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HSV-1 LAT Promoter Deletion Viruses Exhibit Strain-Specific and LAT-Dependent Epigenetic Regulation of Latent Viral Genomes in Human Neurons

Journal of virology, 2023-02, Vol.97 (2), p.e0193522-e0193522

2023

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Signaling Pathway Reporter Screen with SARS-CoV-2 Proteins Identifies nsp5 as a Repressor of p53 Activity

Viruses, 2022-05, Vol.14 (5), p.1039

2022

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Mutational Inactivation of Herpes Simplex Virus 1 MicroRNAs Identifies Viral mRNA Targets and Reveals Phenotypic Effects in Culture

Journal of Virology, 2013-06, Vol.87 (12), p.6589-6603

2013

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The Polycomb Group Protein Bmi1 Binds to the Herpes Simplex Virus 1 Latent Genome and Maintains Repressive Histone Marks during Latency

Journal of Virology, 2009-08, Vol.83 (16), p.8173-8181

2009

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Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2

Scientific reports, 2023-01, Vol.13 (1), p.1639-1639, Article 1639

2023

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Very Broadly Effective Hemagglutinin-Directed Influenza Vaccines with Anti-Herpetic Activity

Vaccines (Basel), 2024-05, Vol.12 (5), p.537

2024

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Cervical prephrenic interneurons in the normal and lesioned spinal cord of the adult rat

Journal of comparative neurology (1911), 2008-12, Vol.511 (5), p.692-709

2008

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Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo

Viruses, 2022-04, Vol.14 (5), p.909

2022

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A Genomic Approach to Unravel Host-Pathogen Interaction in Chelonians: The Example of Testudinid Herpesvirus 3

PloS one, 2015-08, Vol.10 (8), p.e0134897-e0134897

2015

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Reactivation of Latent Epstein-Barr Virus: A Comparison after Exposure to Gamma, Proton, Carbon, and Iron Radiation

International journal of molecular sciences, 2018-09, Vol.19 (10), p.2961

2018

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Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines

Vaccines (Basel), 2020-05, Vol.8 (2), p.230

2020

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Regulated protein expression for in vivo gene therapy for neurological disorders: Progress, strategies, and issues

Neurobiology of disease, 2012-11, Vol.48 (2), p.212-221

2012

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Lund Human Mesencephalic (LUHMES) Neuronal Cell Line Supports Herpes Simplex Virus 1 Latency In Vitro

Journal of virology, 2019-03, Vol.93 (6)

2019

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A 77 Amino Acid Region in the N-Terminal Half of the HSV-1 E3 Ubiquitin Ligase ICP0 Contributes to Counteracting an Established Type 1 Interferon Response

Microbiology spectrum, 2022-08, Vol.10 (4), p.e0059322-e0059322

2022

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HSV1 latent transcription and non-coding RNA: A critical retrospective

Journal of neuroimmunology, 2017-07, Vol.308, p.65-101

2017

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A Chromatin Insulator-Like Element in the Herpes Simplex Virus Type 1 Latency-Associated Transcript Region Binds CCCTC-Binding Factor and Displays Enhancer-Blocking and Silencing Activities

Journal of Virology, 2006-03, Vol.80 (5), p.2358-2368

2006

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Specific Histone Tail Modification and Not DNA Methylation Is a Determinant of Herpes Simplex Virus Type 1 Latent Gene Expression

Journal of Virology, 2004-02, Vol.78 (3), p.1139-1149

2004

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Alphaherpesvirus Latency: A Dynamic State of Transcription and Reactivation

Advances in virus research, 2016, Vol.94, p.53-80

Bloom, David C

2016

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The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids

Cells (Basel, Switzerland), 2022-11, Vol.11 (22), p.3539

2022

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A viral lncRNA tethers HSV-1 genomes at the nuclear periphery to establish viral latency

Journal of virology, 2023-12, Vol.97 (12), p.e0143823-e0143823

2023

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Reliable Detection of Herpes Simplex Virus Sequence Variation by High-Throughput Resequencing

Viruses, 2017-08, Vol.9 (8), p.226

2017

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The Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer/rcr Is Hyperacetylated during Latency Independently of LAT Transcription

Journal of Virology, 2004-11, Vol.78 (22), p.12508-12518

2004

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The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication

Journal of virology, 2018-03, Vol.92 (6)

2018

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In Vivo Changes in the Patterns of Chromatin Structure Associated with the Latent Herpes Simplex Virus Type 1 Genome in Mouse Trigeminal Ganglia Can Be Detected at Early Times after Butyrate Treatment

Journal of Virology, 2007-12, Vol.81 (23), p.13248-13253

2007

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Herpes Simplex Virus 1 Strains 17syn + and KOS(M) Differ Greatly in Their Ability To Reactivate from Human Neurons In Vitro

Journal of virology, 2020-08, Vol.94 (15)

2020

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HSV-1 LAT Promoter Deletion Viruses Exhibit Strain-Specific and LAT-Dependent Epigenetic Regulation of Latent Viral Genomes in Human Neurons

Signaling Pathway Reporter Screen with SARS-CoV-2 Proteins Identifies nsp5 as a Repressor of p53 Activity

Mutational Inactivation of Herpes Simplex Virus 1 MicroRNAs Identifies Viral mRNA Targets and Reveals Phenotypic Effects in Culture

The Polycomb Group Protein Bmi1 Binds to the Herpes Simplex Virus 1 Latent Genome and Maintains Repressive Histone Marks during Latency

Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2

Very Broadly Effective Hemagglutinin-Directed Influenza Vaccines with Anti-Herpetic Activity

Cervical prephrenic interneurons in the normal and lesioned spinal cord of the adult rat

Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo

A Genomic Approach to Unravel Host-Pathogen Interaction in Chelonians: The Example of Testudinid Herpesvirus 3

Reactivation of Latent Epstein-Barr Virus: A Comparison after Exposure to Gamma, Proton, Carbon, and Iron Radiation

Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines

Regulated protein expression for in vivo gene therapy for neurological disorders: Progress, strategies, and issues

Lund Human Mesencephalic (LUHMES) Neuronal Cell Line Supports Herpes Simplex Virus 1 Latency In Vitro

A 77 Amino Acid Region in the N-Terminal Half of the HSV-1 E3 Ubiquitin Ligase ICP0 Contributes to Counteracting an Established Type 1 Interferon Response

HSV1 latent transcription and non-coding RNA: A critical retrospective

A Chromatin Insulator-Like Element in the Herpes Simplex Virus Type 1 Latency-Associated Transcript Region Binds CCCTC-Binding Factor and Displays Enhancer-Blocking and Silencing Activities

Specific Histone Tail Modification and Not DNA Methylation Is a Determinant of Herpes Simplex Virus Type 1 Latent Gene Expression

Alphaherpesvirus Latency: A Dynamic State of Transcription and Reactivation

The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids

A viral lncRNA tethers HSV-1 genomes at the nuclear periphery to establish viral latency

Reliable Detection of Herpes Simplex Virus Sequence Variation by High-Throughput Resequencing

The Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer/rcr Is Hyperacetylated during Latency Independently of LAT Transcription

The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication

In Vivo Changes in the Patterns of Chromatin Structure Associated with the Latent Herpes Simplex Virus Type 1 Genome in Mouse Trigeminal Ganglia Can Be Detected at Early Times after Butyrate Treatment

Herpes Simplex Virus 1 Strains 17syn + and KOS(M) Differ Greatly in Their Ability To Reactivate from Human Neurons In Vitro

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