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Human organoid cultures: transformative new tools for human virus studies

Current opinion in virology, 2018-04, Vol.29, p.79-86

2018

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Replication of human noroviruses in stem cell-derived human enteroids

Science (American Association for the Advancement of Science), 2016-09, Vol.353 (6306), p.1387-1393

2016

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Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

Journal of virology, 2016-01, Vol.90 (1), p.43-56

2016

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Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1576, p.229

2019

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Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (38), p.23782-23793

2020

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A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (4), p.E570-E579

2017

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Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract

Experimental biology and medicine (Maywood, N.J.), 2014-09, Vol.239 (9), p.1124-1134

2014

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Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

Viruses, 2019-07, Vol.11 (7), p.638

2019

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Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation

The Journal of clinical investigation, 2023-11, Vol.133 (21), p.1-15

2023

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Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases

Cellular and molecular gastroenterology and hepatology, 2018-01, Vol.5 (3), p.241-251

2018

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Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation

Cell reports (Cambridge), 2018-01, Vol.22 (4), p.1003-1015

2018

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The gastrointestinal frontier: IgA and viruses

Frontiers in immunology, 2013-11, Vol.4, p.402-402

2013

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Organoids to Dissect Gastrointestinal Virus-Host Interactions: What Have We Learned?

Viruses, 2021-05, Vol.13 (6), p.999

2021

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Infant and adult human intestinal enteroids are morphologically and functionally distinct

mBio, 2024-08, Vol.15 (8), p.e0131624

2024

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Multiomic Investigations into Lung Health and Disease

Microorganisms (Basel), 2023-08, Vol.11 (8), p.2116

2023

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Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

Molecular metabolism (Germany), 2021-02, Vol.44, p.101129-101129, Article 101129

2021

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Rotavirus antigenemia in children is associated with viremia

PLoS medicine, 2007-04, Vol.4 (4), p.e121-e121

2007

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Organoid Models for Infectious Disease

Annual review of medicine, 2022-01, Vol.73 (1), p.167-182

2022

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The Next MacGyver: A Platform to Study Intestinal Organoids Using High-Throughput Computer-Driven Microinjection

Cellular and molecular gastroenterology and hepatology, 2018-01, Vol.6 (3), p.352-353

Blutt, Sarah E., PhD

2018

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Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (45), p.1-11

2021

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Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

The Journal of biological chemistry, 2016-02, Vol.291 (8), p.3759-3766

2016

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Lymphotoxin Alpha-Deficient Mice Clear Persistent Rotavirus Infection after Local Generation of Mucosal IgA

Journal of Virology, 2013-01, Vol.87 (1), p.524-530

2013

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Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

iScience, 2020-10, Vol.23 (10), p.101618, Article 101618

2020

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Gut Bacterial Bouncers: Keeping Viral Pathogens out of the Epithelium

Cell host & microbe, 2019-11, Vol.26 (5), p.569-570

2019

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Use of organoids to study regenerative responses to intestinal damage

American journal of physiology: Gastrointestinal and liver physiology, 2019-12, Vol.317 (6), p.G845-G852

2019

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Human organoid cultures: transformative new tools for human virus studies

Replication of human noroviruses in stem cell-derived human enteroids

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections

Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids

A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection

Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract

Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation

Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases

Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation

The gastrointestinal frontier: IgA and viruses

Organoids to Dissect Gastrointestinal Virus-Host Interactions: What Have We Learned?

Infant and adult human intestinal enteroids are morphologically and functionally distinct

Multiomic Investigations into Lung Health and Disease

Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

Rotavirus antigenemia in children is associated with viremia

Organoid Models for Infectious Disease

The Next MacGyver: A Platform to Study Intestinal Organoids Using High-Throughput Computer-Driven Microinjection

Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection

Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

Lymphotoxin Alpha-Deficient Mice Clear Persistent Rotavirus Infection after Local Generation of Mucosal IgA

Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

Gut Bacterial Bouncers: Keeping Viral Pathogens out of the Epithelium

Use of organoids to study regenerative responses to intestinal damage

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