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The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

eLife, 2017-11, Vol.6

2017

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Aiding and abetting cancer: mRNA export and the nuclear pore

Trends in cell biology, 2013-07, Vol.23 (7), p.328-335

2013

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A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

RNA (Cambridge), 2017-06, Vol.23 (6), p.927-937

2017

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The oncogene eIF4E: using biochemical insights to target cancer

Journal of interferon & cytokine research, 2013-05, Vol.33 (5), p.227-238

2013

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The RING finger domain: a recent example of a sequence—structure family

Current opinion in structural biology, 1996-06, Vol.6 (3), p.395-401

1996

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RING fingers and B-boxes: zinc-binding protein-protein interaction domains

Biochemistry and cell biology, 1998-05, Vol.76 (2-3), p.351-358

Borden, Katherine LB

1998

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eIF4E is a central node of an RNA regulon that governs cellular proliferation

The Journal of cell biology, 2006-11, Vol.175 (3), p.415-426

2006

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UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML

Oncogene, 2003-03, Vol.22 (11), p.1620-1628

2003

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The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

Cell reports (Cambridge), 2012-08, Vol.2 (2), p.207-215

2012

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Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

Cancer research (Chicago, Ill.), 2004-12, Vol.64 (23), p.8639-8642

2004

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Biochemical and Structural Insights into the Eukaryotic Translation Initiation Factor eIF4E

Current protein & peptide science, 2019-01, Vol.20 (6), p.525-535

2019

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mRNA export and cancer

Wiley interdisciplinary reviews. RNA, 2012-01, Vol.3 (1), p.13-25

2012

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The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH : a RING may link hematopoiesis and growth control

Oncogene, 1999-11, Vol.18 (50), p.7091-7100

1999

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The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity

The EMBO journal, 2007-01, Vol.26 (1), p.90-101

2007

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PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

Genes & development, 2008-08, Vol.22 (15), p.2085-2092

2008

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Activation Loop Phosphorylation of ERK3/ERK4 by Group I p21-activated Kinases (PAKs) Defines a Novel PAK-ERK3/4-MAPK-activated Protein Kinase 5 Signaling Pathway

The Journal of biological chemistry, 2011-02, Vol.286 (8), p.6470-6478

2011

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eIF4E RNA regulon promotes the Akt signaling pathway

The Journal of cell biology, 2008-04, Vol.181 (1), p.51-63

2008

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Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands

The EMBO journal, 2006-11, Vol.25 (21), p.5138-5149

2006

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Control of p53 multimerization by Ubc13 is JNK-regulated

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (31), p.12676-12681

2009

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Regulation of p53 Localization and Activity by Ubc13

Molecular and Cellular Biology, 2006-12, Vol.26 (23), p.8901-8913

2006

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Targeting the oncogene eIF4E in cancer: From the bench to clinical trials

Clinical and investigative medicine, 2011-12, Vol.34 (6), p.E315-E315

Borden, Katherine Lb

2011

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Inducible drug modification: A new form of resistance

Cell cycle (Georgetown, Tex.), 2014, Vol.13 (16), p.2485-2486

2014

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Importin 8 mediates m^sup 7^G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5263

2016

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The Eukaryotic Translation Initiation Factor 4E (eIF4E) Has Oncogenic Functions and May Represent a New Therapeutic Target In Diffuse Large B Cell Lymphoma (DLBCL)

Blood, 2013-11, Vol.122 (21), p.3785-3785

2013

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Eukaryotic Translation Initiation Factor 4E Activity Is Modulated by HOXA9 at Multiple Levels

Molecular and Cellular Biology, 2005-02, Vol.25 (3), p.1100-1112

2005

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The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

Aiding and abetting cancer: mRNA export and the nuclear pore

A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

The oncogene eIF4E: using biochemical insights to target cancer

The RING finger domain: a recent example of a sequence—structure family

RING fingers and B-boxes: zinc-binding protein-protein interaction domains

eIF4E is a central node of an RNA regulon that governs cellular proliferation

UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML

The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

Biochemical and Structural Insights into the Eukaryotic Translation Initiation Factor eIF4E

mRNA export and cancer

The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH : a RING may link hematopoiesis and growth control

The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

Activation Loop Phosphorylation of ERK3/ERK4 by Group I p21-activated Kinases (PAKs) Defines a Novel PAK-ERK3/4-MAPK-activated Protein Kinase 5 Signaling Pathway

eIF4E RNA regulon promotes the Akt signaling pathway

Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands

Control of p53 multimerization by Ubc13 is JNK-regulated

Regulation of p53 Localization and Activity by Ubc13

Targeting the oncogene eIF4E in cancer: From the bench to clinical trials

Inducible drug modification: A new form of resistance

Importin 8 mediates m^sup 7^G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

The Eukaryotic Translation Initiation Factor 4E (eIF4E) Has Oncogenic Functions and May Represent a New Therapeutic Target In Diffuse Large B Cell Lymphoma (DLBCL)

Eukaryotic Translation Initiation Factor 4E Activity Is Modulated by HOXA9 at Multiple Levels

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