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Cancer Cell Lines for Drug Discovery and Development

Cancer research (Chicago, Ill.), 2014-05, Vol.74 (9), p.2377-2384

2014

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Cancer stem cells from colorectal cancer-derived cell lines

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3722-3727

2010

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Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers

Proceedings of the National Academy of Sciences - PNAS, 2016-04, Vol.113 (15), p.E2162-E2171

2016

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Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

Cancer research (Chicago, Ill.), 2014-06, Vol.74 (12), p.3238-3247

2014

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GMMchi: gene expression clustering using Gaussian mixture modeling

BMC bioinformatics, 2022-11, Vol.23 (1), p.457-457, Article 457

2022

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CDX1–microRNA-215 axis regulates colorectal cancer stem cell differentiation

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (13), p.E1550-E1558

2015

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Analysis of P53 Mutations and Their Expression in 56 Colorectal Cancer Cell Lines

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (4), p.976-981

2006

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Genotypic and Phenotypic Characteristics of Hereditary Colorectal Cancer

Annals of Coloproctolgy, 2021, 37(6), , pp.368-381

2021

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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

Cell reports (Cambridge), 2022-03, Vol.38 (10), p.110493, Article 110493

2022

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Genetics of the human face: Identification of large-effect single gene variants

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (4), p.E676-E685

2018

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Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2

Cell reports (Cambridge), 2023-06, Vol.42 (6), p.112601-112601, Article 112601

2023

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Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4382-4387

2011

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Stem Cell Differentiation and Lumen Formation in Colorectal Cancer Cell Lines and Primary Tumors

Cancer research (Chicago, Ill.), 2013-09, Vol.73 (18), p.5798-5809

2013

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Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays

The Journal of pathology, 2014-09, Vol.234 (1), p.34-45

2014

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Adult stem cell activity in naked mole rats for long-term tissue maintenance

Nature communications, 2023-12, Vol.14 (1), p.8484-8484, Article 8484

2023

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Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (10), p.4008-4013

2007

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Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes

eLife, 2022-09, Vol.11

2022

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Single-molecule DNA-mapping and whole-genome sequencing of individual cells

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (44), p.11192-11197

2018

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Multigene amplification and massively parallel sequencing for cancer mutation discovery

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (22), p.9387-9392

2007

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Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (32), p.18924-18933

2020

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Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (51), p.21046-21051

2012

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Cancer genetics: colorectal cancer as a model

Journal of human genetics, 2006-05, Vol.51 (5), p.391-396

Bodmer, Walter F

2006

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Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance

Proceedings of the National Academy of Sciences - PNAS, 2024-03, Vol.121 (13), p.e2319055121-e2319055121

2024

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Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.1936-1941

2009

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Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1

The Journal of pathology, 2019-03, Vol.247 (3), p.293-304

2019

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Cancer Cell Lines for Drug Discovery and Development

Cancer stem cells from colorectal cancer-derived cell lines

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

GMMchi: gene expression clustering using Gaussian mixture modeling

CDX1–microRNA-215 axis regulates colorectal cancer stem cell differentiation

Analysis of P53 Mutations and Their Expression in 56 Colorectal Cancer Cell Lines

Genotypic and Phenotypic Characteristics of Hereditary Colorectal Cancer

CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

Genetics of the human face: Identification of large-effect single gene variants

Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2

Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells

Stem Cell Differentiation and Lumen Formation in Colorectal Cancer Cell Lines and Primary Tumors

Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays

Adult stem cell activity in naked mole rats for long-term tissue maintenance

Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes

Single-molecule DNA-mapping and whole-genome sequencing of individual cells

Multigene amplification and massively parallel sequencing for cancer mutation discovery

Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel

Cancer genetics: colorectal cancer as a model

Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance

Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1

Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1

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