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Inhibition of inducible nitric oxide synthase in respiratory diseases

Biochemical Society transactions, 2009-08, Vol.37 (Pt 4), p.886-891

2009

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Imidazoquinolinone, Imidazopyridine, and Isoquinolindione Derivatives as Novel and Potent Inhibitors of the Poly(ADP-ribose) Polymerase (PARP): A Comparison with Standard PARP Inhibitors

Molecular pharmacology, 2008-12, Vol.74 (6), p.1587-1598

2008

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The Inhibitory Potency and Selectivity of Arginine Substrate Site Nitric-Oxide Synthase Inhibitors Is Solely Determined by Their Affinity toward the Different Isoenzymes

Molecular pharmacology, 2000-11, Vol.58 (5), p.1026-1034

2000

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The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase

Molecular pharmacology, 2006-01, Vol.69 (1), p.328

2006

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BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase

Molecular pharmacology, 2008-04, Vol.73 (4), p.1244-1253

2008

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Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock

Thrombosis and haemostasis, 2006-04, Vol.95 (4), p.720-727

2006

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In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase

The Journal of pharmacology and experimental therapeutics, 2006-04, Vol.317 (1), p.181

2006

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Characterization of the Dexniguldipine Binding Site in the Multidrug Resistance-Related Transport Protein P-Glycoprotein by Photoaffinity Labeling and Mass Spectrometry

Molecular pharmacology, 2002-06, Vol.61 (6), p.1366-1376

2002

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IT-Weiterbildung mit Erfolg: Karriereplaner für IT-Fachkräfte. 1. Aufl

2002

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Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4228-4232

2011

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BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3 H -imidazo[4,5- b ]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase

Molecular pharmacology, 2008-04, Vol.73 (4), p.1244-1253

2008

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The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3 H -imidazo[4,5- b ]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase

Molecular pharmacology, 2006-01, Vol.69 (1), p.328-337

2006

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O34. Potent and highly selective inhibition of the inducible nitric oxide synthase in vitro and in vivo by the novel imidazopyridine BYK191023

Nitric oxide, 2006-06, Vol.14 (4), p.11-11

2006

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In Vivo Characterization of the Novel Imidazopyridine BYK191023 [2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3 H -imidazo[4,5- b ]pyridine], a Potent and Highly Selective Inhibitor of Inducible Nitric-Oxide Synthase

The Journal of pharmacology and experimental therapeutics, 2006-04, Vol.317 (1), p.181-187

2006

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O66. The highly selective iNOS inhibitor BYK402750 exerts potent anti-inflammatory effects in a mouse model of cigarette smoke-induced inflammation

Nitric oxide, 2008, Vol.19, p.35-35

2008

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The adrenoceptor agonist, SDZ NVI 085, discriminates between α1A- and α1B-adrenoceptor subtypes in vas deferens, kidney and aorta of the rat

European journal of pharmacology, 1992-12, Vol.224 (2), p.125-136

1992

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Vasodilatation elicited by 5-HT1A receptor agonists in constant-pressore-perfused rat kidney is mediated by blockade of α1A-adrenoceptors

European journal of pharmacology, 1991-09, Vol.202 (1), p.33-44

1991

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The Specific Bisindolylmaleimide PKC-Inhibitor GF 109203X Efficiently Modulates MRP-Associated Multiple Drug Resistance

Biochemical and biophysical research communications, 1995-01, Vol.206 (1), p.119-126

1995

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In vitro and in vivo uroselectivity of B8805-033, an antagonist with high affinity at prostatic α 1A - vs. α 1B - and α 1D -adrenoceptors

Naunyn-Schmiedeberg's archives of pharmacology, 2001-05, Vol.363 (6), p.649-662

2001

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Mechanism of action of dexniguldipine-HCl (B8509-035), a new potent modulator of multidrug resistance

