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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations

Nature communications, 2019-06, Vol.10 (1), p.2385-2385, Article 2385

2019

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Novel causative variants of VEXAS in UBA1 detected through whole genome transcriptome sequencing in a large cohort of hematological malignancies

Leukemia, 2023-05, Vol.37 (5), p.1080-1091

2023

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Bortezomib in the treatment of refractory thrombotic thrombocytopenic purpura

British journal of haematology, 2016-06, Vol.173 (5), p.779-785

2016

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Utility of Measurable Residual Disease (MRD) Assessment in Mantle Cell Lymphoma

Current treatment options in oncology, 2023-08, Vol.24 (8), p.929-947

2023

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JAFFAL: detecting fusion genes with long-read transcriptome sequencing

Genome Biology, 2022-01, Vol.23 (1), p.10-10, Article 10

2022

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Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL

Blood, 2022-02, Vol.139 (8), p.1198-1207

2022

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Variant acute promyelocytic leukaemia with novel NAB2::RARA fusion shows clinical all‐trans retinoic acid and arsenic trioxide sensitivity

British journal of haematology, 2023-08, Vol.202 (4), p.893-896

2023

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Mechanisms of intrinsic and acquired resistance to venetoclax in B-cell lymphoproliferative disease

Leukemia & lymphoma, 2020-01, Vol.61 (2), p.257-262

Blombery, Piers

2020

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Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphoma

Oncotarget, 2018-11, Vol.9 (90), p.36126-36136

2018

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T cell receptor beta locus sequencing early post-allogeneic stem cell transplant identifies patients at risk of initial and recurrent cytomegalovirus infection

Bone marrow transplantation (Basingstoke), 2021-10, Vol.56 (10), p.2582-2590

2021

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Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes

Blood, 2017-03, Vol.129 (12), p.1685-1690

2017

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Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia

Nature communications, 2017-03, Vol.8 (1), p.14756-14756, Article 14756

2017

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T-cell replete allogeneic stem cell transplant for mantle cell lymphoma achieves durable disease control, including against TP53-mutated disease

Bone marrow transplantation (Basingstoke), 2021-11, Vol.56 (11), p.2857-2859

2021

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The molecular pathogenesis of B-cell non-Hodgkin lymphoma

European journal of haematology, 2015-10, Vol.95 (4), p.280-293

2015

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Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

Haematologica (Roma), 2012-05, Vol.97 (5), p.780-783

2012

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CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing

Scientific reports, 2019-04, Vol.9 (1), p.6426-6426, Article 6426

2019

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Transient, flexible gene editing in zebrafish neutrophils and macrophages for determination of cell-autonomous functions

Disease models & mechanisms, 2021-07, Vol.14 (7)

2021

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Recovery of natural killer cell cytotoxicity in a p.A91V perforin homozygous patient following severe haemophagocytic lymphohistiocytosis

British journal of haematology, 2020-08, Vol.190 (3), p.458-461

2020

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Recovery of natural killer cell cytotoxicity in a A91V perforinhomozygous patient following severe haemophagocytic lymphohistiocytosis

British journal of haematology, 2020-08, Vol.190 (3), p.458-461

2020

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Detection of clinically relevant early genomic lesions in B‐cell malignancies from circulating tumour DNA using a single hybridisation‐based next generation sequencing assay

British journal of haematology, 2018-10, Vol.183 (1), p.146-149

2018

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High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot

Journal for immunotherapy of cancer, 2020-06, Vol.8 (1), p.e000792

2020

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Erdheim-Chester disease harboring the BRAF V600E mutation

Journal of clinical oncology, 2012-11, Vol.30 (32), p.e331-e332

2012

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Findings from precision oncology in the clinic: rare, novel variants are a significant contributor to scaling molecular diagnostics

BMC medical genomics, 2022-03, Vol.15 (1), p.70-70, Article 70

2022

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Natural killer receptor ligand expression on acute myeloid leukemia impacts survival and relapse after chemotherapy

Blood advances, 2018-02, Vol.2 (4), p.335-346

2018

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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations

Novel causative variants of VEXAS in UBA1 detected through whole genome transcriptome sequencing in a large cohort of hematological malignancies

Bortezomib in the treatment of refractory thrombotic thrombocytopenic purpura

Utility of Measurable Residual Disease (MRD) Assessment in Mantle Cell Lymphoma

JAFFAL: detecting fusion genes with long-read transcriptome sequencing

Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL

Variant acute promyelocytic leukaemia with novel NAB2::RARA fusion shows clinical all‐trans retinoic acid and arsenic trioxide sensitivity

Mechanisms of intrinsic and acquired resistance to venetoclax in B-cell lymphoproliferative disease

Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphoma

T cell receptor beta locus sequencing early post-allogeneic stem cell transplant identifies patients at risk of initial and recurrent cytomegalovirus infection

Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia

T-cell replete allogeneic stem cell transplant for mantle cell lymphoma achieves durable disease control, including against TP53-mutated disease

The molecular pathogenesis of B-cell non-Hodgkin lymphoma

Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing

Transient, flexible gene editing in zebrafish neutrophils and macrophages for determination of cell-autonomous functions

Recovery of natural killer cell cytotoxicity in a p.A91V perforin homozygous patient following severe haemophagocytic lymphohistiocytosis

Recovery of natural killer cell cytotoxicity in a A91V perforinhomozygous patient following severe haemophagocytic lymphohistiocytosis

Detection of clinically relevant early genomic lesions in B‐cell malignancies from circulating tumour DNA using a single hybridisation‐based next generation sequencing assay

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot

Efficacy and safety of avatrombopag in combination with immunosuppressive therapy in treatment-naïve and relapsed/refractory severe aplastic anaemia: protocol for the DIAAMOND-Ava-FIRST and DIAAMOND-Ava-NEXT Bayesian Optimal Phase II trials

Erdheim-Chester disease harboring the BRAF V600E mutation

Findings from precision oncology in the clinic: rare, novel variants are a significant contributor to scaling molecular diagnostics

Natural killer receptor ligand expression on acute myeloid leukemia impacts survival and relapse after chemotherapy

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