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Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

The Journal of immunology (1950), 2021-01, Vol.206 (2), p.329-334

2021

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Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

Nature communications, 2021-04, Vol.12 (1), p.2295-2295, Article 2295

2021

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Route of Francisella tularensis infection informs spatiotemporal metabolic reprogramming and inflammation in mice

PloS one, 2023-10, Vol.18 (10), p.e0293450-e0293450

2023

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Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction

PLoS genetics, 2023-01, Vol.19 (1), p.e1010565-e1010565

2023

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The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

PloS one, 2024-02, Vol.19 (2), p.e0298095-e0298095

2024

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Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2

PloS one, 2022-05, Vol.17 (5), p.e0267720-e0267720

2022

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The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick

PLoS pathogens, 2022-03, Vol.18 (3), p.e1010385-e1010385

2022

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TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Cell reports (Cambridge), 2019-06, Vol.27 (11), p.3269-3283.e6

2019

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Lung environment determines unique phenotype of alveolar macrophages

American journal of physiology. Lung cellular and molecular physiology, 2009-06, Vol.296 (6), p.L936-L946

2009

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Francisella tularensis Induces Aberrant Activation of Pulmonary Dendritic Cells

Journal of Immunology, 2005-11, Vol.175 (10), p.6792-6801

2005

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Sex differences and individual variability in the captive Jamaican fruit bat (Artibeus jamaicensis) intestinal microbiome and metabolome

Scientific reports, 2024-02, Vol.14 (1), p.3381-3381, Article 3381

2024

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Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

Cell reports (Cambridge), 2022-07, Vol.40 (4), p.111144-111144, Article 111144

2022

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Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases

Molecular brain, 2021-10, Vol.14 (1), p.156-156, Article 156

2021

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Ebola and Marburg Viruses Replicate in Monocyte-Derived Dendritic Cells without Inducing the Production of Cytokines and Full Maturation

The Journal of infectious diseases, 2003-12, Vol.188 (11), p.1630-1638

2003

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Innate and Adaptive Immunity to Francisella

Annals of the New York Academy of Sciences, 2007-06, Vol.1105 (1), p.284-324

2007

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Unique Francisella Phosphatidylethanolamine Acts as a Potent Anti-Inflammatory Lipid

Journal of innate immunity, 2018-01, Vol.10 (4), p.291-305

2018

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Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

Infection and Immunity, 2009-01, Vol.77 (1), p.180-195

2009

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High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster

Viruses, 2021-12, Vol.13 (12), p.2506

2021

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Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques

JCI insight, 2023-02, Vol.8 (4)

2023

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Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

JCI insight, 2022-01, Vol.7 (2)

2022

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Generation of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemia

PloS one, 2012-03, Vol.7 (3), p.e33349-e33349

2012

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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

Nature (London), 2020-09, Vol.585 (7824), p.273-276

2020

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Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS

PLoS pathogens, 2012-01, Vol.8 (1), p.e1002494-e1002494

2012

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Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

Cell, 2021-10, Vol.184 (21), p.5338-5356.e21

2021

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Mastomys natalensis Has a Cellular Immune Response Profile Distinct from Laboratory Mice

Viruses, 2021-04, Vol.13 (5), p.729

2021

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Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

Route of Francisella tularensis infection informs spatiotemporal metabolic reprogramming and inflammation in mice

Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2

The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Lung environment determines unique phenotype of alveolar macrophages

Francisella tularensis Induces Aberrant Activation of Pulmonary Dendritic Cells

Sex differences and individual variability in the captive Jamaican fruit bat (Artibeus jamaicensis) intestinal microbiome and metabolome

Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases

Ebola and Marburg Viruses Replicate in Monocyte-Derived Dendritic Cells without Inducing the Production of Cytokines and Full Maturation

Innate and Adaptive Immunity to Francisella

Unique Francisella Phosphatidylethanolamine Acts as a Potent Anti-Inflammatory Lipid

Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster

Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques

Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

Generation of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemia

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS

Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

Mastomys natalensis Has a Cellular Immune Response Profile Distinct from Laboratory Mice

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