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Direct control of CAR T cells through small molecule-regulated antibodies

Nature communications, 2021-01, Vol.12 (1), p.710-10, Article 710

2021

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Control of Chemokine-Guided Cell Migration by Ligand Sequestration

Cell, 2008-02, Vol.132 (3), p.463-473

2008

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Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation

Scientific reports, 2024-09, Vol.14 (1), p.21331-14, Article 21331

2024

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1047 Protein design and inducible expression allow context-dependent, localized IL-12 activity to enhance solid tumor T cell therapies

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1154-A1154

2023

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Killing the messenger: The role of CXCR7 in regulating primordial germ cell migration

Cell adhesion & migration, 2008-04, Vol.2 (2), p.69-70

2008

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GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma

The New England journal of medicine, 2023-06, Vol.388 (24), p.2303-2304

2023

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Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma

Molecular therapy, 2019-06, Vol.27 (6), p.1126-1138

2019

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Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells

Cancer cell, 2012-03, Vol.21 (3), p.402-417

2012

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Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

Cancer cell, 2014-11, Vol.26 (5), p.638-652

2014

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RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

Cell, 2007-12, Vol.131 (7), p.1273-1286

2007

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A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo

Nature cell biology, 2010-01, Vol.12 (1), p.47-53

2010

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Abstract LB-150: Local maturation and inhibition of antitumor CD8 T-cell responses in a model of immunoevasive breast cancer

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.LB-150-LB-150

2014

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A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies

Scientific reports, 2018-06, Vol.8 (1), p.8972-8, Article 8972

2018

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Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

Cancer cell, 2014-12, Vol.26 (6), p.938-938

2014

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Abstract 3239: SMIC CAR T cells: CAR T with temporally-controlled, programmable cytokine signaling outputs

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3239-3239

2020

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Adaptive Immune Regulation of Mammary Postnatal Organogenesis

Developmental cell, 2015-09, Vol.34 (5), p.493-504

2015

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Abstract LB-182: Differential modulation of the PD-1 pathway impacts the anti-tumor activity of CAR T cells

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.LB-182-LB-182

2017

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Tumor-infiltrating lymphocytes are dynamically desensitized to antigen but are maintained by homeostatic cytokine

JCI insight, 2016-12, Vol.1 (20), p.e89289-e89289

2016

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ALLO-715, an Allogeneic BCMA CAR T Therapy Possessing an Off-Switch for the Treatment of Multiple Myeloma

Blood, 2018-11, Vol.132 (Supplement 1), p.591-591

2018

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Allogeneic Anti-Bcma CAR-T Cells Show Tumour Specific Killing Against Primary Multiple Myeloma Cells from Different Genomic Sub-Groups

Blood, 2019-11, Vol.134 (Supplement_1), p.1834-1834

2019

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Design and Validation of Inducible TurboCARs with Tunable Induction and Combinatorial Cytokine Signaling

Cancer immunology research, 2022-09, Vol.10 (9), p.1069-1083

2022

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Allogeneic Anti-BCMA CAR T Cells Are Superior to Multiple Myeloma-derived CAR T Cells in Preclinical Studies and May Be Combined with Gamma Secretase Inhibitors

Cancer research communications, 2022-03, Vol.2 (3), p.158-171

2022

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Abstract 4067: Development of tumor-restricted IL-12 with antigen-dependent expression and localized IL-12 activity

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.4067-4067

2024

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Preclinical Evaluation of Allogeneic Anti-Bcma Chimeric Antigen Receptor T Cells with Safety Switch Domains and Lymphodepletion Resistance for the Treatment of Multiple Myeloma

Blood, 2016-12, Vol.128 (22), p.381-381

2016

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Cxcl12 evolution--subfunctionalization of a ligand through altered interaction with the chemokine receptor

Development (Cambridge), 2011-07, Vol.138 (14), p.2909-2914

2011

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Direct control of CAR T cells through small molecule-regulated antibodies

Control of Chemokine-Guided Cell Migration by Ligand Sequestration

Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation

1047 Protein design and inducible expression allow context-dependent, localized IL-12 activity to enhance solid tumor T cell therapies

Killing the messenger: The role of CXCR7 in regulating primordial germ cell migration

GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma

Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma

Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo

Abstract LB-150: Local maturation and inhibition of antitumor CD8 T-cell responses in a model of immunoevasive breast cancer

A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

Abstract 3239: SMIC CAR T cells: CAR T with temporally-controlled, programmable cytokine signaling outputs

Adaptive Immune Regulation of Mammary Postnatal Organogenesis

Abstract LB-182: Differential modulation of the PD-1 pathway impacts the anti-tumor activity of CAR T cells

Tumor-infiltrating lymphocytes are dynamically desensitized to antigen but are maintained by homeostatic cytokine

ALLO-715, an Allogeneic BCMA CAR T Therapy Possessing an Off-Switch for the Treatment of Multiple Myeloma

Allogeneic Anti-Bcma CAR-T Cells Show Tumour Specific Killing Against Primary Multiple Myeloma Cells from Different Genomic Sub-Groups

Design and Validation of Inducible TurboCARs with Tunable Induction and Combinatorial Cytokine Signaling

Allogeneic Anti-BCMA CAR T Cells Are Superior to Multiple Myeloma-derived CAR T Cells in Preclinical Studies and May Be Combined with Gamma Secretase Inhibitors

Abstract 4067: Development of tumor-restricted IL-12 with antigen-dependent expression and localized IL-12 activity

Preclinical Evaluation of Allogeneic Anti-Bcma Chimeric Antigen Receptor T Cells with Safety Switch Domains and Lymphodepletion Resistance for the Treatment of Multiple Myeloma

Cxcl12 evolution--subfunctionalization of a ligand through altered interaction with the chemokine receptor

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