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CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations

Nature communications, 2019-03, Vol.10 (1), p.1136-14, Article 1136

2019

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Glyphosate and Aminomethylphosphonic Acid Content in Glyphosate-Resistant Soybean Leaves, Stems, and Roots and Associated Phytotoxicity Following a Single Glyphosate-Based Herbicide Application

Journal of agricultural and food chemistry, 2019-06, Vol.67 (22), p.6133-6142

2019

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Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide: The adaptive response

Free radical biology & medicine, 2016-04, Vol.93, p.155-164

2016

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Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

International journal of cancer, 2011-06, Vol.128 (11), p.2591-2601

2011

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Generation of induced pluripotent stem cells-derived hepatocyte-like cells for ex vivo gene therapy of primary hyperoxaluria type 1

Stem cell research, 2019-07, Vol.38, p.101467-101467, Article 101467

2019

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Severe Perinatal Presentations of Günther's Disease: Series of 20 Cases and Perspectives

Life (Basel, Switzerland), 2024-01, Vol.14 (1), p.130

2024

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Preventing hyperhomocysteinemia using vitamin B6 supplementation in Givosiran-treated acute intermittent porphyria: Highlights from a case report and brief literature review

Molecular genetics and metabolism reports, 2024-06, Vol.39, p.101076, Article 101076

2024

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An Orthotopic Model of Glioblastoma Is Resistant to Radiodynamic Therapy with 5-AminoLevulinic Acid

Cancers, 2022-08, Vol.14 (17), p.4244

2022

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Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (45), p.18238-18243

2013

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Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (3), p.917-922

2014

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Identification of novel UROS mutations in a patient with congenital erythropoietic porphyria and efficient treatment by phlebotomy

Molecular genetics and metabolism reports, 2021-06, Vol.27, p.100722, Article 100722

2021

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Lactose malabsorption and colonic fermentations alter host metabolism in rats

British journal of nutrition, 2013-08, Vol.110 (4), p.625-631

2013

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The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor

ACS medicinal chemistry letters, 2010-07, Vol.1 (4), p.170-174

2010

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High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: the increased luminal bulk connection

American journal of physiology: Gastrointestinal and liver physiology, 2014-08, Vol.307 (4), p.G459-G470

2014

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Targeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology

Biochemical and biophysical research communications, 2019-10, Vol.517 (4), p.677-683

2019

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Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria

Blood, 2020-11, Vol.136 (21), p.2457-2468

2020

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Missense UROS mutations causing congenital erythropoietic porphyria reduce UROS homeostasis that can be rescued by proteasome inhibition

Human molecular genetics, 2017-04, Vol.26 (8), p.1565-1576

2017

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A New Method for the Preparation of Aryl Vinyl Ethers

Journal of organic chemistry, 2001-12, Vol.66 (26), p.9043-9045

2001

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Spawning Habitat Unsuitability: An Impediment to Cisco Rehabilitation in Lake Michigan?

North American journal of fisheries management, 2011-10, Vol.31 (5), p.905-913

2011

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Genetic background influences hepcidin response to iron imbalance in a mouse model of hemolytic anemia (Congenital erythropoietic porphyria)

Biochemical and biophysical research communications, 2019-12, Vol.520 (2), p.297-303

2019

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High-protein diet differently modifies intestinal goblet cell characteristics and mucosal cytokine expression in ileum and colon

The Journal of nutritional biochemistry, 2015-01, Vol.26 (1), p.91-98

2015

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Late diagnosis of primary hyperoxaluria type III

Annals of clinical biochemistry, 2017-05, Vol.54 (3), p.406-411

2017

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Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells

Stem cell reports, 2020-09, Vol.15 (3), p.677-693

2020

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Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (16), p.2149-2152

2002

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Down-regulation of the phosphoenolpyruvate carboxykinase gene in human colon tumors and induction by omega-3 fatty acids

Biochimie, 2010-12, Vol.92 (12), p.1772-1777

2010

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CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations

Glyphosate and Aminomethylphosphonic Acid Content in Glyphosate-Resistant Soybean Leaves, Stems, and Roots and Associated Phytotoxicity Following a Single Glyphosate-Based Herbicide Application

Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide: The adaptive response

Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

Generation of induced pluripotent stem cells-derived hepatocyte-like cells for ex vivo gene therapy of primary hyperoxaluria type 1

Severe Perinatal Presentations of Günther's Disease: Series of 20 Cases and Perspectives

Preventing hyperhomocysteinemia using vitamin B6 supplementation in Givosiran-treated acute intermittent porphyria: Highlights from a case report and brief literature review

An Orthotopic Model of Glioblastoma Is Resistant to Radiodynamic Therapy with 5-AminoLevulinic Acid

Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria

Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses

Identification of novel UROS mutations in a patient with congenital erythropoietic porphyria and efficient treatment by phlebotomy

Lactose malabsorption and colonic fermentations alter host metabolism in rats

The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor

High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: the increased luminal bulk connection

Targeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology

Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria

Missense UROS mutations causing congenital erythropoietic porphyria reduce UROS homeostasis that can be rescued by proteasome inhibition

A New Method for the Preparation of Aryl Vinyl Ethers

Spawning Habitat Unsuitability: An Impediment to Cisco Rehabilitation in Lake Michigan?

Genetic background influences hepcidin response to iron imbalance in a mouse model of hemolytic anemia (Congenital erythropoietic porphyria)

High-protein diet differently modifies intestinal goblet cell characteristics and mucosal cytokine expression in ileum and colon

Late diagnosis of primary hyperoxaluria type III

Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells

Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding

Down-regulation of the phosphoenolpyruvate carboxykinase gene in human colon tumors and induction by omega-3 fatty acids

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