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Computer‐assisted engineering of hyperstable fibroblast growth factor 2

Biotechnology and bioengineering, 2018-04, Vol.115 (4), p.850-862

2018

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Colicin FY inhibits pathogenic Yersinia enterocolitica in mice

Scientific reports, 2018-08, Vol.8 (1), p.1-12, Article 12242

2018

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Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies

Human molecular genetics, 2018-03, Vol.27 (6), p.1093-1105

2018

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Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

Biomaterials, 2018-09, Vol.176, p.106-121

2018

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Freshwater Cyanotoxin Cylindrospermopsin Has Detrimental Stage-specific Effects on Hepatic Differentiation From Human Embryonic Stem Cells

Toxicological sciences, 2019-03, Vol.168 (1), p.241-251

2019

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Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4316-4325

2019

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Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome

Cellular signalling, 2018-01, Vol.42, p.144-154

2018

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An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome

Human molecular genetics, 2016-09, Vol.25 (18), p.3998-4011

2016

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Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Bone Research, 2022-04, Vol.10 (1), p.37, Article 37

2022

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Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling

Cells (Basel, Switzerland), 2021-06, Vol.10 (6), p.1445

2021

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Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

EMBO molecular medicine, 2020-11, Vol.12 (11), p.e11739-n/a

2020

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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

Oncotarget, 2017-12, Vol.8 (65), p.109319-109331

2017

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One reporter for in-cell activity profiling of majority of protein kinase oncogenes

eLife, 2017-02, Vol.6

2017

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Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR

Frontiers in cell and developmental biology, 2023-01, Vol.10, p.963389

2023

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Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia

EBioMedicine, 2020-12, Vol.62, p.103075-103075, Article 103075

2020

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Regulation of TAZ by DEPTOR controls mesenchymal progenitors lineage commitment in response to PTH1R signaling

Bone Reports, 2020-10, Vol.13, p.100602, Article 100602

2020

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Cilia kinases in skeletal development and homeostasis

Developmental dynamics, 2022-04, Vol.251 (4), p.577-608

2022

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Role of Primary Cilia in Odontogenesis

Journal of Dental Research, 2017-08, Vol.96 (9), p.965-974

2017

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Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling

Journal of bone and mineral research, 2021-11, Vol.36 (11), p.2258-2274

2021

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An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice

Science translational medicine, 2021-05, Vol.13 (592)

2021

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An Efficient Method for Generation of Knockout Human Embryonic Stem Cells Using CRISPR/Cas9 System

Stem cells and development, 2017-11, Vol.26 (21), p.1521-1527

2017

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Elucidation of protein interactions necessary for the maintenance of the BCR–ABL signaling complex

Cellular and molecular life sciences : CMLS, 2020-10, Vol.77 (19), p.3885-3903

2020

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ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

Bone (New York, N.Y.), 2017-12, Vol.105, p.57-66

2017

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Tyrosine Kinase Expressed in Hepatocellular Carcinoma, TEC, Controls Pluripotency and Early Cell Fate Decisions of Human Pluripotent Stem Cells via Regulation of Fibroblast Growth Factor‐2 Secretion

Stem cells (Dayton, Ohio), 2017-09, Vol.35 (9), p.2050-2059

2017

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Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport

Journal of proteome research, 2016-10, Vol.15 (10), p.3841-3855

2016

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Computer‐assisted engineering of hyperstable fibroblast growth factor 2

Colicin FY inhibits pathogenic Yersinia enterocolitica in mice

Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies

Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

Freshwater Cyanotoxin Cylindrospermopsin Has Detrimental Stage-specific Effects on Hepatic Differentiation From Human Embryonic Stem Cells

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome

Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

One reporter for in-cell activity profiling of majority of protein kinase oncogenes

Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR

Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia

Regulation of TAZ by DEPTOR controls mesenchymal progenitors lineage commitment in response to PTH1R signaling

Cilia kinases in skeletal development and homeostasis

Role of Primary Cilia in Odontogenesis

Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling

An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice

An Efficient Method for Generation of Knockout Human Embryonic Stem Cells Using CRISPR/Cas9 System

Elucidation of protein interactions necessary for the maintenance of the BCR–ABL signaling complex

ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

Tyrosine Kinase Expressed in Hepatocellular Carcinoma, TEC, Controls Pluripotency and Early Cell Fate Decisions of Human Pluripotent Stem Cells via Regulation of Fibroblast Growth Factor‐2 Secretion

Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport

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