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NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility

Science (American Association for the Advancement of Science), 2020-06, Vol.368 (6495), p.1132-1135

2020

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C–N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis

Bioconjugate chemistry, 2020-03, Vol.31 (3), p.770-780

2020

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Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

PloS one, 2013-12, Vol.8 (12), p.e83756-e83756

2013

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Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis

Bioconjugate chemistry, 2019-08, Vol.30 (8), p.2209-2215

2019

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A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus

The Journal of biological chemistry, 2004-06, Vol.279 (26), p.27233-27238

2004

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DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors

Communications chemistry, 2023-08, Vol.6 (1), p.164-164, Article 164

2023

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Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (29), p.16782-16789

2020

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Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening

Journal of medicinal chemistry, 2023-02, Vol.66 (3), p.2143-2160

2023

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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (36)

2021

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Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (19), p.e2322934121

2024

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Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries

ACS combinatorial science, 2020-02, Vol.22 (2), p.80-88

2020

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Ascorbate Synthesis Pathway: DUAL ROLE OF ASCORBATE IN BONE HOMEOSTASIS

The Journal of biological chemistry, 2010-06, Vol.285 (25), p.19510-19520

2010

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Reversible male contraception by targeted inhibition of serine/threonine kinase 33

Science (American Association for the Advancement of Science), 2024-05, Vol.384 (6698), p.885-890

2024

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1796-P: A-ß+ Ketosis-Prone Diabetes (KPD) Patients Augment Insulin Response to Arginine but Not to Glucose after Sustained Hyperglycemia

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation

Biochemical and biophysical research communications, 2005-11, Vol.337 (2), p.517-520

2005

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Arginine Metabolism Is Altered in Adults with A-β + Ketosis-Prone Diabetes

The Journal of nutrition, 2018-02, Vol.148 (2), p.185-193

2018

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Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

American journal of physiology. Heart and circulatory physiology, 2012-08, Vol.303 (3), p.H297-H308

2012

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Indian women of childbearing age do not metabolically conserve arginine as do American and Jamaican women

The Journal of nutrition, 2015-05, Vol.145 (5), p.884-892

2015

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The Sorbinil Trap: A Predicted Dead-End Complex Confirms the Mechanism of Aldose Reductase Inhibition

Biochemistry (Easton), 2000-08, Vol.39 (32), p.9967-9974

2000

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Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme

Biochemistry (Easton), 1994-03, Vol.33 (8), p.2021-2032

1994

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Human Aldose Reductase: Rate Constants for a Mechanism Including Interconversion of Ternary Complexes by Recombinant Wild-Type Enzyme

Biochemistry (Easton), 1995-11, Vol.34 (44), p.14356-14365

1995

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An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate

Biochemistry (Easton), 1994-03, Vol.33 (8), p.2011-2020

1994

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Factors Affecting Counteraction by Methylamines of Urea Effects on Aldose Reductase

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (11), p.6517-6522

1999

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Arginine metabolic endotypes in pulmonary arterial hypertension

Pulmonary circulation, 2015-03, Vol.5 (1), p.124-134

2015

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The Alrestatin Double-Decker: Binding of Two Inhibitor Molecules to Human Aldose Reductase Reveals a New Specificity Determinant

Biochemistry (Easton), 1997-12, Vol.36 (51), p.16134-16140

1997

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NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility

C–N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis

Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis

A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus

DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors

Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library

Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening

DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors

Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology

Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries

Ascorbate Synthesis Pathway: DUAL ROLE OF ASCORBATE IN BONE HOMEOSTASIS

Reversible male contraception by targeted inhibition of serine/threonine kinase 33

1796-P: A-ß+ Ketosis-Prone Diabetes (KPD) Patients Augment Insulin Response to Arginine but Not to Glucose after Sustained Hyperglycemia

A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation

Arginine Metabolism Is Altered in Adults with A-β + Ketosis-Prone Diabetes

Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

Indian women of childbearing age do not metabolically conserve arginine as do American and Jamaican women

The Sorbinil Trap: A Predicted Dead-End Complex Confirms the Mechanism of Aldose Reductase Inhibition

Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme

Human Aldose Reductase: Rate Constants for a Mechanism Including Interconversion of Ternary Complexes by Recombinant Wild-Type Enzyme

An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate

Factors Affecting Counteraction by Methylamines of Urea Effects on Aldose Reductase

Arginine metabolic endotypes in pulmonary arterial hypertension

The Alrestatin Double-Decker: Binding of Two Inhibitor Molecules to Human Aldose Reductase Reveals a New Specificity Determinant

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