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High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-peptide Inhibitor (UIC-94017) Active Against Multi-drug-resistant Clinical Strains

Journal of molecular biology, 2004-04, Vol.338 (2), p.341-352

2004

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Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1379-1387

2006

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Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir‐binding site

European journal of biochemistry, 2004-04, Vol.271 (8), p.1516-1524

2004

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Combining mutations in HIV-1 protease to understand mechanisms of resistance

Proteins, structure, function, and bioinformatics, 2002-07, Vol.48 (1), p.107-116

2002

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Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus In Vitro

Antimicrobial Agents and Chemotherapy, 2003-10, Vol.47 (10), p.3123-3129

2003

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The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden

Haematologica (Roma), 2011-12, Vol.96 (12), p.1822-1830

2011

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Narrow Substrate Specificity and Sensitivity toward Ligand-binding Site Mutations of Human T-cell Leukemia Virus Type 1 Protease

The Journal of biological chemistry, 2004-06, Vol.279 (26), p.27148-27157

2004

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Mechanism of Drug Resistance Revealed by the Crystal Structure of the Unliganded HIV-1 Protease with F53L Mutation

Journal of molecular biology, 2006-05, Vol.358 (5), p.1191-1199

2006

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HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions

Journal of molecular biology, 2007-09, Vol.372 (2), p.369-381

2007

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Bovine leukemia virus protease: comparison with human T-lymphotropic virus and human immunodeficiency virus proteases

Journal of general virology, 2007-07, Vol.88 (7), p.2052-2063

2007

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The Inhibitory Receptor FcγRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcγRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes

The American journal of pathology, 2003-11, Vol.163 (5), p.1839-1848

2003

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Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease

Journal of general virology, 2006-05, Vol.87 (5), p.1321-1330

2006

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Identification of Cytoplasmic Actin as an Abundant Glutaminyl Substrate for Tissue Transglutaminase in HL-60 and U937 Cells Undergoing Apoptosis

The Journal of biological chemistry, 1997-08, Vol.272 (33), p.20577-20583

1997

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Improved purification protocol for wild-type and mutant human foamy virus proteases

Protein expression and purification, 2006-04, Vol.46 (2), p.343-347

2006

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Development of a microtiter plate fluorescent assay for inhibition studies on the HTLV-1 and HIV-1 proteinases

Journal of virological methods, 2004-08, Vol.119 (2), p.87-93

2004

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A Novel Bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI), GRL-98065, Is Potent Against Mulutiple-PI-Resistant Human Immunodeficiency Virus in Vitro

Antimicrobial agents and chemotherapy, 2007-01, Vol.51 (6)

2007

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The complex role of Fcy receptors in the pathology of arthritis

Springer seminars in immunopathology, 2006-12, Vol.28 (4), p.339-350

2006

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Expression of the murine leukemia virus protease in fusion with maltose-binding protein in Escherichia coli

Protein expression and purification, 2004-05, Vol.35 (1), p.62-68

2004

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Human immunodeficiency virus type 1 capsid protein is a substrate of the retroviral proteinase while integrase is resistant toward proteolysis

Virology (New York, N.Y.), 2003-05, Vol.310 (1), p.16-23

2003

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Investigation of Processes Evolving during Thin Film Production by Laser Surface Modification

Materials science forum, 2005-01, Vol.473-474, p.303-308

2005

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Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication

Retrovirology, 2005-09, Vol.2 (1), p.58-58, Article 58

2005

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Expression and characterization of human foamy virus proteinase

FEBS letters, 1999-12, Vol.462 (3), p.397-401

1999

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Transforming Growth Factor-β Induced Protein, βIG-H3, is Present in Degraded Form and Altered Localization in Lattice Corneal Dystrophy Type I

Experimental eye research, 1998-06, Vol.66 (6), p.739-745

1998

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Coordinate expression of activating Fcγ receptors I and III and inhibiting Fcγ receptor type II in the determination of joint inflammation and cartilage destruction during immune complex–mediated arthritis

Arthritis and rheumatism, 2003-01, Vol.48 (1), p.255-265

2003

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Effect of sequence polymorphism and drug resistance on two HIV‐1 Gag processing sites

European journal of biochemistry, 2002-08, Vol.269 (16), p.4114-4120

2002

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High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-peptide Inhibitor (UIC-94017) Active Against Multi-drug-resistant Clinical Strains

Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M

Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir‐binding site

Combining mutations in HIV-1 protease to understand mechanisms of resistance

Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus In Vitro

The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden

Narrow Substrate Specificity and Sensitivity toward Ligand-binding Site Mutations of Human T-cell Leukemia Virus Type 1 Protease

Mechanism of Drug Resistance Revealed by the Crystal Structure of the Unliganded HIV-1 Protease with F53L Mutation

HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions

Bovine leukemia virus protease: comparison with human T-lymphotropic virus and human immunodeficiency virus proteases

The Inhibitory Receptor FcγRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcγRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes

Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease

Identification of Cytoplasmic Actin as an Abundant Glutaminyl Substrate for Tissue Transglutaminase in HL-60 and U937 Cells Undergoing Apoptosis

Improved purification protocol for wild-type and mutant human foamy virus proteases

Development of a microtiter plate fluorescent assay for inhibition studies on the HTLV-1 and HIV-1 proteinases

A Novel Bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI), GRL-98065, Is Potent Against Mulutiple-PI-Resistant Human Immunodeficiency Virus in Vitro

The complex role of Fcy receptors in the pathology of arthritis

Expression of the murine leukemia virus protease in fusion with maltose-binding protein in Escherichia coli

Human immunodeficiency virus type 1 capsid protein is a substrate of the retroviral proteinase while integrase is resistant toward proteolysis

Investigation of Processes Evolving during Thin Film Production by Laser Surface Modification

Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication

Expression and characterization of human foamy virus proteinase

Transforming Growth Factor-β Induced Protein, βIG-H3, is Present in Degraded Form and Altered Localization in Lattice Corneal Dystrophy Type I

Coordinate expression of activating Fcγ receptors I and III and inhibiting Fcγ receptor type II in the determination of joint inflammation and cartilage destruction during immune complex–mediated arthritis

Effect of sequence polymorphism and drug resistance on two HIV‐1 Gag processing sites

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