected Mammalian Cells

Epidemiological description of and response to a large yellow fever outbreak in Edo state Nigeria, September 2018 - January 2019

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