Biochemical pharmacology, 1995-03, Vol.49 (5), p.603-609

1995

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Dexniguldipine-HCl is a potent allosteric inhibitor of [ 3H]vinblastine binding to P-glycoprotein of CCRF ADR 5000 cells

European journal of pharmacology, 1994-12, Vol.288 (1), p.105-114

1994

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B9209-005, an azido derivative of the chemosensitizer dexniguldipine-HCl, photolabels P-glycoprotein

Molecular pharmacology, 1995-07, Vol.48 (1), p.21

1995

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Sensitivity Studies for Main Steam Line Break Exercises 2 and 3 with RELAP5/PANBOX

Nuclear technology, 2003-05, Vol.142 (2), p.137-145

2003

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Interaction of cytostatics and chemosensitizers with the dexniguldipine binding site on P-glycoprotein

European journal of pharmacology, 1996-01, Vol.295 (2), p.253-260

1996

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Interactions of vasopressin agonists and antagonists with membrane receptors

European journal of pharmacology, 1984-04, Vol.100 (1), p.47-58

1984

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Inhibition of inducible nitric oxide synthase in respiratory diseases

Imidazoquinolinone, Imidazopyridine, and Isoquinolindione Derivatives as Novel and Potent Inhibitors of the Poly(ADP-ribose) Polymerase (PARP): A Comparison with Standard PARP Inhibitors

The Inhibitory Potency and Selectivity of Arginine Substrate Site Nitric-Oxide Synthase Inhibitors Is Solely Determined by Their Affinity toward the Different Isoenzymes

The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase

BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase

Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock

In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase

Characterization of the Dexniguldipine Binding Site in the Multidrug Resistance-Related Transport Protein P-Glycoprotein by Photoaffinity Labeling and Mass Spectrometry

IT-Weiterbildung mit Erfolg: Karriereplaner für IT-Fachkräfte. 1. Aufl

Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights

BYK191023 (2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3 H -imidazo[4,5- b ]pyridine) Is an NADPH- and Time-Dependent Irreversible Inhibitor of Inducible Nitric-Oxide Synthase

The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3 H -imidazo[4,5- b ]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase

O34. Potent and highly selective inhibition of the inducible nitric oxide synthase in vitro and in vivo by the novel imidazopyridine BYK191023

In Vivo Characterization of the Novel Imidazopyridine BYK191023 [2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3 H -imidazo[4,5- b ]pyridine], a Potent and Highly Selective Inhibitor of Inducible Nitric-Oxide Synthase

O66. The highly selective iNOS inhibitor BYK402750 exerts potent anti-inflammatory effects in a mouse model of cigarette smoke-induced inflammation

The adrenoceptor agonist, SDZ NVI 085, discriminates between α1A- and α1B-adrenoceptor subtypes in vas deferens, kidney and aorta of the rat

Vasodilatation elicited by 5-HT1A receptor agonists in constant-pressore-perfused rat kidney is mediated by blockade of α1A-adrenoceptors

The Specific Bisindolylmaleimide PKC-Inhibitor GF 109203X Efficiently Modulates MRP-Associated Multiple Drug Resistance

In vitro and in vivo uroselectivity of B8805-033, an antagonist with high affinity at prostatic α 1A - vs. α 1B - and α 1D -adrenoceptors

Mechanism of action of dexniguldipine-HCl (B8509-035), a new potent modulator of multidrug resistance

Dexniguldipine-HCl is a potent allosteric inhibitor of [ 3H]vinblastine binding to P-glycoprotein of CCRF ADR 5000 cells

B9209-005, an azido derivative of the chemosensitizer dexniguldipine-HCl, photolabels P-glycoprotein

Sensitivity Studies for Main Steam Line Break Exercises 2 and 3 with RELAP5/PANBOX

Interaction of cytostatics and chemosensitizers with the dexniguldipine binding site on P-glycoprotein

Interactions of vasopressin agonists and antagonists with membrane receptors

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