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Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism

Frontiers in cardiovascular medicine, 2018-12, Vol.5, p.187-187

2018

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Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

Circulation (New York, N.Y.), 2018-07, Vol.138 (4), p.377-393

2018

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2020 Jeffrey M. Hoeg Award Lecture: Calcifying Extracellular Vesicles as Building Blocks of Microcalcifications in Cardiovascular Disorders

Arteriosclerosis, thrombosis, and vascular biology, 2021-01, Vol.41 (1), p.117

2021

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Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy

European heart journal, 2022-02, Vol.43 (7), p.683-697

2022

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Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification

Frontiers in cardiovascular medicine, 2019-04, Vol.6, p.49-49

2019

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Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics

Nanomaterials (Basel, Switzerland), 2018-05, Vol.8 (5), p.296

2018

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Differential miRNA Loading Underpins Dual Harmful and Protective Roles for Extracellular Vesicles in Atherogenesis

Circulation research, 2019-02, Vol.124 (4), p.467-469

2019

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Animal Models of Calcific Aortic Valve Disease

International journal of inflammation, 2011-01, Vol.2011, p.364310-18

2011

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Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field

Circulation research, 2017-01, Vol.120 (2), p.270-273

2017

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Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis

Circulation research, 2021-04, Vol.128 (9), p.1371-1397

2021

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Network-Guided Multiomic Mapping of Aortic Valve Calcification

Arteriosclerosis, thrombosis, and vascular biology, 2023-03, Vol.43 (3), p.417

2023

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Challenges and Opportunities in Valvular Heart Disease: From Molecular Mechanisms to the Community

Arteriosclerosis, thrombosis, and vascular biology, 2024-04, Vol.44 (4), p.763

2024

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Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity

European heart journal, 2023-03, Vol.44 (10), p.885-898

2023

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18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images

Circulation. Cardiovascular imaging, 2019-01, Vol.12 (1), p.e007835-e007835

2019

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Morphological and Functional Evidence for the Contribution of the Pudendal Artery in Aging-Induced Erectile Dysfunction

Journal of sexual medicine, 2010-10, Vol.7 (10), p.3373-3384

2010

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Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis

Circulation (New York, N.Y.), 2023-08, Vol.148 (8), p.661-678

2023

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ApoC-III is a novel inducer of calcification in human aortic valves

The Journal of biological chemistry, 2021-01, Vol.296, p.100193-100193, Article 100193

2021

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Biomechanical conditioning of tissue engineered heart valves: Too much of a good thing?

Advanced drug delivery reviews, 2016-01, Vol.96, p.161-175

2016

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Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha-Mediated CD8 + T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease

Circulation (New York, N.Y.), 2022-02, Vol.145 (7), p.531-548

2022

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Directional Endothelial Communication by Polarized Extracellular Vesicle Release

Circulation research, 2024-02, Vol.134 (3), p.269

2024

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ApoA-I mimetics improve aortic stenosis-associated left-ventricular diastolic dysfunction but fail to benefit rabbit models with normal aortic valves

International journal of cardiology, 2021-06, Vol.332, p.159-161

2021

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Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling

Science advances, 2021-02, Vol.7 (6)

2021

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Deficiency of Natriuretic Peptide Receptor 2 Promotes Bicuspid Aortic Valves, Aortic Valve Disease, Left Ventricular Dysfunction, and Ascending Aortic Dilatations in Mice

Circulation research, 2018-02, Vol.122 (3), p.405-416

2018

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Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease

Circulation (New York, N.Y.), 2024-01, Vol.149 (5), p.391

2024

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Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis

Science advances, 2020-09, Vol.6 (38)

2020

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Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism

Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

2020 Jeffrey M. Hoeg Award Lecture: Calcifying Extracellular Vesicles as Building Blocks of Microcalcifications in Cardiovascular Disorders

Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy

Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification

Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics

Differential miRNA Loading Underpins Dual Harmful and Protective Roles for Extracellular Vesicles in Atherogenesis

Animal Models of Calcific Aortic Valve Disease

Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field

Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis

Network-Guided Multiomic Mapping of Aortic Valve Calcification

Challenges and Opportunities in Valvular Heart Disease: From Molecular Mechanisms to the Community

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity

18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images

Morphological and Functional Evidence for the Contribution of the Pudendal Artery in Aging-Induced Erectile Dysfunction

Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis

ApoC-III is a novel inducer of calcification in human aortic valves

Biomechanical conditioning of tissue engineered heart valves: Too much of a good thing?

Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha-Mediated CD8 + T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease

Directional Endothelial Communication by Polarized Extracellular Vesicle Release

ApoA-I mimetics improve aortic stenosis-associated left-ventricular diastolic dysfunction but fail to benefit rabbit models with normal aortic valves

Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling

Deficiency of Natriuretic Peptide Receptor 2 Promotes Bicuspid Aortic Valves, Aortic Valve Disease, Left Ventricular Dysfunction, and Ascending Aortic Dilatations in Mice

Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease

Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis

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