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Drosophila as an In Vivo Model for Human Neurodegenerative Disease

Genetics (Austin), 2015-10, Vol.201 (2), p.377-402

2015

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MicroRNAs and neurodegeneration: role and impact

Trends in cell biology, 2013-01, Vol.23 (1), p.30-36

2013

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Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization

Molecular cell, 2018-09, Vol.71 (5), p.703-717.e9

2018

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A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity

Current biology, 2012-04, Vol.22 (7), p.590-595

2012

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Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease

Nature neuroscience, 2018-04, Vol.21 (4), p.497-505

2018

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Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

PLoS genetics, 2007-10, Vol.3 (10), p.1950-1964

2007

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MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging

Nature communications, 2018-10, Vol.9 (1), p.4188-13, Article 4188

2018

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Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation

Biochemistry (Easton), 2018-12, Vol.57 (51), p.6923-6926

2018

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RNA toxicity is a component of ataxin-3 degeneration in Drosophila

Nature, 2008-06, Vol.453 (7198), p.1107-1111

2008

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DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (21), p.9747-9752

2010

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A perspective on Drosophila genetics and its insight into human neurodegenerative disease

Frontiers in molecular biosciences, 2022-11, Vol.9, p.1060796-1060796

Bonini, Nancy M

2022

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Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model

PLoS genetics, 2013-09, Vol.9 (9), p.e1003781

2013

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The Exoribonuclease Nibbler Controls 3′ End Processing of MicroRNAs in Drosophila

Current biology, 2011-11, Vol.21 (22), p.1888-1893

2011

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Drosophila as a model for human neurodegenerative disease

Annual review of genetics, 2005-01, Vol.39 (1), p.153-171

2005

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Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD

Nature neuroscience, 2019-06, Vol.22 (6), p.863-874

2019

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Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy

PLoS genetics, 2011-03, Vol.7 (3), p.e1001340

2011

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Mettl3-dependent m6A modification attenuates the brain stress response in Drosophila

Nature communications, 2022-09, Vol.13 (1), p.5387-5387, Article 5387

2022

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GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function

eLife, 2015-12, Vol.4, p.e08881-e08881

2015

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Epigenetic Regulation in Neurodegenerative Diseases

Trends in neurosciences (Regular ed.), 2018-09, Vol.41 (9), p.587-598

2018

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dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain

Scientific reports, 2023-12, Vol.13 (1), p.22999-22999, Article 22999

2023

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Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila

Genes & development, 2014-01, Vol.28 (1), p.44-57

2014

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MicroRNA Pathways Modulate Polyglutamine-Induced Neurodegeneration

Molecular cell, 2006-10, Vol.24 (1), p.157-163

2006

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Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

Nature communications, 2018-10, Vol.9 (1), p.4406-13, Article 4406

2018

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Chaperoning Brain Degeneration

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (suppl_4), p.16407-16411

Bonini, Nancy M.

2002

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Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila

PLoS biology, 2008-02, Vol.6 (2), p.e29-e29

2008

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Drosophila as an In Vivo Model for Human Neurodegenerative Disease

MicroRNAs and neurodegeneration: role and impact

Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization

A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity

Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease

Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging

Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation

RNA toxicity is a component of ataxin-3 degeneration in Drosophila

DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

A perspective on Drosophila genetics and its insight into human neurodegenerative disease

Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model

The Exoribonuclease Nibbler Controls 3′ End Processing of MicroRNAs in Drosophila

Drosophila as a model for human neurodegenerative disease

Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD

Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy

Mettl3-dependent m6A modification attenuates the brain stress response in Drosophila

GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function

Epigenetic Regulation in Neurodegenerative Diseases

dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain

Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila

MicroRNA Pathways Modulate Polyglutamine-Induced Neurodegeneration

Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

Chaperoning Brain Degeneration

Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila

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