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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

Scientific reports, 2020-03, Vol.10 (1), p.5627, Article 5627

2020

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Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

Scientific reports, 2020-07, Vol.10 (1), p.11884-11884, Article 11884

2020

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Altered Synaptic Plasticity and Memory Formation in Nitric Oxide Synthase Inhibitor-Treated Rats

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (19), p.9191-9194

1993

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Inhibitory Profile of Clozapine AT CiPA Cardiac Ion Channels

Biophysical journal, 2020-02, Vol.118 (3), p.590a-590a

Bohme, Georg Andrees

2020

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Validation of an Automated Patch-Clamp Screening Assay on Human Kir2.1 Cardiac Ion Channels

Biophysical journal, 2018-02, Vol.114 (3), p.311a-311a

2018

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Cannabidiol inhibits multiple cardiac ion channels and shortens ventricular action potential duration in vitro

European journal of pharmacology, 2020-11, Vol.886, p.173542, Article 173542

2020

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Impaired Long-Term Potentiation Induction in Dentate Gyrus of Calretinin-Deficient Mice

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (19), p.10415-10420

1997

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Multichannel inhibitory profile of (−)-Cannabidiol on cardiac ion channels

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106718, Article 106718

2020

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Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

Human molecular genetics, 2003-09, Vol.12 (18), p.2277-2291

2003

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Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury

British journal of pharmacology, 1999-05, Vol.127 (2), p.546-552

1999

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Evidence for an endogenous cholecystokininergic balance in social memory

Neuroreport, 1992-10, Vol.3 (10), p.929-932

1992

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Antisense Oligodeoxynucleotide to Inducible Nitric Oxide Synthase Protects Against Transient Focal Cerebral Ischemia-Induced Brain Injury

Journal of cerebral blood flow and metabolism, 2001-01, Vol.21 (1), p.15-21

2001

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A Role for Nitric Oxide in Long-term Potentiation

The European journal of neuroscience, 1992-05, Vol.4 (5), p.420-424

1992

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9-Carboxymethyl-5H, 10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): Selective anticonvulsive and neuroprotective AMPA antagonist

Bioorganic & medicinal chemistry, 2002-05, Vol.10 (5), p.1627-1637

2002

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Effect of Chronic Treatment with Riluzole on the Nigrostriatal Dopaminergic System in Weaver Mutant Mice

Experimental neurology, 2002-07, Vol.176 (1), p.247-253

2002

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Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit

The Journal of pharmacology and experimental therapeutics, 2005-02, Vol.312 (2), p.619

2005

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Indeno[1,2-b]pyrazin-2,3-diones: A New Class of Antagonists at the Glycine Site of the NMDA Receptor with Potent in Vivo Activity

Journal of medicinal chemistry, 2000-06, Vol.43 (12), p.2371-2381

2000

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Riluzole reduces hyperactivity of subthalamic neurons induced by unilateral 6-OHDA lesion in the rat brain

Movement disorders, 2001-11, Vol.16 (6), p.1110-1114

2001

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In vitro and in vivo characterization of TC-1827, a novel brain α4β2 nicotinic receptor agonist with pro-cognitive activity

Drug development research, 2004-05, Vol.62 (1), p.26-40

2004

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4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives: highly potent and selective AMPA receptors antagonists with in vivo activity

Bioorganic & medicinal chemistry letters, 2000-05, Vol.10 (10), p.1133

2000

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9-Carboxymethyl-5 H ,10 H -imidazo[1,2- a ]indeno[1,2- e ]pyrazin-4-one-2-carbocylic Acid (RPR117824): Selective Anticonvulsive and Neuroprotective AMPA Antagonist

Bioorganic & medicinal chemistry, 2002-05, Vol.10 (5), p.1627-1637

2002

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Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.127-132

2001

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Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2- a]indeno[1,2- e]pyrazin-8- and -9-carboxylic (acetic) acid AMPA antagonists

Bioorganic & medicinal chemistry letters, 2000-12, Vol.10 (24), p.2749-2754

2000

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Synthesis of anticonvulsive AMPA antagonists: 4-Oxo-10-substituted-imidazo[1,2- a]indeno[1,2- e]pyrazin-2-carboxylic acid derivatives

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (9), p.1205-1210

2001

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8-Methylureido-4,5-dihydro-4-oxo-10H-imidazo[1,2-a]indeno-[1,2-e]pyrazines : Highly potent in vivo AMPA antagonists

Bioorganic & medicinal chemistry letters, 2000-03, Vol.10 (6), p.591-596

2000

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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

Altered Synaptic Plasticity and Memory Formation in Nitric Oxide Synthase Inhibitor-Treated Rats

Inhibitory Profile of Clozapine AT CiPA Cardiac Ion Channels

Validation of an Automated Patch-Clamp Screening Assay on Human Kir2.1 Cardiac Ion Channels

Cannabidiol inhibits multiple cardiac ion channels and shortens ventricular action potential duration in vitro

Impaired Long-Term Potentiation Induction in Dentate Gyrus of Calretinin-Deficient Mice

Multichannel inhibitory profile of (−)-Cannabidiol on cardiac ion channels

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury

Evidence for an endogenous cholecystokininergic balance in social memory

Antisense Oligodeoxynucleotide to Inducible Nitric Oxide Synthase Protects Against Transient Focal Cerebral Ischemia-Induced Brain Injury

A Role for Nitric Oxide in Long-term Potentiation

9-Carboxymethyl-5H, 10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): Selective anticonvulsive and neuroprotective AMPA antagonist

Effect of Chronic Treatment with Riluzole on the Nigrostriatal Dopaminergic System in Weaver Mutant Mice

Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit

Indeno[1,2-b]pyrazin-2,3-diones: A New Class of Antagonists at the Glycine Site of the NMDA Receptor with Potent in Vivo Activity

Riluzole reduces hyperactivity of subthalamic neurons induced by unilateral 6-OHDA lesion in the rat brain

In vitro and in vivo characterization of TC-1827, a novel brain α4β2 nicotinic receptor agonist with pro-cognitive activity

4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives: highly potent and selective AMPA receptors antagonists with in vivo activity

9-Carboxymethyl-5 H ,10 H -imidazo[1,2- a ]indeno[1,2- e ]pyrazin-4-one-2-carbocylic Acid (RPR117824): Selective Anticonvulsive and Neuroprotective AMPA Antagonist

Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action

Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2- a]indeno[1,2- e]pyrazin-8- and -9-carboxylic (acetic) acid AMPA antagonists

Synthesis of anticonvulsive AMPA antagonists: 4-Oxo-10-substituted-imidazo[1,2- a]indeno[1,2- e]pyrazin-2-carboxylic acid derivatives

8-Methylureido-4,5-dihydro-4-oxo-10H-imidazo[1,2-a]indeno-[1,2-e]pyrazines : Highly potent in vivo AMPA antagonists

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