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The "Perivascular Pump" Driven by Arterial Pulsation is a Powerful Mechanism for the Distribution of Therapeutic Molecules within the Brain

Molecular therapy, 2006-07, Vol.14 (1), p.69-78

2006

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AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS

Neurobiology of disease, 2012-08, Vol.47 (2), p.174-183

2012

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Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson's disease

Journal of neuroscience research, 2010-09, Vol.88 (12), p.2669-2681

2010

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Novel Magnetic Hydroxyapatite Nanoparticles as Non-Viral Vectors for the Glial Cell Line-Derived Neurotrophic Factor Gene

Advanced functional materials, 2010-01, Vol.20 (1), p.67-77

2010

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Mesenchymal stem cells and neuroregeneration in Parkinson's disease

Experimental neurology, 2013-09, Vol.247, p.25-38

2013

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Onset of rosette formation during spontaneous neural differentiation of hESC and hiPSC colonies

Gene, 2014-01, Vol.534 (2), p.400-407

2014

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Reversal of Dopaminergic Degeneration in a Parkinsonian Rat following Micrografting of Human Bone Marrow-Derived Neural Progenitors

Cell transplantation, 2009-01, Vol.18 (7), p.801-814

2009

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Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy

Science (American Association for the Advancement of Science), 1997-02, Vol.275 (5301), p.838-841

1997

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Targeting alpha-synuclein with a microRNA-embedded silencing vector in the rat substantia nigra: Positive and negative effects

Brain research, 2014-03, Vol.1550, p.47-60

2014

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Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function

Cerebral cortex (New York, N.Y. 1991), 2015-11, Vol.25 (11), p.4259-4272

2015

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An alpha-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons

Brain research, 2011-06, Vol.1395, p.94-107

2011

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Motoneurons crave glial cell line-derived neurotrophic factor

Experimental neurology, 2004-12, Vol.190 (2), p.263-275

Bohn, Martha C.

2004

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Silencing of human α-synuclein in vitro and in rat brain using lentiviral-mediated RNAi

Experimental neurology, 2006-04, Vol.198 (2), p.382-390

2006

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A microRNA embedded AAV alpha-synuclein gene silencing vector for dopaminergic neurons

Brain research, 2011-04, Vol.1386, p.15-24

2011

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Inclusion of a portion of the native SNCA 3'UTR reduces toxicity of human S129A SNCA on striatal-projecting dopamine neurons in rat substantia nigra

Developmental neurobiology (Hoboken, N.J.), 2012-06, Vol.72 (6), p.906-917

2012

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Glial Cell Line-Derived Neurotrophic Factor (GDNF) Gene Delivery Protects Dopaminergic Terminals from Degeneration

Experimental neurology, 2001-05, Vol.169 (1), p.83-95

2001

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Hypothalamic IGF-I Gene Therapy Prolongs Estrous Cyclicity and Protects Ovarian Structure in Middle-Aged Female Rats

Endocrinology (Philadelphia), 2013-06, Vol.154 (6), p.2166-2173

2013

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Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of parkinson's disease does not involve activation of caspase-9 and caspase-3

Journal of neuroscience research, 2008-02, Vol.86 (2), p.317-325

2008

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Non-viral delivery of the gene for glial cell line-derived neurotrophic factor to mesenchymal stem cells in vitro via a collagen scaffold

Tissue engineering. Part C, Methods, 2008-09, Vol.14 (3), p.207

2008

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Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects cortical neurons from dying following a traumatic brain injury

Restorative neurology and neuroscience, 2010, Vol.28 (3), p.293

2010

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Delivery of a GDNF Gene into the Substantia Nigra after a Progressive 6-OHDA Lesion Maintains Functional Nigrostriatal Connections

Experimental neurology, 2000-11, Vol.166 (1), p.1-15

2000

Volltextzugriff (PDF)

Behavioral and Cellular Protection of Rat Dopaminergic Neurons by an Adenoviral Vector Encoding Glial Cell Line-Derived Neurotrophic Factor

Experimental neurology, 1998-12, Vol.154 (2), p.261-275

1998

Volltextzugriff (PDF)

Parkinson's Disease: A Neurodegenerative Disease Particularly Amenable to Gene Therapy

Molecular therapy, 2000-06, Vol.1 (6), p.494

Bohn, Martha C

2000

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A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo

Experimental neurology, 2005-02, Vol.191, p.S80-S94

2005

Volltextzugriff (PDF)

Parkinson's Disease: A Neurodegenerative Disease Particularly Amenable to Gene Therapy

Molecular therapy, 2000-06, Vol.1 (6), p.494-496

Bohn, Martha C.

2000

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The "Perivascular Pump" Driven by Arterial Pulsation is a Powerful Mechanism for the Distribution of Therapeutic Molecules within the Brain

AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS

Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson's disease

Novel Magnetic Hydroxyapatite Nanoparticles as Non-Viral Vectors for the Glial Cell Line-Derived Neurotrophic Factor Gene

Mesenchymal stem cells and neuroregeneration in Parkinson's disease

Onset of rosette formation during spontaneous neural differentiation of hESC and hiPSC colonies

Reversal of Dopaminergic Degeneration in a Parkinsonian Rat following Micrografting of Human Bone Marrow-Derived Neural Progenitors

Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy

Targeting alpha-synuclein with a microRNA-embedded silencing vector in the rat substantia nigra: Positive and negative effects

Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function

An alpha-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons

Motoneurons crave glial cell line-derived neurotrophic factor

Silencing of human α-synuclein in vitro and in rat brain using lentiviral-mediated RNAi

A microRNA embedded AAV alpha-synuclein gene silencing vector for dopaminergic neurons

Inclusion of a portion of the native SNCA 3'UTR reduces toxicity of human S129A SNCA on striatal-projecting dopamine neurons in rat substantia nigra

Glial Cell Line-Derived Neurotrophic Factor (GDNF) Gene Delivery Protects Dopaminergic Terminals from Degeneration

Hypothalamic IGF-I Gene Therapy Prolongs Estrous Cyclicity and Protects Ovarian Structure in Middle-Aged Female Rats

Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of parkinson's disease does not involve activation of caspase-9 and caspase-3

Non-viral delivery of the gene for glial cell line-derived neurotrophic factor to mesenchymal stem cells in vitro via a collagen scaffold

Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects cortical neurons from dying following a traumatic brain injury

Delivery of a GDNF Gene into the Substantia Nigra after a Progressive 6-OHDA Lesion Maintains Functional Nigrostriatal Connections

Behavioral and Cellular Protection of Rat Dopaminergic Neurons by an Adenoviral Vector Encoding Glial Cell Line-Derived Neurotrophic Factor

Parkinson's Disease: A Neurodegenerative Disease Particularly Amenable to Gene Therapy

A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo

Parkinson's Disease: A Neurodegenerative Disease Particularly Amenable to Gene Therapy

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