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Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

Regulatory toxicology and pharmacology, 2024-03, Vol.148, p.105585-105585, Article 105585

2024

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Acute systemic toxicity—prospects for tiered testing strategies

Toxicology in vitro, 2004-04, Vol.18 (2), p.227-230

Botham, P.A

2004

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Regulation of non-relevant metabolites of plant protection products in drinking and groundwater in the EU: Current status and way forward

Regulatory toxicology and pharmacology, 2015-10, Vol.73 (1), p.276-286

2015

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A prevalidation study on in vitro tests for acute skin irritation: results and evaluation by the Management Team

Toxicology in vitro, 2001-02, Vol.15 (1), p.57-93

2001

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P20-04 Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

Toxicology letters, 2024-09, Vol.399, p.S294-S294

2024

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Feasibility of the extended one-generation reproductive toxicity study (OECD 443)

Reproductive toxicology (Elmsford, N.Y.), 2012-11, Vol.34 (3), p.331-339

2012

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The EC/HO international validation study on alternatives to the draize eye irritation test

Toxicology in vitro, 1995-12, Vol.9 (6), p.871-929

1995

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The ECVAM International Validation Study on In Vitro Tests for Skin Corrosivity. 2. Results and Evaluation by the Management Team

Toxicology in vitro, 1998-08, Vol.12 (4), p.483-524

1998

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On the skin sensitisation potential of rosin and oxidised rosin

Regulatory toxicology and pharmacology, 2008-12, Vol.52 (3), p.257-263

2008

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Autonomous Reconfigurable Intelligent Surface based on Highly-Efficient Solar Cells

2023 17th European Conference on Antennas and Propagation (EuCAP), 2023, p.1-5

2023

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P19-05 Framework for classifying chemicals for repeat dose toxicity using NAMs

Toxicology letters, 2024-09, Vol.399, p.S255-S255

2024

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The validation of in vitro methods for skin irritation

Toxicology letters, 2004-04, Vol.149 (1), p.387-390

Botham, Philip A.

2004

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P21-21 Tiered testing and assessment to identify thyroid (hormone) disruptors

Toxicology letters, 2022-09, Vol.368, p.S265

2022

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Induction of respiratory hypersensitivity to diphenylmethane-4,4′-diisocyanate (MDI) in guinea pigs. Influence of route of exposure

Toxicology (Amsterdam), 1994-03, Vol.88 (1), p.15-30

1994

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Are serum thyroid hormone changes in rats a reliable indicator for human neurodevelopmental effects? -Evaluation of different cases

Toxicology letters, 2021-09, Vol.350, p.S140-S141

2021

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Rodent thyroid toxicity and potential child neurodevelopmental impairment

Toxicology letters, 2021-09, Vol.350, p.S137-S138

2021

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Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model

Journal of pharmacy & pharmaceutical sciences, 2003-01, Vol.6 (1), p.1-12

2003

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ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test

Alternatives to laboratory animals, 2007-12, Vol.35 (6), p.559-601

2007

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Absorption of angiotensin II antagonists in Ussing chambers, Caco-2, perfused jejunum loop and in vivo:: Importance of drug ionisation in the in vitro prediction of in vivo absorption

European journal of pharmaceutical sciences, 2000-05, Vol.10 (3), p.215-224

2000

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Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays

Food and chemical toxicology, 1993, Vol.31 (1), p.63-67

1993

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Skin sensitization—A critical review of predictive test methods in animals and man

Food and Chemical Toxicology, 1991, Vol.29 (4), p.275-286

1991

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The murine local lymph node assay: results of an inter-laboratory trial

Toxicology letters, 1991-02, Vol.55 (2), p.203-213

1991

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Allergy to laboratory animals: a follow up study of its incidence and of the influence of atopy and pre-existing sensitisation on its development

Occupational and environmental medicine (London, England), 1995-02, Vol.52 (2), p.129-133

1995

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A comparative study of the sensitivity of the 3-induction and 9-induction Buehler test procedures for assessing skin sensitisation potential

Food and chemical toxicology, 2005, Vol.43 (1), p.65-75

2005

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The induction of respiratory allergy in guinea-pigs following intradermal injection of trimellitic anhydride: a comparison with the response to 2,4-dinitrochlorobenzene

Toxicology letters, 1989-04, Vol.47 (1), p.25-39

1989

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Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

Acute systemic toxicity—prospects for tiered testing strategies

Regulation of non-relevant metabolites of plant protection products in drinking and groundwater in the EU: Current status and way forward

A prevalidation study on in vitro tests for acute skin irritation: results and evaluation by the Management Team

P20-04 Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

Feasibility of the extended one-generation reproductive toxicity study (OECD 443)

The EC/HO international validation study on alternatives to the draize eye irritation test

The ECVAM International Validation Study on In Vitro Tests for Skin Corrosivity. 2. Results and Evaluation by the Management Team

On the skin sensitisation potential of rosin and oxidised rosin

Autonomous Reconfigurable Intelligent Surface based on Highly-Efficient Solar Cells

P19-05 Framework for classifying chemicals for repeat dose toxicity using NAMs

The validation of in vitro methods for skin irritation

P21-21 Tiered testing and assessment to identify thyroid (hormone) disruptors

Induction of respiratory hypersensitivity to diphenylmethane-4,4′-diisocyanate (MDI) in guinea pigs. Influence of route of exposure

Are serum thyroid hormone changes in rats a reliable indicator for human neurodevelopmental effects? -Evaluation of different cases

Rodent thyroid toxicity and potential child neurodevelopmental impairment

Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model

ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test

Absorption of angiotensin II antagonists in Ussing chambers, Caco-2, perfused jejunum loop and in vivo:: Importance of drug ionisation in the in vitro prediction of in vivo absorption

Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays

Skin sensitization—A critical review of predictive test methods in animals and man

The murine local lymph node assay: results of an inter-laboratory trial

Allergy to laboratory animals: a follow up study of its incidence and of the influence of atopy and pre-existing sensitisation on its development

A comparative study of the sensitivity of the 3-induction and 9-induction Buehler test procedures for assessing skin sensitisation potential

The induction of respiratory allergy in guinea-pigs following intradermal injection of trimellitic anhydride: a comparison with the response to 2,4-dinitrochlorobenzene

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