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Anthracycline-Related Cardiomyopathy After Childhood Cancer: Role of Polymorphisms in Carbonyl Reductase Genes—A Report From the Children's Oncology Group

Journal of clinical oncology, 2012-05, Vol.30 (13), p.1415-1421

2012

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Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group

Journal of clinical oncology, 2014-03, Vol.32 (7), p.647-653

2014

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Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline‐related congestive heart failure after childhood cancer

Cancer, 2008-06, Vol.112 (12), p.2789-2795

2008

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MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024

PloS one, 2012-11, Vol.7 (11), p.e48622-e48622

2012

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Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene

Toxicology letters, 2012-06, Vol.211 (3), p.266-273

2012

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Genotype Analysis of ABCC1 , NCF4 and CBR3 Polymorphism and the Association With Childhood Acute Lymphoblastic Leukemia in Mexican Childhood Population

Frontiers in pharmacology, 2021-02, Vol.11, p.616630

2021

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CBR3 V244M is associated with LVEF reduction in breast cancer patients treated with doxorubicin

Cardio-oncology (London, England), 2021-05, Vol.7 (1), p.17-10, Article 17

2021

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A Rapid, Reproducible, On-the-Fly Orthogonal Array Optimization Method for Targeted Protein Quantification by LC/MS and Its Application for Accurate and Sensitive Quantification of Carbonyl Reductases in Human Liver

Analytical chemistry (Washington), 2010-04, Vol.82 (7), p.2680-2689

2010

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Inhibition of Polymorphic Human Carbonyl Reductase 1 (CBR1) by the Cardioprotectant Flavonoid 7-monohydroxyethyl Rutoside (monoHER)

Pharmaceutical research, 2008-07, Vol.25 (7), p.1730-1734

2008

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Regulation of the Human Fc-Neonatal Receptor alpha-Chain Gene FCGRT by MicroRNA-3181

Pharmaceutical research, 2018-01, Vol.35 (1), p.15-9, Article 15

2018

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Analysis of Heteroplasmic Variants in the Cardiac Mitochondrial Genome of Individuals with Down Syndrome

Human mutation, 2017-01, Vol.38 (1), p.48-54

2017

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A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity

Drug metabolism and disposition, 2007-06, Vol.35 (6), p.973-980

2007

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Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors

Drug metabolism and disposition, 2009-02, Vol.37 (2), p.400-407

2009

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Cardiovascular diseases in survivors of childhood cancer

Cancer and metastasis reviews, 2020-03, Vol.39 (1), p.55-68

2020

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Comparative genome-wide DNA methylation analysis in myocardial tissue from donors with and without Down syndrome

Gene, 2021-01, Vol.764, p.145099-145099, Article 145099

2021

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Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment

Blood, 2003-05, Vol.101 (10), p.3862-3867

2003

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Insights into the transcriptional regulation of the anthracycline reductase AKR7A2 in human cardiomyocytes

Toxicology letters, 2019-06, Vol.307, p.11-16

2019

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Pharmacokinetics of Chemotherapeutic Drugs in Pediatric Patients With Down Syndrome and Leukemia

Journal of pediatric hematology/oncology, 2016-05, Vol.38 (4), p.283-287

2016

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Functional Characterization of the Promoter of Human Carbonyl Reductase 1 (CBR1). Role of XRE Elements in Mediating the Induction of CBR1 by Ligands of the Aryl Hydrocarbon Receptor

Molecular pharmacology, 2007-09, Vol.72 (3), p.734-743

2007

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Anthracycline-Related Cardiotoxicity in Patients with Acute Myeloid Leukemia and Down Syndrome: A Literature Review

Cardiovascular Toxicology, 2016-01, Vol.16 (1), p.5-13

2016

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Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3)

Drug metabolism and disposition, 2005-02, Vol.33 (2), p.254-257

2005

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Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM)

Biochimica et biophysica acta, 2015-07, Vol.1852 (7), p.1420-1427

2015

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CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children's Oncology Group Genome-Wide Association Study

Journal of clinical oncology, 2016-03, Vol.34 (8), p.863-870

2016

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Pharmacotherapeutic Considerations for Individuals with Down Syndrome

Pharmacotherapy, 2017-02, Vol.37 (2), p.214-220

2017

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Association of GSTM1 null variant with anthracycline‐related cardiomyopathy after childhood cancer—A Children's Oncology Group ALTE03N1 report

Cancer, 2020-09, Vol.126 (17), p.4051-4058

2020

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Anthracycline-Related Cardiomyopathy After Childhood Cancer: Role of Polymorphisms in Carbonyl Reductase Genes—A Report From the Children's Oncology Group

Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group

Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline‐related congestive heart failure after childhood cancer

MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024

Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene

Genotype Analysis of ABCC1 , NCF4 and CBR3 Polymorphism and the Association With Childhood Acute Lymphoblastic Leukemia in Mexican Childhood Population

CBR3 V244M is associated with LVEF reduction in breast cancer patients treated with doxorubicin

A Rapid, Reproducible, On-the-Fly Orthogonal Array Optimization Method for Targeted Protein Quantification by LC/MS and Its Application for Accurate and Sensitive Quantification of Carbonyl Reductases in Human Liver

Inhibition of Polymorphic Human Carbonyl Reductase 1 (CBR1) by the Cardioprotectant Flavonoid 7-monohydroxyethyl Rutoside (monoHER)

Regulation of the Human Fc-Neonatal Receptor alpha-Chain Gene FCGRT by MicroRNA-3181

Analysis of Heteroplasmic Variants in the Cardiac Mitochondrial Genome of Individuals with Down Syndrome

A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity

Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors

Cardiovascular diseases in survivors of childhood cancer

Comparative genome-wide DNA methylation analysis in myocardial tissue from donors with and without Down syndrome

Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment

Insights into the transcriptional regulation of the anthracycline reductase AKR7A2 in human cardiomyocytes

Pharmacokinetics of Chemotherapeutic Drugs in Pediatric Patients With Down Syndrome and Leukemia

Functional Characterization of the Promoter of Human Carbonyl Reductase 1 (CBR1). Role of XRE Elements in Mediating the Induction of CBR1 by Ligands of the Aryl Hydrocarbon Receptor

Anthracycline-Related Cardiotoxicity in Patients with Acute Myeloid Leukemia and Down Syndrome: A Literature Review

Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3)

Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM)

CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children's Oncology Group Genome-Wide Association Study

Pharmacotherapeutic Considerations for Individuals with Down Syndrome

Association of GSTM1 null variant with anthracycline‐related cardiomyopathy after childhood cancer—A Children's Oncology Group ALTE03N1 report

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