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A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

Toxicology and applied pharmacology, 2013-04, Vol.268 (1), p.1-16

2013

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Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail

Frontiers in pharmacology, 2016-11, Vol.7, p.443-443

2016

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Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs

PloS one, 2016-07, Vol.11 (7), p.e0159431

2016

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Erratum to: Pathway reporter genes define molecular phenotypes of human cells

BMC genomics, 2017-05, Vol.18 (1), p.337-337, Article 337

2017

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Discriminating Different Classes of Toxicants by Transcript Profiling

Environmental health perspectives, 2004-08, Vol.112 (12), p.1236-1248

2004

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Phytanic acid, a natural peroxisome proliferator‐activated receptor agonist, regulates glucose metabolism in rat primary hepatocytes

The FASEB journal, 2002-05, Vol.16 (7), p.718-720

2002

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In Vitro Assessment of the Hepatotoxicity Potential of Therapeutic Oligonucleotides

Methods in molecular biology (Clifton, N.J.), 2019, Vol.2036, p.249

2019

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Gene Expression Analysis of the Hepatotoxicant Methapyrilene in Primary Rat Hepatocytes: An Interlaboratory Study

Environmental health perspectives, 2006-01, Vol.114 (1), p.92-99

2006

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Modulation of Gene and Protein Expression by Carbon Tetrachloride in the Rat Liver

Toxicology and applied pharmacology, 2002-08, Vol.183 (1), p.71-80

2002

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Application of lipid peroxidation products as biomarkers for flutamide-induced oxidative stress in vitro

Toxicology letters, 2015-11, Vol.238 (3), p.53-59

2015

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Pathway reporter genes define molecular phenotypes of human cells

BMC genomics, 2015-04, Vol.16 (1), p.342-342, Article 342

2015

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Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species

Biochemical pharmacology, 2000-09, Vol.60 (5), p.615-623

2000

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Author Correction: A novel antibiotic class targeting the lipopolysaccharide transporter

Nature (London), 2024-07, Vol.631 (8022), p.E17-E17

2024

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Biomarkers of Flutamide-Bioactivation and Oxidative Stress In Vitro and In Vivo

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.560-569

2016

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Gene Expression in Two Hepatic Cell Lines, Cultured Primary Hepatocytes, and Liver Slices Compared to the in Vivo Liver Gene Expression in Rats: Possible Implications for Toxicogenomics Use of in Vitro Systems

Toxicological sciences, 2003-06, Vol.73 (2), p.386-402

2003

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Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator

Toxicological sciences, 2020-08, Vol.176 (2), p.329-342

2020

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Simultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus Inhibitor

The Journal of pharmacology and experimental therapeutics, 2018-05, Vol.365 (2), p.237-248

2018

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Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro

Toxicology (Amsterdam), 2017-03, Vol.379, p.48-61

2017

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Discriminating Different Classes of Toxicants by Transcript Profiling

Environmental health perspectives, 2004-08, Vol.112 (12), p.1236-1248

2004

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Effect of GLP1R agonists taspoglutide and liraglutide on primary thyroid C-cells from rodent and man

Journal of molecular endocrinology, 2013-06, Vol.50 (3), p.325-336

2013

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Assessment of hepatotoxic liabilities by transcript profiling

Toxicology and applied pharmacology, 2005-09, Vol.207 (2), p.161-170

2005

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Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development

Journal of biochemical and molecular toxicology, 2011-05, Vol.25 (3), p.183-194

2011

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In vitro assessments of hepatic toxicity using the xCELLigence real-time cell analyzer

Toxicology letters, 2009-09, Vol.189, p.S74-S75

2009

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In vitro investigation on the impact of the surface-active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam

Biopharmaceutics & drug disposition, 2004-01, Vol.25 (1), p.37-49

2004

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A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail

Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs

Erratum to: Pathway reporter genes define molecular phenotypes of human cells

Discriminating Different Classes of Toxicants by Transcript Profiling

Phytanic acid, a natural peroxisome proliferator‐activated receptor agonist, regulates glucose metabolism in rat primary hepatocytes

In Vitro Assessment of the Hepatotoxicity Potential of Therapeutic Oligonucleotides

Gene Expression Analysis of the Hepatotoxicant Methapyrilene in Primary Rat Hepatocytes: An Interlaboratory Study

A novel antibiotic class targeting the lipopolysaccharide transporter

Modulation of Gene and Protein Expression by Carbon Tetrachloride in the Rat Liver

Application of lipid peroxidation products as biomarkers for flutamide-induced oxidative stress in vitro

Pathway reporter genes define molecular phenotypes of human cells

Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species

Author Correction: A novel antibiotic class targeting the lipopolysaccharide transporter

Biomarkers of Flutamide-Bioactivation and Oxidative Stress In Vitro and In Vivo

Gene Expression in Two Hepatic Cell Lines, Cultured Primary Hepatocytes, and Liver Slices Compared to the in Vivo Liver Gene Expression in Rats: Possible Implications for Toxicogenomics Use of in Vitro Systems

Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator

Simultaneous Assessment of Clearance, Metabolism, Induction, and Drug-Drug Interaction Potential Using a Long-Term In Vitro Liver Model for a Novel Hepatitis B Virus Inhibitor

Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro

Discriminating Different Classes of Toxicants by Transcript Profiling

Effect of GLP1R agonists taspoglutide and liraglutide on primary thyroid C-cells from rodent and man

Assessment of hepatotoxic liabilities by transcript profiling

Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development

In vitro assessments of hepatic toxicity using the xCELLigence real-time cell analyzer

In vitro investigation on the impact of the surface-active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam

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