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Recent advances in understanding neurotrophin signaling

F1000 research, 2016, Vol.5, p.1885

Bothwell, Mark

2016

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Mechanisms and Medicines for Remyelination

Annual review of medicine, 2017-01, Vol.68 (1), p.431-443

Bothwell, Mark

2017

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Recent advances in understanding context-dependent mechanisms controlling neurotrophin signaling and function [version 1; peer review: 3 approved]

F1000 research, 2019, Vol.8, p.1658

Bothwell, Mark

2019

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Alternative Theory of AD Pathogenesis: Membrane Delimitation of the Histone Acetyltransferase Tip60/Kat5

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Activation of the p75 Neurotrophin Receptor through Conformational Rearrangement of Disulphide-Linked Receptor Dimers

Neuron (Cambridge, Mass.), 2009-04, Vol.62 (1), p.72-83

2009

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Conformational sampling of CMT-2D associated GlyRS mutations

Brain multiphysics, 2022, Vol.3, p.100054, Article 100054

2022

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Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells

PloS one, 2010-02, Vol.5 (2), p.e9135

2010

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TrkB downregulation is required for dendrite retraction in developing neurons of chicken nucleus magnocellularis

The Journal of neuroscience, 2012-10, Vol.32 (40), p.14000-14009

2012

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Editorial: Modeling neuromuscular diseases to determine molecular drivers of pathology and for drug discovery

Frontiers in cell and developmental biology, 2022-10, Vol.10, p.1017356-1017356

2022

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LIG Family Receptor Tyrosine Kinase-Associated Proteins Modulate Growth Factor Signals during Neural Development

Neuron (Cambridge, Mass.), 2009-09, Vol.63 (5), p.614-627

2009

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Human Induced Pluripotent Stem Cell-Derived TDP-43 Mutant Neurons Exhibit Consistent Functional Phenotypes Across Multiple Gene Edited Lines Despite Transcriptomic and Splicing Discrepancies

Frontiers in cell and developmental biology, 2021-09, Vol.9, p.728707-728707

2021

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Neurotrophin receptors: Old friends with new partners

Developmental neurobiology (Hoboken, N.J.), 2010-04, Vol.70 (5), p.332-338

2010

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Anterograde transport of neurotrophins and axodendritic transfer in the developing visual system

Nature (London), 1996-02, Vol.379 (6568), p.830-833

1996

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Eph Receptors and Ephrins in the Developing Chick Cerebellum: Relationship to Sagittal Patterning and Granule Cell Migration

The Journal of neuroscience, 2000-09, Vol.20 (17), p.6488-6500

2000

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Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure

The Journal of neuroscience, 2024-04, Vol.44 (16), p.e1787232024

2024

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Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

Neuron (Cambridge, Mass.), 1992-12, Vol.9 (6), p.1081-1088

1992

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Functional interactions of neurotrophins and neurotrophin receptors

Annual review of neuroscience, 1995-01, Vol.18 (1), p.223-253

BOTHWELL, M

1995

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Neurotrophin-3 Is Required for the Survival-Differentiation of Subsets of Developing Enteric Neurons

The Journal of neuroscience, 2001-08, Vol.21 (15), p.5620-5636

2001

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Astrocyte-derived extracellular vesicles enhance the survival and electrophysiological function of human cortical neurons in vitro

Biomaterials, 2021-04, Vol.271, p.120700-120700, Article 120700

2021

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FGF2 Alters Expression of the Pyrophosphate/Phosphate Regulating Proteins, PC-1, ANK and TNAP, in the Calvarial Osteoblastic Cell Line, MC3T3E1(C4)

Connective Tissue Research, 2005-01, Vol.46 (4-5), p.184-192

2005

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Evolution of the Neurotrophin Signaling System in Invertebrates

Brain, behavior and evolution, 2006-01, Vol.68 (3), p.124-132

Bothwell, Mark

2006

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Neurotrophins: To Cleave or Not to Cleave

Neuron, 2002-01, Vol.33 (1), p.9-12

2002

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p75$^{NTR}$: A Receptor After All

Science (American Association for the Advancement of Science), 1996-04, Vol.272 (5261), p.506-507

Bothwell, Mark

1996

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Intracellular Retention, Degradation, and Signaling of Glycosylation-deficient FGFR2 and Craniosynostosis Syndrome-associated FGFR2C278F

The Journal of biological chemistry, 2006-09, Vol.281 (37), p.27292-27305

2006

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LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments

The Journal of biological chemistry, 2015-04, Vol.290 (15), p.9511-9520

2015

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Recent advances in understanding neurotrophin signaling

Mechanisms and Medicines for Remyelination

Recent advances in understanding context-dependent mechanisms controlling neurotrophin signaling and function [version 1; peer review: 3 approved]

Alternative Theory of AD Pathogenesis: Membrane Delimitation of the Histone Acetyltransferase Tip60/Kat5

Activation of the p75 Neurotrophin Receptor through Conformational Rearrangement of Disulphide-Linked Receptor Dimers

Conformational sampling of CMT-2D associated GlyRS mutations

Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells

TrkB downregulation is required for dendrite retraction in developing neurons of chicken nucleus magnocellularis

Editorial: Modeling neuromuscular diseases to determine molecular drivers of pathology and for drug discovery

LIG Family Receptor Tyrosine Kinase-Associated Proteins Modulate Growth Factor Signals during Neural Development

Human Induced Pluripotent Stem Cell-Derived TDP-43 Mutant Neurons Exhibit Consistent Functional Phenotypes Across Multiple Gene Edited Lines Despite Transcriptomic and Splicing Discrepancies

Neurotrophin receptors: Old friends with new partners

Anterograde transport of neurotrophins and axodendritic transfer in the developing visual system

Eph Receptors and Ephrins in the Developing Chick Cerebellum: Relationship to Sagittal Patterning and Granule Cell Migration

Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure

Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

Functional interactions of neurotrophins and neurotrophin receptors

Neurotrophin-3 Is Required for the Survival-Differentiation of Subsets of Developing Enteric Neurons

Astrocyte-derived extracellular vesicles enhance the survival and electrophysiological function of human cortical neurons in vitro

FGF2 Alters Expression of the Pyrophosphate/Phosphate Regulating Proteins, PC-1, ANK and TNAP, in the Calvarial Osteoblastic Cell Line, MC3T3E1(C4)

Evolution of the Neurotrophin Signaling System in Invertebrates

Neurotrophins: To Cleave or Not to Cleave

p75$^{NTR}$: A Receptor After All

Intracellular Retention, Degradation, and Signaling of Glycosylation-deficient FGFR2 and Craniosynostosis Syndrome-associated FGFR2C278F

LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments

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