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Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis

Pharmacological reports, 2020-12, Vol.72 (6), p.1553-1561

2020

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Novel betulin dicarboxylic acid ester derivatives as potent antiviral agents: Design, synthesis, biological evaluation, structure-activity relationship and in-silico study

European journal of medicinal chemistry, 2021-12, Vol.225, p.113738-113738, Article 113738

2021

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5,8-Quinolinedione Scaffold as a Promising Moiety of Bioactive Agents

Molecules (Basel, Switzerland), 2019-11, Vol.24 (22), p.4115

2019

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Design, Synthesis and Biological Evaluation of Quinoline-8-Sulfonamides as Inhibitors of the Tumor Cell-Specific M2 Isoform of Pyruvate Kinase: Preliminary Study

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2509

2023

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Lipophilicity, Pharmacokinetic Properties, and Molecular Docking Study on SARS-CoV-2 Target for Betulin Triazole Derivatives with Attached 1,4-Quinone

Pharmaceutics, 2021-05, Vol.13 (6), p.781

2021

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Novel Triazole Hybrids of Betulin: Synthesis and Biological Activity Profile

Molecules (Basel, Switzerland), 2017-11, Vol.22 (11), p.1876

2017

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The Influence of Betulin and Its Derivatives EB5 and ECH147 on the Antioxidant Status of Human Renal Proximal Tubule Epithelial Cells

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2524

2022

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Molecular Structure, In Vitro Anticancer Study and Molecular Docking of New Phosphate Derivatives of Betulin

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.737

2021

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The role of MITF and Mcl-1 proteins in the antiproliferative and proapoptotic effect of ciprofloxacin in amelanotic melanoma cells: In silico and in vitro study

Toxicology in vitro, 2020-08, Vol.66, p.104884-104884, Article 104884

2020

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Interaction between moxifloxacin and Mcl-1 and MITF proteins: the effect on growth inhibition and apoptosis in MDA-MB-231 human triple-negative breast cancer cells

Pharmacological reports, 2022-10, Vol.74 (5), p.1025-1040

2022

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Antiproliferative and Cytotoxic Properties of Propynoyl Betulin Derivatives against Human Ovarian Cancer Cells: In Vitro Studies

International journal of molecular sciences, 2023-11, Vol.24 (22), p.16487

2023

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The application of in silico experimental model in the assessment of ciprofloxacin and levofloxacin interaction with main SARS-CoV-2 targets: S-, E- and TMPRSS2 proteins, RNA-dependent RNA polymerase and papain-like protease (PLpro)—preliminary molecular docking analysis

Pharmacological reports, 2021-12, Vol.73 (6), p.1765-1780

2021

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Anticancer Activity of the Acetylenic Derivative of Betulin Phosphate Involves Induction of Necrotic-Like Death in Breast Cancer Cells In Vitro

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.615

2021

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Betulin-1,4-quinone hybrids: Synthesis, anticancer activity and molecular docking study with NQO1 enzyme

European journal of medicinal chemistry, 2019-09, Vol.177, p.302-315

2019

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Synthesis, structure and cytotoxic activity of new acetylenic derivatives of betulin

Molecules (Basel, Switzerland), 2013-04, Vol.18 (4), p.4526-4543

2013

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Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde

International journal of molecular sciences, 2019-03, Vol.20 (6), p.1372

2019

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Chromatographic and Computational Assessment of Lipophilicity of New Anticancer Acetylenequinoline Derivatives

Journal of chromatographic science, 2017-10, Vol.55 (9), p.934-939

2017

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New Phosphorus Analogs of Bevirimat: Synthesis, Evaluation of Anti-HIV-1 Activity and Molecular Docking Study

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5209

2019

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Acetylenic Synthetic Betulin Derivatives Inhibit Akt and Erk Kinases Activity, Trigger Apoptosis and Suppress Proliferation of Neuroblastoma and Rhabdomyosarcoma Cell Lines

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12299

2021

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Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives

Molecules (Basel, Switzerland), 2017-02, Vol.22 (2), p.300-300

2017

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Betulin Phosphonates; Synthesis, Structure, and Cytotoxic Activity

