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Use of category approaches, read-across and (Q)SAR: General considerations

Regulatory toxicology and pharmacology, 2013-10, Vol.67 (1), p.1-12

2013

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Assessment of the three-test genetic toxicology battery for groundwater metabolites

Mutagenesis, 2024-03, Vol.39 (2), p.146-155

2024

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Toward Good Read-Across Practice (GRAP) guidance

ALTEX, alternatives to animal experimentation, 2016, Vol.33 (2), p.149-166

2016

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Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites

Environmental and molecular mutagenesis, 2017-06, Vol.58 (5), p.325-344

2017

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Read-across approaches--misconceptions, promises and challenges ahead

ALTEX, alternatives to animal experimentation, 2014, Vol.31 (4), p.387-396

2014

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Use of read-across to simplify the toxicological assessment of a complex mixture of lysimeter leachate metabolites on the basis of chemical similarity and ADME behavior

Regulatory toxicology and pharmacology, 2017-02, Vol.83, p.109-116

2017

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Review of the in vitro and in vivo genotoxicity of dichlorvos

Regulatory toxicology and pharmacology, 2007-12, Vol.49 (3), p.316-326

2007

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Re-evaluation of the big blue® mouse assay of propiconazole suggests lack of mutagenicity

Environmental and molecular mutagenesis, 2012-01, Vol.53 (1), p.1-9

2012

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Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3- 14C]-butadiene

Chemico-biological interactions, 2004-03, Vol.147 (2), p.213-232

2004

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Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3- [formula omitted]]-butadiene

Chemico-biological interactions, 2004-03, Vol.147 (2), p.195-211

2004

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DNA adducts in rats and mice following exposure to [4- [formula omitted]]-1,2-epoxy-3-butene and to [2,3- [formula omitted]]-1,3-butadiene

Chemico-biological interactions, 2004-06, Vol.148 (1), p.69-92

2004

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Metabolic distribution of radioactivity in Sprague–Dawley rats and B6C3F1 mice exposed to 1,3-[2,3- 14C]–butadiene by whole body exposure

Chemico-biological interactions, 2003-05, Vol.145 (2), p.175-189

2003

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Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA

Nucleic acids research, 1990-10, Vol.18 (19), p.5617-5623

1990

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Influence of pH on the conformation and stability of mismatch base-pairs in DNA

Journal of molecular biology, 1990-04, Vol.212 (3), p.437-440

1990

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Crystal structure and stability of a DNA duplex containing A( anti) · G( syn) base-pairs

Journal of molecular biology, 1989-05, Vol.207 (2), p.455-457

1989

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Studies on the dermal and systemic bioavailability of polycyclic aromatic compounds in high viscosity oil products

Archives of toxicology, 1999-06, Vol.73 (3), p.129-140

1999

Volltextzugriff (PDF)

t4 report: Toward Good Read-Across Practice (GRAP) Guidance

ALTEX, alternatives to animal experimentation, 2016-01, Vol.33 (2), p.149-166

2016

Volltextzugriff (PDF)

Development of a carcinogenic potency index for dermal exposure to viscous oil products

Archives of toxicology, 1999-04, Vol.73 (3), p.180-188

1999

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Correlation of 32 P-postlabelling-detection of DNA adducts in mouse skin in vivo with the polycyclic aromatic compound content and mutagenicity in Salmonella typhimurium of a range of oil products

Archives of toxicology, 1998-08, Vol.72 (8), p.505-513

1998

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The conformational variability of an adenosine inosine base-pair in a synthetic DNA dodecamer

Nucleic acids research, 1992-09, Vol.20 (18), p.4753-4759

1992

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Effects of solvent on DNA adduct formation in skin and lung of CD1 mice exposed cutaneously to benzo(a)pyrene

Archives of toxicology, 1999-08, Vol.73 (6), p.316-322

1999

Volltextzugriff (PDF)

Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts1Dedicated to Erika Randerath, deceased August 23rd, 1997.1

Chemico-biological interactions, 1998-03, Vol.110 (1-2), p.85-102

1998

Volltextzugriff (PDF)

Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts

Chemico-biological interactions, 1998-03, Vol.110 (1), p.85-102

1998

Volltextzugriff (PDF)

Structural studies in dna

Booth, Ewan D

1991

Volltextzugriff (PDF)

The Incorporation of 2,6-Diaminopurine Into Oligodeoxyribonucleotides by the Phosphoramidite Method

Nucleosides & nucleotides, 1989-01, Vol.8 (5-6), p.1051-1051

1989

Volltextzugriff (PDF)

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Biochemistry & Molecular Biology
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Biological And Medical Sciences
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Pharmacology & Pharmacy
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Humans
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Mice, Inbred Strains
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Butadienes - Administration & Dosage
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Use of category approaches, read-across and (Q)SAR: General considerations

Assessment of the three-test genetic toxicology battery for groundwater metabolites

Toward Good Read-Across Practice (GRAP) guidance

Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites

Read-across approaches--misconceptions, promises and challenges ahead

Use of read-across to simplify the toxicological assessment of a complex mixture of lysimeter leachate metabolites on the basis of chemical similarity and ADME behavior

Review of the in vitro and in vivo genotoxicity of dichlorvos

Re-evaluation of the big blue® mouse assay of propiconazole suggests lack of mutagenicity

Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3- 14C]-butadiene

Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3- [formula omitted]]-butadiene

DNA adducts in rats and mice following exposure to [4- [formula omitted]]-1,2-epoxy-3-butene and to [2,3- [formula omitted]]-1,3-butadiene

Metabolic distribution of radioactivity in Sprague–Dawley rats and B6C3F1 mice exposed to 1,3-[2,3- 14C]–butadiene by whole body exposure

Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA

Influence of pH on the conformation and stability of mismatch base-pairs in DNA

Crystal structure and stability of a DNA duplex containing A( anti) · G( syn) base-pairs

Studies on the dermal and systemic bioavailability of polycyclic aromatic compounds in high viscosity oil products

t4 report: Toward Good Read-Across Practice (GRAP) Guidance

Development of a carcinogenic potency index for dermal exposure to viscous oil products

Correlation of 32 P-postlabelling-detection of DNA adducts in mouse skin in vivo with the polycyclic aromatic compound content and mutagenicity in Salmonella typhimurium of a range of oil products

The conformational variability of an adenosine inosine base-pair in a synthetic DNA dodecamer

Effects of solvent on DNA adduct formation in skin and lung of CD1 mice exposed cutaneously to benzo(a)pyrene

Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts1Dedicated to Erika Randerath, deceased August 23rd, 1997.1

Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts

Structural studies in dna

The Incorporation of 2,6-Diaminopurine Into Oligodeoxyribonucleotides by the Phosphoramidite Method

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