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Review article: therapeutic bile acids and the risks for hepatotoxicity

Alimentary pharmacology & therapeutics, 2018-06, Vol.47 (12), p.1623-1638

2018

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A genome-wide expression analysis identifies a network of EpCAM-induced cell cycle regulators

British journal of cancer, 2008-11, Vol.99 (10), p.1635-1643

2008

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The Liver Toxicity Knowledge Base: A Systems Approach to a Complex End Point

Clinical pharmacology and therapeutics, 2013-05, Vol.93 (5), p.409-412

2013

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A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts

Human molecular genetics, 2008-05, Vol.17 (10), p.1397-1405

2008

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3.3 Trovafloxacin: a case study of idiosyncratic or iatrogenic liver toxicity – molecular mechanisms and lessons for pharmacotoxicity

Human & experimental toxicology, 2009-02, Vol.28 (2-3), p.119-121

Borlak, J

2009

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The next innovation cycle in toxicogenomics: Environmental epigenetics

Mutation research, 2008-07, Vol.659 (1), p.158-165

2008

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Apolipoproteins D and E3 exert neurotrophic and synaptogenic effects in dorsal root ganglion cell cultures

Neuroscience, 2009-08, Vol.162 (2), p.282-291

2009

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Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation

Pharmacological reviews, 2004-06, Vol.56 (2), p.291-330

2004

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MiRNAs in drug induced steatosis and its link to human non-alcoholic fatty liver disease

Toxicology letters, 2015-10, Vol.238 (2), p.S24-S25

Borlak, J.

2015

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Pathology of flupirtine-induced liver injury: a histological and clinical study of six cases

Virchows Archiv : an international journal of pathology, 2011-06, Vol.458 (6), p.709-716

2011

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hepatocyte nuclear factor 6 (HNF6) and FOXA2 are key regulators in colorectal liver metastases

The FASEB journal, 2007-05, Vol.21 (7), p.1445-1462

2007

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GATA4 zinc finger mutations as a molecular rationale for septation defects of the human heart

Journal of medical genetics, 2005-05, Vol.42 (5), p.e32-e32

2005

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Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease

Journal of medical genetics, 2004-09, Vol.41 (9), p.684-690

2004

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Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression

Pharmacological reviews, 2002-03, Vol.54 (1), p.129-158

2002

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Impaired tissue clearance of verapamil in rat cardiac hypertrophy results in transcriptional repression of ion channels

Xenobiotica, 2010-04, Vol.40 (4), p.291-299

2010

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Cytochrome P450 mono‐oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat

British journal of pharmacology, 2000-08, Vol.130 (8), p.1745-1752

2000

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Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells

Xenobiotica, 2003-09, Vol.33 (9), p.927-943

2003

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Handbook of toxicogenomics: strategies and applications

Borlak, J rgen

2006

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Expression of basolateral and canalicular transporters in rat liver and cultures of primary hepatocytes

Xenobiotica, 2004-11, Vol.34 (11-12), p.935-947

2004

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Epigenetic silencing of the lung tumor suppressor cell adhesion molecule 1

Toxicology letters, 2016-09, Vol.258, p.S92-S92

2016

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Molecular Diagnosis of a Familial Nonhemolytic Hyperbilirubinemia (Gilbert's Syndrome) in Healthy Subjects

Hepatology (Baltimore, Md.), 2000-10, Vol.32 (4), p.792-795

2000

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Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactions

British journal of pharmacology, 2000-01, Vol.129 (2), p.331-342

2000

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Somatic mutations in cardiac malformations

Journal of medical genetics, 2006-08, Vol.43 (8), p.e45-e45

2006

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Hallmarks of ion channel gene expression in end‐stage heart failure

The FASEB journal, 2003-09, Vol.17 (12), p.1592-1608

2003

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Correlation versus causation? Pharmacovigilance of the analgesic flupirtine exemplifies the need for refined spontaneous ADR reporting

PloS one, 2011-10, Vol.6 (10), p.e25221

2011

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Review article: therapeutic bile acids and the risks for hepatotoxicity

A genome-wide expression analysis identifies a network of EpCAM-induced cell cycle regulators

The Liver Toxicity Knowledge Base: A Systems Approach to a Complex End Point

A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts

3.3 Trovafloxacin: a case study of idiosyncratic or iatrogenic liver toxicity – molecular mechanisms and lessons for pharmacotoxicity

The next innovation cycle in toxicogenomics: Environmental epigenetics

Apolipoproteins D and E3 exert neurotrophic and synaptogenic effects in dorsal root ganglion cell cultures

Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation

MiRNAs in drug induced steatosis and its link to human non-alcoholic fatty liver disease

Pathology of flupirtine-induced liver injury: a histological and clinical study of six cases

hepatocyte nuclear factor 6 (HNF6) and FOXA2 are key regulators in colorectal liver metastases

GATA4 zinc finger mutations as a molecular rationale for septation defects of the human heart

Somatic NKX2-5 mutations as a novel mechanism of disease in complex congenital heart disease

Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression

Impaired tissue clearance of verapamil in rat cardiac hypertrophy results in transcriptional repression of ion channels

Cytochrome P450 mono‐oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat

Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells

Handbook of toxicogenomics: strategies and applications

Expression of basolateral and canalicular transporters in rat liver and cultures of primary hepatocytes

Epigenetic silencing of the lung tumor suppressor cell adhesion molecule 1

Molecular Diagnosis of a Familial Nonhemolytic Hyperbilirubinemia (Gilbert's Syndrome) in Healthy Subjects

Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactions

Somatic mutations in cardiac malformations

Hallmarks of ion channel gene expression in end‐stage heart failure

Correlation versus causation? Pharmacovigilance of the analgesic flupirtine exemplifies the need for refined spontaneous ADR reporting

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