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Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections

Antimicrobial agents and chemotherapy, 2015-03, Vol.59 (3), p.1435-1440

2015

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Can patients be trained to expect shared decision making in clinical consultations? Feasibility study of a public library program to raise patient awareness

PloS one, 2018-12, Vol.13 (12), p.e0208449-e0208449

2018

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Antistaphylococcal Activity of TD-1792, a Multivalent Glycopeptide-Cephalosporin Antibiotic

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1584-1587

2012

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Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa: Novel Agents for Combination Therapy

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.105-116

2001

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The Aging, Community and Health Research Unit Community Partnership Program (ACHRU-CPP) for older adults with diabetes and multiple chronic conditions: study protocol for a randomized controlled trial

BMC geriatrics, 2022-02, Vol.22 (1), p.99-99, Article 99

2022

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Pharmacodynamics of TD-1792, a Novel Glycopeptide-Cephalosporin Heterodimer Antibiotic Used against Gram-Positive Bacteria, in a Neutropenic Murine Thigh Model

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1578-1583

2012

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Specificity of Induction of the vanA and vanB Operons in Vancomycin-Resistant Enterococci by Telavancin

Antimicrobial Agents and Chemotherapy, 2010-07, Vol.54 (7), p.2814-2818

2010

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Preparation of tetra-Boc-protected polymyxin B nonapeptide

Tetrahedron letters, 2007-03, Vol.48 (11), p.2003-2005

2007

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A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers

Antimicrobial agents and chemotherapy, 2019-07, Vol.63 (7)

2019

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In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor

Antimicrobial agents and chemotherapy, 2022-12, Vol.66 (12), p.e0092122-e0092122

2022

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Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228

Bioorganic & medicinal chemistry letters, 2018-02, Vol.28 (4), p.748-755

2018

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Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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RWJ-54428 (MC-02,479), a New Cephalosporin with High Affinity for Penicillin-Binding Proteins, Including PBP 2a, and Stability to Staphylococcal Beta-Lactamases

Antimicrobial Agents and Chemotherapy, 2003-02, Vol.47 (2), p.658-664

2003

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Impact of Inducible bla DHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne bla DHA-1 Expression

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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Impact of Inducible blaDHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne blaDHA-1 Expression

Antimicrobial agents and chemotherapy, 2018-09, Vol.62 (10)

2018

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Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.6329-6357

2021

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Playing cards on asthma management: a new interactive method for knowledge transfer to primary care physicians

Canadian respiratory journal, 2007, Vol.14 (8), p.480-484

2007

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In Vitro Activities of RWJ-54428 (MC-02,479) against Multiresistant Gram-Positive Bacteria

Antimicrobial Agents and Chemotherapy, 2001-05, Vol.45 (5), p.1422-1430

2001

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Strategies for involving patients and the public in scaling-up initiatives in health and social services: protocol for a scoping review and Delphi survey

Systematic reviews, 2021-02, Vol.10 (1), p.55-55, Article 55

2021

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IID572: A New Potentially Best-In-Class β‑Lactamase Inhibitor

ACS infectious diseases, 2019-07, Vol.5 (7), p.1045-1051

2019

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Opportunities and Challenges in Developing a Cryptosporidium Controlled Human Infection Model for Testing Antiparasitic Agents

ACS infectious diseases, 2021-05, Vol.7 (5), p.959-968

2021

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The patient-centered interview and the way it is taught. What do family physicians who have recently received their degree think?

Canadian family physician, 2002-11, Vol.48 (11), p.1800-1805

2002

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Activity of telavancin against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) in vitro and in an in vivo mouse model of bacteraemia

Journal of antimicrobial chemotherapy, 2010-04, Vol.65 (4), p.725-728

2010

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Primary health care professionals’ views on barriers and facilitators to the implementation of the Ottawa Decision Support Framework in practice

Patient education and counseling, 2006-11, Vol.63 (3), p.380-390

2006

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Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections

Can patients be trained to expect shared decision making in clinical consultations? Feasibility study of a public library program to raise patient awareness

Antistaphylococcal Activity of TD-1792, a Multivalent Glycopeptide-Cephalosporin Antibiotic

Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa: Novel Agents for Combination Therapy

The Aging, Community and Health Research Unit Community Partnership Program (ACHRU-CPP) for older adults with diabetes and multiple chronic conditions: study protocol for a randomized controlled trial

Pharmacodynamics of TD-1792, a Novel Glycopeptide-Cephalosporin Heterodimer Antibiotic Used against Gram-Positive Bacteria, in a Neutropenic Murine Thigh Model

Specificity of Induction of the vanA and vanB Operons in Vancomycin-Resistant Enterococci by Telavancin

Preparation of tetra-Boc-protected polymyxin B nonapeptide

A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers

In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae

In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae

RWJ-54428 (MC-02,479), a New Cephalosporin with High Affinity for Penicillin-Binding Proteins, Including PBP 2a, and Stability to Staphylococcal Beta-Lactamases

Impact of Inducible bla DHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne bla DHA-1 Expression

Impact of Inducible blaDHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne blaDHA-1 Expression

Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria

Playing cards on asthma management: a new interactive method for knowledge transfer to primary care physicians

In Vitro Activities of RWJ-54428 (MC-02,479) against Multiresistant Gram-Positive Bacteria

Strategies for involving patients and the public in scaling-up initiatives in health and social services: protocol for a scoping review and Delphi survey

IID572: A New Potentially Best-In-Class β‑Lactamase Inhibitor

Opportunities and Challenges in Developing a Cryptosporidium Controlled Human Infection Model for Testing Antiparasitic Agents

The patient-centered interview and the way it is taught. What do family physicians who have recently received their degree think?

Activity of telavancin against heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) in vitro and in an in vivo mouse model of bacteraemia

Primary health care professionals’ views on barriers and facilitators to the implementation of the Ottawa Decision Support Framework in practice

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