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Impact of high-throughput screening in biomedical research

Nature reviews. Drug discovery, 2011-03, Vol.10 (3), p.188-195

2011

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Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug development

Drug discovery today, 2005-11, Vol.10 (21), p.1421-1433

2005

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Novel trends in high-throughput screening

Current opinion in pharmacology, 2009-10, Vol.9 (5), p.580-588

2009

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Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery

Journal of biomolecular screening, 2008-06, Vol.13 (5), p.343-353

2008

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In vitro safety pharmacology profiling : an essential tool for successful drug development

Drug discovery today, 2005-11, Vol.10 (21), p.1421-1433

2005

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Maximising use of in vitro ADMET tools to predict in vivo bioavailability and safety

Expert opinion on drug metabolism & toxicology, 2007-10, Vol.3 (5), p.641-665

2007

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Handbook of Drug Screening

Drug discovery today, 2001-12, Vol.6 (24), p.1266-1266

Bojanic, Dejan

2001

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High-Content Micronucleus Assay in Genotoxicity Profiling: Initial-Stage Development and Some Applications in the Investigative/Lead-Finding Studies in Drug Discovery

Toxicological sciences, 2010-11, Vol.118 (1), p.71-85

2010

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A Novel Membrane Potential-Sensitive Fluorescent Dye Improves Cell-Based Assays for Ion Channels

SLAS discovery, 2002-02, Vol.7 (1), p.79-85

2002

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High-throughput in vitro profiling assays: lessons learnt from experiences at Novartis

Expert opinion on drug metabolism & toxicology, 2006-12, Vol.2 (6), p.823-833

2006

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Assay Development and Screening of Human DGAT1 Inhibitors with an LC/MS-Based Assay: Application of Mass Spectrometry for Large-Scale Primary Screening

Journal of biomolecular screening, 2010-07, Vol.15 (6), p.695-702

2010

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Current trends in high-throughput screening

Assay and drug development technologies, 2008-08, Vol.6 (4), p.491-504

2008

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The combinatorial synthesis of a 30,752-compound library: discovery of SAR around the endothelin antagonist, FR-139,317

Bioorganic & medicinal chemistry letters, 1995-05, Vol.5 (9), p.917-922

1995

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Which aspects of HTS are empirically correlated with downstream success?

Current opinion in drug discovery & development, 2008-05, Vol.11 (3), p.327

2008

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Studies on the pharmacology of rat adipocyte beta-adrenoceptors

Bojanic, Dejan

1984

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Identification and subclassification of rat adipocyte β-adrenoceptors using [formula omitted]

European journal of pharmacology, 1983-09, Vol.93 (3), p.235-243

1983

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Identification and subclassification of rat adipocyte β-adrenoceptors using (±) [125I] cyanopindolol

European journal of pharmacology, 1983-09, Vol.93 (3-4), p.235-243

1983

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Imidazo[2′-3′-:6,5]dipyrido[3,2-b:2′,3′-e]-1,4-diazepines: non-nucleoside HIV-1 reverse transcriptase inhibitors with greater enzyme affinity than nevirapine

Bioorganic & medicinal chemistry letters, 1992-12, Vol.2 (12), p.1745-1750

1992

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Guanine nucleotide and pyrophosphate activate exogenous phosphatidylinositol 4,5-bisphosphate hydrolysis in rat liver plasma membranes

Biochemical and biophysical research communications, 1987-09, Vol.147 (3), p.1088-1094

1987

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Purification of two membrane-derived species of phospholipase C from rabbit brain

Biochemical Society transactions, 1989-02, Vol.17 (1), p.89-90

1989

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Irreversible Antagonism of Beta-Adrenoceptors with Para-Amino-Benzyl-Carazolol Provides Further Evidence for an Atypical Rat Adipocyte Beta-Adrenoceptor

Journal of receptor research, 1984, Vol.4 (1-6), p.21-35

1984

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A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels

Journal of biomolecular screening, 2002-02, Vol.7 (1), p.79

2002

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Cardiac Remodeling Biomarkers as Potential Circulating Markers of Left Ventricular Hypertrophy in Heart Failure with Preserved Ejection Fraction

The Tohoku Journal of Experimental Medicine, 2020, Vol.250(4), pp.233-242

2020

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Double‐blind, randomised, placebo‐controlled trial on the effect of L‐carnitine and L‐acetylcarnitine on sperm parameters in men with idiopathic oligoasthenozoospermia

Andrologia, 2019-07, Vol.51 (6), p.e13267-n/a

2019

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Interaction of thrombophilic SNPs in patients with unexplained infertility—multifactor dimensionality reduction (MDR) model analysis

Journal of assisted reproduction and genetics, 2020-06, Vol.37 (6), p.1449-1458

2020

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Impact of high-throughput screening in biomedical research

Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug development

Novel trends in high-throughput screening

Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery

In vitro safety pharmacology profiling : an essential tool for successful drug development

Maximising use of in vitro ADMET tools to predict in vivo bioavailability and safety

Handbook of Drug Screening

High-Content Micronucleus Assay in Genotoxicity Profiling: Initial-Stage Development and Some Applications in the Investigative/Lead-Finding Studies in Drug Discovery

A Novel Membrane Potential-Sensitive Fluorescent Dye Improves Cell-Based Assays for Ion Channels

High-throughput in vitro profiling assays: lessons learnt from experiences at Novartis

Assay Development and Screening of Human DGAT1 Inhibitors with an LC/MS-Based Assay: Application of Mass Spectrometry for Large-Scale Primary Screening

Current trends in high-throughput screening

The combinatorial synthesis of a 30,752-compound library: discovery of SAR around the endothelin antagonist, FR-139,317

Which aspects of HTS are empirically correlated with downstream success?

Studies on the pharmacology of rat adipocyte beta-adrenoceptors

Identification and subclassification of rat adipocyte β-adrenoceptors using [formula omitted]

Identification and subclassification of rat adipocyte β-adrenoceptors using (±) [125I] cyanopindolol

Imidazo[2′-3′-:6,5]dipyrido[3,2-b:2′,3′-e]-1,4-diazepines: non-nucleoside HIV-1 reverse transcriptase inhibitors with greater enzyme affinity than nevirapine

Guanine nucleotide and pyrophosphate activate exogenous phosphatidylinositol 4,5-bisphosphate hydrolysis in rat liver plasma membranes

Purification of two membrane-derived species of phospholipase C from rabbit brain

Irreversible Antagonism of Beta-Adrenoceptors with Para-Amino-Benzyl-Carazolol Provides Further Evidence for an Atypical Rat Adipocyte Beta-Adrenoceptor

A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels

Cardiac Remodeling Biomarkers as Potential Circulating Markers of Left Ventricular Hypertrophy in Heart Failure with Preserved Ejection Fraction

Double‐blind, randomised, placebo‐controlled trial on the effect of L‐carnitine and L‐acetylcarnitine on sperm parameters in men with idiopathic oligoasthenozoospermia

Interaction of thrombophilic SNPs in patients with unexplained infertility—multifactor dimensionality reduction (MDR) model analysis

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