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MicroRNA-1 Negatively Regulates Expression of the Hypertrophy-Associated Calmodulin and Mef2a Genes

Molecular and Cellular Biology, 2009-04, Vol.29 (8), p.2193-2204

2009

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Dolaflexin: A Novel Antibody-Drug Conjugate Platform Featuring High Drug Loading and a Controlled Bystander Effect

Molecular cancer therapeutics, 2021-05, Vol.20 (5), p.885-895

2021

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The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b

Molecular cancer therapeutics, 2021-05, Vol.20 (5), p.896-905

2021

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A Polymer-Based Antibody-Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (16), p.3365-3372

2015

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Development of a Novel DNA Mono-alkylator Platform for Antibody-Drug Conjugates

Molecular cancer therapeutics, 2024-04, Vol.23 (4), p.541-551

2024

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Discovery of novel polyamide-pyrrolobenzodiazepine hybrids for antibody-drug conjugates

Bioorganic & medicinal chemistry letters, 2022-09, Vol.72, p.128876-128876, Article 128876

2022

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Activated Vitamin D Attenuates Left Ventricular Abnormalities Induced by Dietary Sodium in Dahl Salt-Sensitive Animals

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (43), p.16810-16815

2007

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Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality

The Journal of experimental medicine, 2006-06, Vol.203 (6), p.1447-1458

2006

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Gata4 Is Required for Maintenance of Postnatal Cardiac Function and Protection from Pressure Overload-Induced Heart Failure

Proceedings of the National Academy of Sciences - PNAS, 2006-09, Vol.103 (39), p.14471-14476

2006

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Clonally Expanded mtDNA Point Mutations are Abundant in Individual Cells of Human Tissues

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (8), p.5521-5526

2002

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High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

Nature genetics, 2001-06, Vol.28 (2), p.147-150

2001

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Overexpression of HAX-1 Protects Cardiac Myocytes From Apoptosis Through Caspase-9 Inhibition

Circulation research, 2006-08, Vol.99 (4), p.415-423

2006

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Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia

Arteriosclerosis, thrombosis, and vascular biology, 2006-04, Vol.26 (4), p.787-793

2006

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Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes

American journal of physiology. Heart and circulatory physiology, 2007-07, Vol.293 (1), p.H829-H835

2007

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Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms

Annals of the New York Academy of Sciences, 2002-04, Vol.959 (1), p.434-447

2002

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Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats

Vascular pharmacology, 2009-11, Vol.51 (5), p.337-343

2009

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Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process?

Mechanisms of ageing and development, 2003, Vol.124 (1), p.49-53

2003

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Abstract B119: Relationship of NaPi2b expression and efficacy of XMT-1536, a NaPi2b targeting antibody-drug conjugate (ADC), in an unselected panel of human primary ovarian mouse xenograft models

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B119-B119

2018

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Does Intranasal Application of Zinc Sulfate Produce Anosmia in the Rat?

Behavioral neuroscience, 2000-08, Vol.114 (4), p.814-829

2000

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Abstract 48: Non-clinical pharmacokinetics of XMT-1522, a HER2 targeting auristatin-based antibody drug conjugate

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.48-48

2017

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Synergy of an anti-HER2 ADC TAK-522 (XMT-1522) in combination with anti-PD1 monoclonal antibody (mAb) in a syngeneic breast cancer model expressing human HER2

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.122-122.29

2018

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Delivering More Payload (High DAR ADCs)

Innovations for Next-Generation Antibody-Drug Conjugates, 2018, p.215-240

2018

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Abstract 2670: Combination of anti-HER2 ADC XMT-1522 and checkpoint inhibitor pembrolizumab for treatment of NSCLC in preclinical models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2670-2670

2017

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Abstract 754: Unique pharmacologic properties of Dolaflexin-based ADCs—a controlled bystander effect

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.754-754

2018

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Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury

Nature medicine, 2003-02, Vol.9 (2), p.183-190

2003

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MicroRNA-1 Negatively Regulates Expression of the Hypertrophy-Associated Calmodulin and Mef2a Genes

Dolaflexin: A Novel Antibody-Drug Conjugate Platform Featuring High Drug Loading and a Controlled Bystander Effect

The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b

A Polymer-Based Antibody-Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy

Development of a Novel DNA Mono-alkylator Platform for Antibody-Drug Conjugates

Discovery of novel polyamide-pyrrolobenzodiazepine hybrids for antibody-drug conjugates

Activated Vitamin D Attenuates Left Ventricular Abnormalities Induced by Dietary Sodium in Dahl Salt-Sensitive Animals

Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality

Gata4 Is Required for Maintenance of Postnatal Cardiac Function and Protection from Pressure Overload-Induced Heart Failure

Clonally Expanded mtDNA Point Mutations are Abundant in Individual Cells of Human Tissues

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

Overexpression of HAX-1 Protects Cardiac Myocytes From Apoptosis Through Caspase-9 Inhibition

Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia

Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes

Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms

Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats

Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process?

Abstract B119: Relationship of NaPi2b expression and efficacy of XMT-1536, a NaPi2b targeting antibody-drug conjugate (ADC), in an unselected panel of human primary ovarian mouse xenograft models

Does Intranasal Application of Zinc Sulfate Produce Anosmia in the Rat?

Abstract 48: Non-clinical pharmacokinetics of XMT-1522, a HER2 targeting auristatin-based antibody drug conjugate

Synergy of an anti-HER2 ADC TAK-522 (XMT-1522) in combination with anti-PD1 monoclonal antibody (mAb) in a syngeneic breast cancer model expressing human HER2

Delivering More Payload (High DAR ADCs)

Abstract 2670: Combination of anti-HER2 ADC XMT-1522 and checkpoint inhibitor pembrolizumab for treatment of NSCLC in preclinical models

Abstract 754: Unique pharmacologic properties of Dolaflexin-based ADCs—a controlled bystander effect

Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury

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