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Current challenges in a paradigm shift for cancer risk assessment

Toxicology letters, 2021-09, Vol.350, p.S40-S40

Boobis, A.R.

2021

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A framework for a fit-for-purpose evaluation of non-animal methods

Toxicology letters, 2018-10, Vol.295, p.S17-S17

Boobis, A.R.

2018

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Evidence for genotoxicity of pesticides in pesticide applicators: a review

Mutagenesis, 2006-03, Vol.21 (2), p.93-103

2006

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Improving the integration of exposure assessment in human health risk assessments

Toxicology letters, 2016-10, Vol.259, p.S13-S13

Boobis, A.R.

2016

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Test and Risk Assessment Strategies for combined exposure to multiple chemicals

Food and chemical toxicology, 2020-10, Vol.144, p.111607-111607, Article 111607

2020

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The significance of sample mass in the analysis of steroid estrogens in sewage sludges and the derivation of partition coefficients in wastewaters

Journal of Chromatography A, 2009-06, Vol.1216 (24), p.4923-4926

2009

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Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution

Critical reviews in toxicology, 2018-10, Vol.48 (9), p.796-814

2018

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CEC07-01 Introduction to TTC – concept, databases, excluded substances and sources of uncertainty

Toxicology letters, 2022-09, Vol.368, p.S8

2022

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Risk characterisation of chemicals in food and diet

Food and chemical toxicology, 2003-09, Vol.41 (9), p.1211-1271

2003

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Differential expression and regulation of members of the cytochrome P450IA gene subfamily in human tissues

Carcinogenesis (New York), 1990-07, Vol.11 (7), p.1183-1188

1990

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Searching for novel biomarkers of centrally and peripehrally-acting neurotoxicants, using surface-enhanced laser desorption/ionisation-time-of-flight mass spectrometry (SELDI-TOF MS)

Food and chemical toxicology, 2007-11, Vol.45 (11), p.2126-2137

2007

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Organ distinctive mutagenicity in MutaTMMouse after short-term exposure to PhIP

Mutagenesis, 1996-09, Vol.11 (5), p.505-509

1996

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Comparative physicochemical and pharmacokinetic profiles of inhaled beclomethasone dipropionate and budesonide

Respiratory medicine, 1998-07, Vol.92, p.2-6

Boobis, A.R.

1998

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Co-localization of P450 enzymes in the rat substantia nigra with tyrosine hydroxylase

Neuroscience, 1998-09, Vol.86 (2), p.511-519

1998

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Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phnylimidazo(4,5-b)pyridine (PhIP) by human liver microsomes

Carcinogenesis (New York), 1994-06, Vol.15 (6), p.1285-1288

1994

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Cell cycle and gene expression changes in response to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in human TK6 Cells

Toxicology (Amsterdam), 2000-07, Vol.148 (1), p.60-61

2000

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Cell cycle and gene expression changes in response to [formula omitted] (PhIP) in human TK6 Cells

Toxicology (Amsterdam), 2000, Vol.148 (1), p.60-61

2000

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Assay of caffeine metabolism in vitro by human liver microsomes using radio-high-performance liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis [J. PHARM. BIOMED. ANAL.]. Vol. 8, no. 8-12. 1990, 1990, Vol.8 (8), p.783-787

1990

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Routes of activation of 4,4′-methylenebis-(2-chloroaniline) and 4,4′-methylenedianiline to bacterial mutagens

Food and Chemical Toxicology [FOOD CHEM. TOXICOL.]. Vol. 24, no. 6-7. 1986, 1986-06, Vol.24 (6), p.755-756

1986

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Combined assay for phenacetin and paracetamol in plasma using capillary column gas chromatography—negative-ion mass spectrometry

Journal of chromatography, 1991-08, Vol.568 (2), p.341-350

1991

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Mode of inhibition of quinidine and quinine on debrisoquine 4-hydroxylase. Extrapolation from rats to humans

Rinshō yakuri, 1989, Vol.20 (1), p.125-126

1989

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Genetic analysis of PHIP intestinal mutations in MutaTMMouse

Mutagenesis, 1998-11, Vol.13 (6), p.601-605

1998

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Production of specific antibodies against CYP3A1 and CYP3A2 in the rat

Toxicology letters, 1995-08, Vol.78, p.27-27

1995

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Identification of a pro-inhibitory region on the surface of human CYP1A2

Toxicology letters, 1995-08, Vol.78, p.16-16

1995

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The Practical Applicability of Hepatocyte Cultures in Routine Testing: The Report and Recommendations of ECVAM Workshop 1

Alternatives to laboratory animals, 1994-07, Vol.22 (4), p.231-241

1994

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Current challenges in a paradigm shift for cancer risk assessment

A framework for a fit-for-purpose evaluation of non-animal methods

Evidence for genotoxicity of pesticides in pesticide applicators: a review

Improving the integration of exposure assessment in human health risk assessments

Test and Risk Assessment Strategies for combined exposure to multiple chemicals

The significance of sample mass in the analysis of steroid estrogens in sewage sludges and the derivation of partition coefficients in wastewaters

Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution

CEC07-01 Introduction to TTC – concept, databases, excluded substances and sources of uncertainty

Risk characterisation of chemicals in food and diet

Differential expression and regulation of members of the cytochrome P450IA gene subfamily in human tissues

Searching for novel biomarkers of centrally and peripehrally-acting neurotoxicants, using surface-enhanced laser desorption/ionisation-time-of-flight mass spectrometry (SELDI-TOF MS)

Organ distinctive mutagenicity in MutaTMMouse after short-term exposure to PhIP

Comparative physicochemical and pharmacokinetic profiles of inhaled beclomethasone dipropionate and budesonide

Co-localization of P450 enzymes in the rat substantia nigra with tyrosine hydroxylase

Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phnylimidazo(4,5-b)pyridine (PhIP) by human liver microsomes

Cell cycle and gene expression changes in response to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in human TK6 Cells

Cell cycle and gene expression changes in response to [formula omitted] (PhIP) in human TK6 Cells

Assay of caffeine metabolism in vitro by human liver microsomes using radio-high-performance liquid chromatography

Routes of activation of 4,4′-methylenebis-(2-chloroaniline) and 4,4′-methylenedianiline to bacterial mutagens

Combined assay for phenacetin and paracetamol in plasma using capillary column gas chromatography—negative-ion mass spectrometry

Mode of inhibition of quinidine and quinine on debrisoquine 4-hydroxylase. Extrapolation from rats to humans

Genetic analysis of PHIP intestinal mutations in MutaTMMouse

Production of specific antibodies against CYP3A1 and CYP3A2 in the rat

Identification of a pro-inhibitory region on the surface of human CYP1A2

The Practical Applicability of Hepatocyte Cultures in Routine Testing: The Report and Recommendations of ECVAM Workshop 1

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