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Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution

Critical reviews in toxicology, 2018-10, Vol.48 (9), p.796-814

2018

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Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement

Archives of toxicology, 2017-02, Vol.91 (2), p.1001-1006

2017

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New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop

Regulatory toxicology and pharmacology, 2020-07, Vol.114, p.104668, Article 104668

2020

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Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

Toxicology research (Cambridge), 2018-05, Vol.7 (3), p.347-357

2018

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Mode of Action in Relevance of Rodent Liver Tumors to Human Cancer Risk

Toxicological sciences, 2006-01, Vol.89 (1), p.51-56

2006

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Expression of P450 enzymes in rat whole skin and cultured epidermal keratinocytes

Biochemical and biophysical research communications, 2002-09, Vol.297 (1), p.65-70

2002

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Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension

British journal of clinical pharmacology, 2005-07, Vol.60 (1), p.107-112

2005

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Evidence for genotoxicity of pesticides in pesticide applicators: a review

Mutagenesis, 2006-03, Vol.21 (2), p.93-103

2006

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Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism

Drug metabolism and disposition, 2003-06, Vol.31 (6), p.755-761

2003

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Risk characterisation of chemicals in food and diet

Food and chemical toxicology, 2003-09, Vol.41 (9), p.1211-1271

2003

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Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview

Critical reviews in toxicology, 2011-03, Vol.41 (3), p.175-186

2011

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Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis

The European respiratory journal, 1997-04, Vol.10 (4), p.795-803

1997

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CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A71C allele

Pharmacogenetics and genomics, 2005-09, Vol.15 (9), p.625-631

2005

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Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism

British journal of clinical pharmacology, 2003-01, Vol.55 (1), p.68-76

2003

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The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man

Biochemical pharmacology, 1989-09, Vol.38 (17), p.2795-2799

1989

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Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans

Carcinogenesis (New York), 2004-09, Vol.25 (9), p.1659-1669

2004

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Determination of a human hepatic microsomal scaling factor for predicting in vivo drug clearance

Pharmaceutical research, 2006-03, Vol.23 (3), p.533-539

2006

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A Tiered Approach to Systemic Toxicity Testing for Agricultural Chemical Safety Assessment

Critical reviews in toxicology, 2006, Vol.36 (1), p.37-68

2006

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Diazinon Is Activated by CYP2C19 in Human Liver

Toxicology and applied pharmacology, 2001-11, Vol.177 (1), p.68-76

2001

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Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices

Drug metabolism and disposition, 2003-03, Vol.31 (3), p.282-288

2003

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Interlaboratory comparison of the assessment of P450 activities in human hepatic microsomal samples

Xenobiotica, 1998-05, Vol.28 (5), p.493-506

1998

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Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man

British journal of clinical pharmacology, 1990-06, Vol.29 (6), p.651-663

1990

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Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man

Carcinogenesis (New York), 2001-09, Vol.22 (9), p.1413-1420

2001

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Development of a Comprehensive Panel of Antibodies against the Major Xenobiotic Metabolising Forms of Cytochrome P450 in Humans

Biochemical pharmacology, 1998-08, Vol.56 (3), p.377-387

1998

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Agricultural Chemical Safety Assessment: A Multisector Approach to the Modernization of Human Safety Requirements

Critical reviews in toxicology, 2006, Vol.36 (1), p.1-7

2006

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Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution

Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement

New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

Mode of Action in Relevance of Rodent Liver Tumors to Human Cancer Risk

Expression of P450 enzymes in rat whole skin and cultured epidermal keratinocytes

Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension

Evidence for genotoxicity of pesticides in pesticide applicators: a review

Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism

Risk characterisation of chemicals in food and diet

Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview

Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis

CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A71C allele

Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism

The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man

Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans

Determination of a human hepatic microsomal scaling factor for predicting in vivo drug clearance

A Tiered Approach to Systemic Toxicity Testing for Agricultural Chemical Safety Assessment

Diazinon Is Activated by CYP2C19 in Human Liver

Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices

Interlaboratory comparison of the assessment of P450 activities in human hepatic microsomal samples

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man

Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man

Development of a Comprehensive Panel of Antibodies against the Major Xenobiotic Metabolising Forms of Cytochrome P450 in Humans

Agricultural Chemical Safety Assessment: A Multisector Approach to the Modernization of Human Safety Requirements

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