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Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production

Journal of medicinal chemistry, 2004-05, Vol.47 (11), p.2724-2727

2004

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The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2399-2403

2005

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Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1250-1253

2007

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Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5633-5638

2006

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Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines

Journal of medicinal chemistry, 2001-03, Vol.44 (7), p.1060-1071

2001

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Development of New Hydroxamate Matrix Metalloproteinase Inhibitors Derived from Functionalized 4-Aminoprolines

Journal of medicinal chemistry, 2000-12, Vol.43 (26), p.4948-4963

2000

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The development of monocyclic pyrazolone based cytokine synthesis inhibitors

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2285-2289

2005

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Development of N-2,4-pyrimidine-N-phenyl-N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3510-3513

2006

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Pyrazolones as therapeutics for kinase-mediated inflammatory disorders

Expert opinion on therapeutic patents, 2005-11, Vol.15 (11), p.1617-1623

2005

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The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-α production

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4360-4365

2006

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Development of N-2,4-pyrimidine-N-phenyl-N′-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 2

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3514-3518

2006

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The development of novel inhibitors of tumor necrosis factor-α (TNF-α) production based on substituted [5,5]-bicyclic pyrazolones

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4267-4272

2004

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The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

Bioorganic & medicinal chemistry letters, 2004-10, Vol.14 (19), p.4945-4948

2004

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The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (15), p.1975-1979

2001

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Induction of Bradyrhizobium japonicum common nod genes by isoflavones isolated from Glycine max

Proceedings of the National Academy of Sciences - PNAS, 1987-11, Vol.84 (21), p.7428-7432

1987

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Synthesis and protein body deposition of maize 15‐kd zein in transgenic tobacco seeds

The EMBO journal, 1987-11, Vol.6 (11), p.3213-3221

1987

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The development of novel inhibitors of tumor necrosis factor-alpha production based on substituted [5,5]-bicyclic pyrozolones

Bioorganic & medicinal chemistry, 2010-11, Vol.14 ((16) ; 2004)

2010

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Molecular cloning and characterization of the insecticidal crystal protein gene of Bacillus thuringiensis var. tenebrionis

Proceedings of the National Academy of Sciences - PNAS, 1987-10, Vol.84 (20), p.7036-7040

1987

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Convergent synthesis of 2,3-bisarylpyrazolones through cyclization of bisacylated pyrazolidines and hydrazines

Tetrahedron letters, 2006-05, Vol.47 (19), p.3195-3198

2006

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Corrigendum to “Development of N-2,4-pyrimidine- N-phenyl- N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1” [Bioorg. Med. Chem. Lett. 16 (2006) 3510–3513]

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (17), p.4700-4700

2006

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Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production

Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)

Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3

Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines

Development of New Hydroxamate Matrix Metalloproteinase Inhibitors Derived from Functionalized 4-Aminoprolines

The development of monocyclic pyrazolone based cytokine synthesis inhibitors

Development of N-2,4-pyrimidine-N-phenyl-N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1

Pyrazolones as therapeutics for kinase-mediated inflammatory disorders

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-α production

Development of N-2,4-pyrimidine-N-phenyl-N′-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 2

The development of novel inhibitors of tumor necrosis factor-α (TNF-α) production based on substituted [5,5]-bicyclic pyrazolones

The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold

Induction of Bradyrhizobium japonicum common nod genes by isoflavones isolated from Glycine max

Synthesis and protein body deposition of maize 15‐kd zein in transgenic tobacco seeds

The development of novel inhibitors of tumor necrosis factor-alpha production based on substituted [5,5]-bicyclic pyrozolones

Molecular cloning and characterization of the insecticidal crystal protein gene of Bacillus thuringiensis var. tenebrionis

Convergent synthesis of 2,3-bisarylpyrazolones through cyclization of bisacylated pyrazolidines and hydrazines

Corrigendum to “Development of N-2,4-pyrimidine- N-phenyl- N′-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-α) synthesis. Part 1” [Bioorg. Med. Chem. Lett. 16 (2006) 3510–3513]

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