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Matrix metalloprotease inhibitors: design from structure

Biochemical Society transactions, 2004-02, Vol.32 (Pt 1), p.17

Borkakoti, N

2004

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Matrix metalloproteases: variations on a theme

Progress in biophysics and molecular biology, 1998-01, Vol.70 (1), p.73-94

Borkakoti, N.

1998

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Tess: A geometric hashing algorithm for deriving 3D coordinate templates for searching structural databases. Application to enzyme active sites

Protein science, 1997-11, Vol.6 (11), p.2308-2323

1997

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Analysis of Catalytic Residues in Enzyme Active Sites

Journal of molecular biology, 2002-11, Vol.324 (1), p.105-121

2002

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Structural studies of matrix metalloproteinases

Journal of molecular medicine (Berlin, Germany), 2000-01, Vol.78 (5), p.261-268

BORKAKOTI, N

2000

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Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor

Nature structural & molecular biology, 1994-02, Vol.1 (2), p.106-110

1994

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From structure to function: approaches and limitations

Nature structural & molecular biology, 2000-11, Vol.7 Suppl (11s), p.991-994

2000

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Catalysing New Reactions during Evolution: Economy of Residues and Mechanism

Journal of molecular biology, 2003-08, Vol.331 (4), p.829-860

2003

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Design and synthesis of the cartilage protective agent (CPA, Ro32-3555)

Bioorganic & medicinal chemistry letters, 1997-09, Vol.7 (17), p.2299-2302

1997

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Protein interactions in the herpes simplex virus type 1 VP16-induced complex: VP16 peptide inhibition and mutational analysis of host cell factor requirements

Journal of Virology, 1997-05, Vol.71 (5), p.3886-3894

1997

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Collagenase Inhibitors: Their Design and Potential Therapeutic Use

Journal of enzyme inhibition, 1987, Vol.2 (1), p.1-22

1987

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Overcoming crystallisation obstacles in the pharmaceutical industry

Acta crystallographica. Section A, Foundations of crystallography, 2004-08, Vol.60 (a1), p.s56-s56

Borkakoti, N.

2004

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Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1691-1694

2003

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Ribonuclease-A: least-squares refinement of the structure at 1.45 Å resolution

Acta Crystallographica Section B, 1982-08, Vol.38 (8), p.2210-2217

1982

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Comparison of two independently refined models of ribonuclease-A

Acta crystallographica. Section B, Structural science, 1986-08, Vol.42 (4), p.379-387

1986

Volltextzugriff (PDF)

Mutagenesis studies of interleukin-8. Identification of a second epitope involved in receptor binding

The Journal of biological chemistry, 1996-04, Vol.271 (16), p.9579-9586

1996

Volltextzugriff (PDF)

Restrained structure-factor least-squares refinement of protein structures using a vector processing computer

Acta crystallographica. Section A, Foundations of crystallography, 1985-09, Vol.41 (5), p.426-433

1985

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Solvent-induced distortions and the curvature of α -helices

Nature (London), 1983-01, Vol.306 (5940), p.281-283

1983

Volltextzugriff (PDF)

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

Biochemical journal, 1997-04, Vol.323 ( Pt 2) (2), p.483-488

1997

Volltextzugriff (PDF)

Structure-based design of peptidomimetic antagonists of p56(lck) SH2 domain

Bioorganic & medicinal chemistry letters, 2002-05, Vol.12 (10), p.1365-1369

2002

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Zinc Endoproteases: A Structural Superfamily

Structure-Based Ligand Design, 1998, p.73-88

1998

Volltextzugriff (PDF)

Enzyme specificity: base recognition and hydrolysis of RNA by ribonuclease A

FEBS letters, 1983-10, Vol.162 (2), p.367-373

Borkakoti, Nivedita

1983

Volltextzugriff (PDF)

The active Site of Ribonuclease A from the Crystallographic Studies of Ribonuclease‐A‐Inhibitor Complexes

European journal of biochemistry, 1983-01, Vol.132 (1), p.89-94

BORKAKOTI, Nivedita

1983

Volltextzugriff (PDF)

The crystal structure and conformational variations of 5'-methylthioadenosine

Acta Crystallographica Section B, 1978-03, Vol.34 (3), p.867-874

1978

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Identification and characterisation of an inhibitor of interleukin-8: a receptor based approach

Bioorganic & medicinal chemistry letters, 1996-08, Vol.6 (15), p.1869-1874

1996

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Matrix metalloprotease inhibitors: design from structure

Matrix metalloproteases: variations on a theme

Tess: A geometric hashing algorithm for deriving 3D coordinate templates for searching structural databases. Application to enzyme active sites

Analysis of Catalytic Residues in Enzyme Active Sites

Structural studies of matrix metalloproteinases

Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor

From structure to function: approaches and limitations

Catalysing New Reactions during Evolution: Economy of Residues and Mechanism

Design and synthesis of the cartilage protective agent (CPA, Ro32-3555)

Protein interactions in the herpes simplex virus type 1 VP16-induced complex: VP16 peptide inhibition and mutational analysis of host cell factor requirements

Collagenase Inhibitors: Their Design and Potential Therapeutic Use

Overcoming crystallisation obstacles in the pharmaceutical industry

Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening

Ribonuclease-A: least-squares refinement of the structure at 1.45 Å resolution

Comparison of two independently refined models of ribonuclease-A

Mutagenesis studies of interleukin-8. Identification of a second epitope involved in receptor binding

Restrained structure-factor least-squares refinement of protein structures using a vector processing computer

Solvent-induced distortions and the curvature of α -helices

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

Structure-based design of peptidomimetic antagonists of p56(lck) SH2 domain

Zinc Endoproteases: A Structural Superfamily

Enzyme specificity: base recognition and hydrolysis of RNA by ribonuclease A

The active Site of Ribonuclease A from the Crystallographic Studies of Ribonuclease‐A‐Inhibitor Complexes

The crystal structure and conformational variations of 5'-methylthioadenosine

Identification and characterisation of an inhibitor of interleukin-8: a receptor based approach

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