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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Science (American Association for the Advancement of Science), 1999-12, Vol.286 (5449), p.2495-2498

1999

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Desensitization of G protein-coupled receptors and neuronal functions

Annual review of neuroscience, 2004-01, Vol.27 (1), p.107-144

2004

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Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Molecular pharmacology, 2004-07, Vol.66 (1), p.106-112

2004

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Glutamatergic Modulation of Hyperactivity in Mice Lacking the Dopamine Transporter

Proceedings of the National Academy of Sciences - PNAS, 2001-09, Vol.98 (20), p.11047-11054

2001

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Potentiated Opioid Analgesia in Norepinephrine Transporter Knock-Out Mice

The Journal of neuroscience, 2000-12, Vol.20 (24), p.9040-9045

2000

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An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization

Molecular pharmacology, 2007-02, Vol.71 (2), p.549-557

2007

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Mitogenic signaling via endogenous κ-opioid receptors in C6 glioma cells : Evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade

Journal of neurochemistry, 2000-02, Vol.74 (2), p.564-573

2000

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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Neuron (Cambridge, Mass.), 1999-12, Vol.24 (4), p.1029-1036

1999

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μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Nature (London), 2000-12, Vol.408 (6813), p.720-723

2000

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Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in beta Arrestin-2 Knock-Out Mice

The Journal of neuroscience, 2002-12, Vol.22 (23), p.10494-10500

2002

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Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice

The Journal of neuroscience, 2003-11, Vol.23 (32), p.10265-10273

2003

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Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice

Neuron (Cambridge, Mass.), 2003-04, Vol.38 (2), p.291-303

2003

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μ‐Opioid Agonist Inhibition of κ‐Opioid Receptor‐Stimulated Extracellular Signal‐Regulated Kinase Phosphorylation Is Dynamin‐Dependent in C6 Glioma Cells

Journal of neurochemistry, 2000-02, Vol.74 (2), p.574-581

2000

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Sustained Elevation of Extracellular Dopamine Causes Motor Dysfunction and Selective Degeneration of Striatal GABAergic Neurons

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (19), p.11035-11040

2003

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Drosophila CG8422 encodes a functional diuretic hormone receptor

Journal of experimental biology, 2004-02, Vol.207 (Pt 5), p.743-748

2004

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Identification of Drosophila Neuropeptide Receptors by G Protein-coupled Receptors-β-Arrestin2 Interactions

The Journal of biological chemistry, 2003-12, Vol.278 (52), p.52172-52178

2003

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Crystal Structure of the Human Cannabinoid Receptor CB2

Cell, 2019-01, Vol.176 (3), p.459-467.e13

2019

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Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Science signaling, 2016-11, Vol.9 (456), p.ra117

2016

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Apparent Loss-of-Function Mutant GPCRs Revealed as Constitutively Desensitized Receptors

Biochemistry (Easton), 2002-10, Vol.41 (40), p.11981-11989

2002

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Evidence for κ‐ and μ‐Opioid Receptor Expression in C6 Glioma Cells

Journal of neurochemistry, 1998-05, Vol.70 (5), p.1819-1825

1998

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Mu opioid receptor regulation and opiate responsiveness

The AAPS journal, 2005-10, Vol.7 (3), p.E587-E591

2005

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Requirement of Receptor Internalization for Opioid Stimulation of Mitogen-Activated Protein Kinase: Biochemical and Immunofluorescence Confocal Microscopic Evidence

The Journal of neuroscience, 1999-01, Vol.19 (1), p.56-63

1999

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The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics

Neuropharmacology, 2011-01, Vol.60 (1), p.58-65

2011

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κ‐Opioid receptor binding varies inversely with tumor grade in human gliomas

Cancer, 1998-12, Vol.83 (12), p.2561-2566

1998

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Morphine side effects in beta-arrestin 2 knockout mice

The Journal of pharmacology and experimental therapeutics, 2005-09, Vol.314 (3), p.1195

2005

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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Desensitization of G protein-coupled receptors and neuronal functions

Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Glutamatergic Modulation of Hyperactivity in Mice Lacking the Dopamine Transporter

Potentiated Opioid Analgesia in Norepinephrine Transporter Knock-Out Mice

An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization

Mitogenic signaling via endogenous κ-opioid receptors in C6 glioma cells : Evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in beta Arrestin-2 Knock-Out Mice

Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice

Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice

μ‐Opioid Agonist Inhibition of κ‐Opioid Receptor‐Stimulated Extracellular Signal‐Regulated Kinase Phosphorylation Is Dynamin‐Dependent in C6 Glioma Cells

Sustained Elevation of Extracellular Dopamine Causes Motor Dysfunction and Selective Degeneration of Striatal GABAergic Neurons

Drosophila CG8422 encodes a functional diuretic hormone receptor

Identification of Drosophila Neuropeptide Receptors by G Protein-coupled Receptors-β-Arrestin2 Interactions

Crystal Structure of the Human Cannabinoid Receptor CB2

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Apparent Loss-of-Function Mutant GPCRs Revealed as Constitutively Desensitized Receptors

Evidence for κ‐ and μ‐Opioid Receptor Expression in C6 Glioma Cells

Mu opioid receptor regulation and opiate responsiveness

Requirement of Receptor Internalization for Opioid Stimulation of Mitogen-Activated Protein Kinase: Biochemical and Immunofluorescence Confocal Microscopic Evidence

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics

κ‐Opioid receptor binding varies inversely with tumor grade in human gliomas

Morphine side effects in beta-arrestin 2 knockout mice

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