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Minireview: Challenges and Opportunities in Development of PPAR Agonists

Molecular endocrinology (Baltimore, Md.), 2014-11, Vol.28 (11), p.1756-1768

2014

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Examining the safety of PPAR agonists - current trends and future prospects

Expert opinion on drug safety, 2013-01, Vol.12 (1), p.65-79

2013

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Case studies or how to deal with ‘difficult’ results

Toxicology letters, 2013-08, Vol.221, p.S34-S34

Bopst, Martin

2013

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Unexpected neurotoxicity in chronic toxicity studies with a HBV viral expression inhibitor

Regulatory toxicology and pharmacology, 2023-06, Vol.141, p.105407-105407, Article 105407

2023

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Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite

Regulatory toxicology and pharmacology, 2017-06, Vol.86, p.107-116

2017

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An innovative investigative approach to characterize the effects observed in a combined fertility study in male and female rats

Regulatory toxicology and pharmacology, 2018-06, Vol.95, p.339-347

2018

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The combined inactivation of tumor necrosis factor and interleukin‐6 prevents induction of the major acute phase proteins by endotoxin

European journal of immunology, 1998-12, Vol.28 (12), p.4130-4137

1998

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Potential confounding effects of benzyl alcohol as a formulation excipient support the elimination of the abnormal toxicity test from pharmacopoeias

Regulatory toxicology and pharmacology, 2015-11, Vol.73 (2), p.509-514

2015

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Historical Data Analyses and Scientific Knowledge Suggest Complete Removal of the Abnormal Toxicity Test as a Quality Control Test

Journal of pharmaceutical sciences, 2014-11, Vol.103 (11), p.3349-3355

2014

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Modern science for better quality control of medicinal products “Towards global harmonization of 3Rs in biologicals”: The report of an EPAA workshop

Biologicals, 2017-07, Vol.48, p.55-65

2017

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Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis

The Journal of experimental medicine, 1997-06, Vol.185 (12), p.2177-2182

1997

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Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-? gene knockout mice

Hepatology (Baltimore, Md.), 1998-04, Vol.27 (4), p.1021-1029

1998

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Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin‐α gene knockout mice

Hepatology (Baltimore, Md.), 1998-04, Vol.27 (4), p.1021-1029

1998

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Differential effects of TNF and LTα in the host defense against M. bovis BCG

European journal of immunology, 2001-06, Vol.31 (6), p.1935-1943

2001

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The role of proinflammatory cytokines in inflammation and host defense : experimental models for the acute inflammatory response, tuberculosis, and NSAID-induced gastrointestinal toxicity in gene-deficient mice

Bopst, Martin

1997

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Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-α gene knockout in mice

European journal of gastroenterology & hepatology, 1998-07, Vol.10 (7), p.626

1998

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Minireview: Challenges and Opportunities in Development of PPAR Agonists

Examining the safety of PPAR agonists - current trends and future prospects

Case studies or how to deal with ‘difficult’ results

Unexpected neurotoxicity in chronic toxicity studies with a HBV viral expression inhibitor

Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite

An innovative investigative approach to characterize the effects observed in a combined fertility study in male and female rats

The combined inactivation of tumor necrosis factor and interleukin‐6 prevents induction of the major acute phase proteins by endotoxin

Potential confounding effects of benzyl alcohol as a formulation excipient support the elimination of the abnormal toxicity test from pharmacopoeias

Historical Data Analyses and Scientific Knowledge Suggest Complete Removal of the Abnormal Toxicity Test as a Quality Control Test

Modern science for better quality control of medicinal products “Towards global harmonization of 3Rs in biologicals”: The report of an EPAA workshop

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis

Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-? gene knockout mice

Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin‐α gene knockout mice

Differential effects of TNF and LTα in the host defense against M. bovis BCG

The role of proinflammatory cytokines in inflammation and host defense : experimental models for the acute inflammatory response, tuberculosis, and NSAID-induced gastrointestinal toxicity in gene-deficient mice

Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-α gene knockout in mice

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