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Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibiotics

Combinatorial chemistry & high throughput screening, 2005-05, Vol.8 (3), p.241

2005

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Mixture-Based Synthetic Combinatorial Libraries

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3743-3778

1999

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"Libraries from Libraries": Chemical Transformation of Combinatorial Libraries to Extend the Range and Repertoire of Chemical Diversity

Proceedings of the National Academy of Sciences - PNAS, 1994-11, Vol.91 (23), p.11138-11142

1994

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Design of model amphipathic peptides having potent antimicrobial activities

Biochemistry (Easton), 1992-12, Vol.31 (50), p.12688-12694

1992

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Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

Nature (London), 1991-11, Vol.354 (6348), p.84-86

1991

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Novel antimicrobial compounds identified using synthetic combinatorial library technology

Trends in biotechnology (Regular ed.), 1996-02, Vol.14 (2), p.60-65

1996

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Identification of antimicrobial peptides by using combinatorial libraries made up of unnatural amino acids

Antimicrobial Agents and Chemotherapy, 1994-10, Vol.38 (10), p.2280-2286

1994

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Hemolytic and antimicrobial activities of the twenty-four individual omission analogs of melittin

Biochemistry (Easton), 1991-05, Vol.30 (19), p.4671-4678

1991

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Synthetic combinatorial libraries : Novel discovery strategy for identification of antimicrobial agents

Antimicrobial agents and chemotherapy, 1996-05, Vol.40 (5), p.1067-1071

1996

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Lipid-induced conformation and lipid-binding properties of cytolytic and antimicrobial peptides: determination and biological specificity

BBA - Biomembranes, 1999-12, Vol.1462 (1), p.89-108

1999

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The use of synthetic peptide combinatorial libraries for the identification of bioactive peptides

BioTechniques, 1992-09, Vol.13 (3), p.412

1992

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Induced conformational states of amphipathic peptides in aqueous/lipid environments

Biophysical journal, 1995, Vol.68 (1), p.351-359

1995

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Combinatorial libraries: A tool to design antimicrobial and antifungal peptide analogues having lytic specificities for structure-activity relationship studies

Biopolymers, 2000, Vol.55 (1), p.74-87

2000

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Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death

Nature biotechnology, 1998-03, Vol.16 (3), p.286-291

1998

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Inhibition of a plant virus infection by analogs of melittin

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (26), p.12466-12469

1995

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Polyalanine-Based Peptides as Models for Self-Associated β-Pleated-Sheet Complexes

Biochemistry (Easton), 1997-07, Vol.36 (27), p.8393-8400

1997

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Determination of the secondary structure of selected melittin analogues with different haemolytic activities

Biochemical journal, 1994-04, Vol.299 (2), p.587-591

1994

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Perturbation of peptide conformations induced in anisotropic environments

Biopolymers, 1992-06, Vol.32 (6), p.575-583

1992

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Soluble combinatorial libraries of organic, peptidomimetic and peptide diversities

TrAC, Trends in analytical chemistry (Regular ed.), 1995-02, Vol.14 (2), p.83-92

1995

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Peptide binding domains determined through chemical modification of the side-chain functional groups

Biophysical journal, 1995-08, Vol.69 (2), p.604-611

1995

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The antimicrobial activity of hexapeptides derived from synthetic combinatorial libraries

Journal of Applied Bacteriology, 1995-01, Vol.78 (1), p.39-46

1995

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Evaluation of peptidepeptide interactions using reversed-phase high-performance liquid chromatography

Journal of Chromatography A, 1992-11, Vol.625 (2), p.199-206

1992

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Influence of tryptophan residues on melittin's hemolytic activity

Biochimica et biophysica acta, 1993-10, Vol.1202 (2), p.331-336

1993

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An N-Methyl-D-Aspartate Receptor Channel Blocker with Neuroprotective Activity

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (6), p.3519-3524

2001

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The Role of Amphipathicity in the Folding, Self-association and Biological Activity of Multiple Subunit Small Proteins (∗)

The Journal of biological chemistry, 1995-01, Vol.270 (3), p.1048-1056

1995

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Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibiotics

Mixture-Based Synthetic Combinatorial Libraries

"Libraries from Libraries": Chemical Transformation of Combinatorial Libraries to Extend the Range and Repertoire of Chemical Diversity

Design of model amphipathic peptides having potent antimicrobial activities

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

Novel antimicrobial compounds identified using synthetic combinatorial library technology

Identification of antimicrobial peptides by using combinatorial libraries made up of unnatural amino acids

Hemolytic and antimicrobial activities of the twenty-four individual omission analogs of melittin

Synthetic combinatorial libraries : Novel discovery strategy for identification of antimicrobial agents

Lipid-induced conformation and lipid-binding properties of cytolytic and antimicrobial peptides: determination and biological specificity

The use of synthetic peptide combinatorial libraries for the identification of bioactive peptides

Induced conformational states of amphipathic peptides in aqueous/lipid environments

Combinatorial libraries: A tool to design antimicrobial and antifungal peptide analogues having lytic specificities for structure-activity relationship studies

Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death

Inhibition of a plant virus infection by analogs of melittin

Polyalanine-Based Peptides as Models for Self-Associated β-Pleated-Sheet Complexes

Determination of the secondary structure of selected melittin analogues with different haemolytic activities

Perturbation of peptide conformations induced in anisotropic environments

Soluble combinatorial libraries of organic, peptidomimetic and peptide diversities

Peptide binding domains determined through chemical modification of the side-chain functional groups

The antimicrobial activity of hexapeptides derived from synthetic combinatorial libraries

Evaluation of peptidepeptide interactions using reversed-phase high-performance liquid chromatography

Influence of tryptophan residues on melittin's hemolytic activity

An N-Methyl-D-Aspartate Receptor Channel Blocker with Neuroprotective Activity

The Role of Amphipathicity in the Folding, Self-association and Biological Activity of Multiple Subunit Small Proteins (∗)

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