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Characterization of CYP3A5 Selective Inhibitors for Reaction Phenotyping of Drug Candidates

The AAPS journal, 2024-02, Vol.26 (2), p.26-26, Article 26

2024

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Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes

The AAPS journal, 2024-03, Vol.26 (3), p.36, Article 36

2024

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Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT 1A partial agonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (2), p.865-868

2011

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Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT₁A partial agonists

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (2), p.865-868

2011

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Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT sub(1A) partial agonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (2), p.865-868

2011

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Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α2C adrenergic receptor antagonist

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5689-5693

2008

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Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin- 2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective alpha sub(2C) adrenergic receptor antagonist

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5689-5693

2008

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Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α 2C adrenergic receptor antagonist

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (20), p.5689-5693

2008

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Pharmacological Assessment of γ-Secretase Activity from Rodent and Human Brain

Neuroscience and medicine, 2012-06, Vol.3 (2), p.149-161

2012

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Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective alpha2C adrenergic receptor antagonist

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5689-5693

2008

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Lymphocyte development of adherence and motility in extracellular matrix during IL-2 stimulation

The Journal of immunology (1950), 1992-07, Vol.149 (2), p.681-688

1992

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Benralizumab for adolescent patients with severe, eosinophilic asthma: Safety and efficacy after 3 years of treatment

Journal of allergy and clinical immunology, 2021-07, Vol.148 (1), p.266-271.e2

2021

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Paclitaxel: biosynthesis, production and future prospects

New biotechnology, 2014-05, Vol.31 (3), p.242-245

2014

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Switchable Single-Walled Carbon Nanotube–Polymer Composites for CO2 Sensing

ACS applied materials & interfaces, 2018-10, Vol.10 (39), p.33373-33379

2018

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Understanding passive film degradation and its effect on hydrogen embrittlement of super duplex stainless steel – Synchrotron X-ray and electrochemical measurements combined with CalPhaD and ab-initio computational studies

Applied surface science, 2023-08, Vol.628, p.157364, Article 157364

2023

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A phase II study of talimogene laherparepvec for patients with inoperable locoregional recurrence of breast cancer

Scientific reports, 2021-11, Vol.11 (1), p.22242-8, Article 22242

2021

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Confounder Adjustment Using the Disease Risk Score: A Proposal for Weighting Methods

American journal of epidemiology, 2024-02, Vol.193 (2), p.377-388

2024

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The causation of hydrogen embrittlement of duplex stainless steel: Phase instability of the austenite phase and ductile-to-brittle transition of the ferrite phase – Synergy between experiments and modelling

Corrosion science, 2023-06, Vol.217, p.111140, Article 111140

2023

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Flexible Chemiresistive Cyclohexanone Sensors Based on Single-Walled Carbon Nanotube–Polymer Composites

ACS sensors, 2021-08, Vol.6 (8), p.3056-3062

2021

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Discovery and clinical introduction of first-in-class imipridone ONC201

Oncotarget, 2016-11, Vol.7 (45), p.74380-74392

2016

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Formation, Clearance, Deposition, Pathogenicity, and Identification of Biopharmaceutical-related Immune Complexes: Review and Case Studies

Toxicologic pathology, 2014-06, Vol.42 (4), p.725-764

2014

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White-Matter Abnormalities in Adolescents with Long-Term Inhalant and Cannabis Use: A Diffusion Magnetic Resonance Imaging Study

Journal of psychiatry & neuroscience, 2010-11, Vol.35 (6), p.409-412

2010

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Switchable Single-Walled Carbon Nanotube-Polymer Composites for CO 2 Sensing

ACS applied materials & interfaces, 2018-10, Vol.10 (39), p.33373-33379

2018

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A Randomized Phase II Study of Sequential Eribulin Versus Paclitaxel Followed by FAC/FEC as Neoadjuvant Therapy in Patients with Operable HER2‐Negative Breast Cancer

The oncologist (Dayton, Ohio), 2021-02, Vol.26 (2), p.e230-e240

2021

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Prevalence and associated risk factors of violence against conflict-affected female adolescents: a multi-country, cross-sectional study

Journal of global health, 2017-06, Vol.7 (1), p.010416-010416

2017

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Characterization of CYP3A5 Selective Inhibitors for Reaction Phenotyping of Drug Candidates

Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes

Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT 1A partial agonists

Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT₁A partial agonists

Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT sub(1A) partial agonists

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α2C adrenergic receptor antagonist

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin- 2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective alpha sub(2C) adrenergic receptor antagonist

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective α 2C adrenergic receptor antagonist

Pharmacological Assessment of γ-Secretase Activity from Rodent and Human Brain

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective alpha2C adrenergic receptor antagonist

Lymphocyte development of adherence and motility in extracellular matrix during IL-2 stimulation

Benralizumab for adolescent patients with severe, eosinophilic asthma: Safety and efficacy after 3 years of treatment

Paclitaxel: biosynthesis, production and future prospects

Switchable Single-Walled Carbon Nanotube–Polymer Composites for CO2 Sensing

Understanding passive film degradation and its effect on hydrogen embrittlement of super duplex stainless steel – Synchrotron X-ray and electrochemical measurements combined with CalPhaD and ab-initio computational studies

A phase II study of talimogene laherparepvec for patients with inoperable locoregional recurrence of breast cancer

Confounder Adjustment Using the Disease Risk Score: A Proposal for Weighting Methods

The causation of hydrogen embrittlement of duplex stainless steel: Phase instability of the austenite phase and ductile-to-brittle transition of the ferrite phase – Synergy between experiments and modelling

Flexible Chemiresistive Cyclohexanone Sensors Based on Single-Walled Carbon Nanotube–Polymer Composites

Discovery and clinical introduction of first-in-class imipridone ONC201

Formation, Clearance, Deposition, Pathogenicity, and Identification of Biopharmaceutical-related Immune Complexes: Review and Case Studies

White-Matter Abnormalities in Adolescents with Long-Term Inhalant and Cannabis Use: A Diffusion Magnetic Resonance Imaging Study

Switchable Single-Walled Carbon Nanotube-Polymer Composites for CO 2 Sensing

A Randomized Phase II Study of Sequential Eribulin Versus Paclitaxel Followed by FAC/FEC as Neoadjuvant Therapy in Patients with Operable HER2‐Negative Breast Cancer

Prevalence and associated risk factors of violence against conflict-affected female adolescents: a multi-country, cross-sectional study

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