Molecules (Basel, Switzerland), 2016-08, Vol.21 (9), p.1123

2016

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Novel triazoles of 3-acetylbetulin and betulone as anticancer agents

Medicinal chemistry research, 2018, Vol.27 (9), p.2051-2061

2018

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The Influence of Betulin and Its Derivatives on Selected Colorectal Cancer Cell Lines' Viability and Their Antioxidant Systems

Cells (Basel, Switzerland), 2024-08, Vol.13 (16), p.1368

2024

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New 30-substituted derivatives of pentacyclic triterpenes: preparation, biological activity, and molecular docking study

Journal of molecular structure, 2021-02, Vol.1226, p.129394, Article 129394

2021

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Design, synthesis and biological activity of 1,4-quinone moiety attached to betulin derivatives as potent DT-diaphorase substrate

Bioorganic chemistry, 2021-01, Vol.106, p.104478-104478, Article 104478

2021

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Ciprofloxacin and moxifloxacin could interact with SARS-CoV-2 protease: preliminary in silico analysis

Novel betulin dicarboxylic acid ester derivatives as potent antiviral agents: Design, synthesis, biological evaluation, structure-activity relationship and in-silico study

5,8-Quinolinedione Scaffold as a Promising Moiety of Bioactive Agents

Design, Synthesis and Biological Evaluation of Quinoline-8-Sulfonamides as Inhibitors of the Tumor Cell-Specific M2 Isoform of Pyruvate Kinase: Preliminary Study

Lipophilicity, Pharmacokinetic Properties, and Molecular Docking Study on SARS-CoV-2 Target for Betulin Triazole Derivatives with Attached 1,4-Quinone

Novel Triazole Hybrids of Betulin: Synthesis and Biological Activity Profile

The Influence of Betulin and Its Derivatives EB5 and ECH147 on the Antioxidant Status of Human Renal Proximal Tubule Epithelial Cells

Molecular Structure, In Vitro Anticancer Study and Molecular Docking of New Phosphate Derivatives of Betulin

The role of MITF and Mcl-1 proteins in the antiproliferative and proapoptotic effect of ciprofloxacin in amelanotic melanoma cells: In silico and in vitro study

Interaction between moxifloxacin and Mcl-1 and MITF proteins: the effect on growth inhibition and apoptosis in MDA-MB-231 human triple-negative breast cancer cells

Antiproliferative and Cytotoxic Properties of Propynoyl Betulin Derivatives against Human Ovarian Cancer Cells: In Vitro Studies

The application of in silico experimental model in the assessment of ciprofloxacin and levofloxacin interaction with main SARS-CoV-2 targets: S-, E- and TMPRSS2 proteins, RNA-dependent RNA polymerase and papain-like protease (PLpro)—preliminary molecular docking analysis

Anticancer Activity of the Acetylenic Derivative of Betulin Phosphate Involves Induction of Necrotic-Like Death in Breast Cancer Cells In Vitro

Betulin-1,4-quinone hybrids: Synthesis, anticancer activity and molecular docking study with NQO1 enzyme

Synthesis, structure and cytotoxic activity of new acetylenic derivatives of betulin

Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde

Chromatographic and Computational Assessment of Lipophilicity of New Anticancer Acetylenequinoline Derivatives

New Phosphorus Analogs of Bevirimat: Synthesis, Evaluation of Anti-HIV-1 Activity and Molecular Docking Study

Acetylenic Synthetic Betulin Derivatives Inhibit Akt and Erk Kinases Activity, Trigger Apoptosis and Suppress Proliferation of Neuroblastoma and Rhabdomyosarcoma Cell Lines

Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives

Betulin Phosphonates; Synthesis, Structure, and Cytotoxic Activity

Novel triazoles of 3-acetylbetulin and betulone as anticancer agents

The Influence of Betulin and Its Derivatives on Selected Colorectal Cancer Cell Lines' Viability and Their Antioxidant Systems

New 30-substituted derivatives of pentacyclic triterpenes: preparation, biological activity, and molecular docking study

Design, synthesis and biological activity of 1,4-quinone moiety attached to betulin derivatives as potent DT-diaphorase substrate

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