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Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades

Life sciences (1973), 2022-09, Vol.304, p.120695-120695, Article 120695

2022

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Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways

European journal of pharmacology, 2020-11, Vol.887, p.173461, Article 173461

2020

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Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

PLoS neglected tropical diseases, 2020-07, Vol.14 (7), p.e0008447

2020

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To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

International journal of molecular sciences, 2023-04, Vol.24 (7), p.6817

2023

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Chemical Profiling of Polyphenolics in Eucalyptus globulus and Evaluation of Its Hepato–Renal Protective Potential Against Cyclophosphamide Induced Toxicity in Mice

Antioxidants, 2019-09, Vol.8 (9), p.415

2019

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A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

Parasites & vectors, 2019-06, Vol.12 (1), p.304-304, Article 304

2019

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Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study

Journal of Traditional and Complementary Medicine, 2019-01, Vol.9 (1), p.45-53

2019

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Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.511-523

2020

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The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo

Experimental parasitology, 2020-01, Vol.208, p.107793-107793, Article 107793

2020

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Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection

Antimicrobial agents and chemotherapy, 2015-06, Vol.59 (6), p.3501-3508

2015

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Praziquantel resistance

Expert opinion on drug discovery, 2007-10, Vol.2 (S1), p.S35-S40

2007

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Resveratrol mitigates hepatic injury in rats by regulating oxidative stress, nuclear factor-kappa B, and apoptosis

Journal of advanced pharmaceutical technology and research, 2016-07, Vol.7 (3), p.99-104

2016

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Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

International journal for parasitology -- drugs and drug resistance, 2019-04, Vol.9, p.35-43

2019

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Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2010-09, Vol.118 (9), p.692-702

2010

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Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces

Pharmaceutical biology, 2016-12, Vol.54 (12), p.3172-3181

2016

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Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside Phosphonates Assessed by Schistosome Worm Killing In Vitro

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5284-5287

2009

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Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus

European journal of clinical pharmacology, 2016-05, Vol.72 (5), p.573-582

2016

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Response of Schistosoma mansoni Isolates Having Different Drug Sensitivity to Praziquantel Over Several Life Cycle Passages with and Without Therapeutic Pressure

The Journal of parasitology, 2008-04, Vol.94 (2), p.537-541

2008

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Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials

PLoS neglected tropical diseases, 2011-09, Vol.5 (9), p.e1285

2011

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Potential effect of the medicinal plants Calotropis procera. Ficus elastica and Zingiber officinale against Schistosoma mansoni in mice

Pharmaceutical biology, 2014-02, Vol.52 (2), p.144-150

2014

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Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent

BMC international health and human rights, 2012-07, Vol.12 (1), p.11-11, Article 11

2012

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Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates

International journal for parasitology, 2004-07, Vol.34 (8), p.979-987

2004

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Possible carcinogenic potential of dimethyl dimethoxy biphenyl dicarboxylate in experimental animals

Journal of advanced pharmaceutical technology and research, 2016-04, Vol.7 (2), p.54-58

2016

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Immunohistopathological and biochemical changes in Schistosoma mansoni -infected mice treated with artemether

The Journal of infection, 2007-11, Vol.55 (5), p.470-477

2007

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A model for southern mediterranean research institute self-assessment: A SWOT analysis-based approach to promote capacity building at Theodor Bilharz Research Institute in Cairo (Egypt)

Arab journal of gastroenterology, 2014-09, Vol.15 (3-4), p.92-97

2014

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Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades

Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

Chemical Profiling of Polyphenolics in Eucalyptus globulus and Evaluation of Its Hepato–Renal Protective Potential Against Cyclophosphamide Induced Toxicity in Mice

A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study

Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools

The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo

Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection

Praziquantel resistance

Resveratrol mitigates hepatic injury in rats by regulating oxidative stress, nuclear factor-kappa B, and apoptosis

Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment

Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces

Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside Phosphonates Assessed by Schistosome Worm Killing In Vitro

Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus

Response of Schistosoma mansoni Isolates Having Different Drug Sensitivity to Praziquantel Over Several Life Cycle Passages with and Without Therapeutic Pressure

Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials

Potential effect of the medicinal plants Calotropis procera. Ficus elastica and Zingiber officinale against Schistosoma mansoni in mice

Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent

Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates

Possible carcinogenic potential of dimethyl dimethoxy biphenyl dicarboxylate in experimental animals

Immunohistopathological and biochemical changes in Schistosoma mansoni -infected mice treated with artemether

A model for southern mediterranean research institute self-assessment: A SWOT analysis-based approach to promote capacity building at Theodor Bilharz Research Institute in Cairo (Egypt)

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