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Reflections on some pilot trials of gastrin receptor blockade in pancreatic cancer

European journal of cancer (1990), 2009-02, Vol.45 (3), p.360-364

Black, James W

2009

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Optimization of 1,3,4-Benzotriazepine-Based CCK2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion

Journal of medicinal chemistry, 2007-06, Vol.50 (13), p.3101-3112

2007

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Development of Peptide 3D Structure Mimetics: Rational Design of Novel Peptoid Cholecystokinin Receptor Antagonists

Journal of medicinal chemistry, 2000-09, Vol.43 (19), p.3505-3517

2000

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Effects of Acute and Chronic Administration of β-Adrenoceptor Ligands on Airway Function in a Murine Model of Asthma

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (14), p.4948-4953

2004

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Analysis of the effects of α1‐adrenoceptor antagonists on noradrenaline‐mediated contraction of rat small mesenteric artery

British journal of pharmacology, 1996-07, Vol.118 (5), p.1308-1316

1996

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Comparative analysis of the vagal stimulation of gastric acid secretion in rodent isolated stomach preparations

British journal of pharmacology, 1994-05, Vol.112 (1), p.93-96

1994

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Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium‐independent relaxation of rat isolated small mesenteric arteries

British journal of pharmacology, 1995-12, Vol.116 (8), p.3237-3242

1995

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Imidazoleacetic Acid-Ribotide: An Endogenous Ligand That Stimulates Imidazol(in)e Receptors

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (37), p.13677-13682

2004

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Inotropic 'A' ring substituted sulmazole and isomazole analogs

Journal of medicinal chemistry, 1990-08, Vol.33 (8), p.2231-2239

1990

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Gastrin Agonists and Antagonists

Pharmacology & toxicology, 2002-12, Vol.91 (6), p.275-281

2002

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Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK2) Antagonists

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.6803-6812

2005

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The interaction of choline esters, vagal stimulation and H2-receptor blockade on acid secretion in vitro

European journal of pharmacology, 1982-05, Vol.80 (2-3), p.217-224

1982

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Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion

Journal of medicinal chemistry, 2007-06, Vol.50 (13), p.3101-3112

2007

Volltextzugriff (PDF)

Optimization of 1,3,4-Benzotriazepine-Based CCK 2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion

Journal of medicinal chemistry, 2007-06, Vol.50 (13), p.3101-3112

2007

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Quantitative Analysis of the Formation and Diffusion of A1-Adenosine Receptor-Antagonist Complexes in Single Living Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (13), p.4673-4678

2004

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Use of a novel CCKB/gastrin receptor antagonist, gastrazole (JB5008) in patients with advanced pancreatic adenocarcinoma. Results of an open labeled pilot trial

Gastroenterology (New York, N.Y. 1943), 2001-04, Vol.120 (5), p.A612-A612

2001

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Analysis of the activity of α1‐adrenoceptor antagonists in rat aorta

British journal of pharmacology, 1996-05, Vol.118 (2), p.299-310

1996

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Stimulation of mucus output from rat colon in vivo

European journal of pharmacology, 1980-12, Vol.68 (4), p.417-425

1980

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TiPS on identity

Trends in pharmacological sciences (Regular ed.), 1996-04, Vol.17 (4), p.121-121

Black, James W.

1996

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Drugs from Emasculated Hormones: The Principle of Syntopic Antagonism (Nobel Lecture)

Angewandte Chemie (International ed.), 1989-07, Vol.28 (7), p.886-894

Black, James W.

1989

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Potential histamine H2-receptor antagonists. 2. N.alpha.-Guanylhistamine

Journal of medicinal chemistry, 1975-08, Vol.18 (8), p.830-833

1975

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Pharmacological analysis of the CCKB/gastrin receptors mediating pentagastrin‐stimulated gastric acid secretion in the isolated stomach of the immature rat

British journal of pharmacology, 1996-12, Vol.119 (7), p.1401-1410

1996

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Analysis of the action of idazoxan calls into question the reliability of the rat isolated small mesenteric artery assay as a predictor for α1-adrenoceptor-mediated pressor activity

Naunyn-Schmiedeberg's archives of pharmacology, 1996-08, Vol.354 (3), p.389-392

1996

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Pharmacological analysis of the CCK B /gastrin receptors mediating pentagastrin‐stimulated gastric acid secretion in the isolated stomach of the immature rat

British journal of pharmacology, 1996-12, Vol.119 (7), p.1401-1410

1996

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Application of a model to explore interspecies differences in acetylcholine M‐receptor‐stimulated gastric acid secretion

British journal of pharmacology, 1995-07, Vol.115 (6), p.961-968

1995

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Reflections on some pilot trials of gastrin receptor blockade in pancreatic cancer

Optimization of 1,3,4-Benzotriazepine-Based CCK2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion

Development of Peptide 3D Structure Mimetics: Rational Design of Novel Peptoid Cholecystokinin Receptor Antagonists

Effects of Acute and Chronic Administration of β-Adrenoceptor Ligands on Airway Function in a Murine Model of Asthma

Analysis of the effects of α1‐adrenoceptor antagonists on noradrenaline‐mediated contraction of rat small mesenteric artery

Comparative analysis of the vagal stimulation of gastric acid secretion in rodent isolated stomach preparations

Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium‐independent relaxation of rat isolated small mesenteric arteries

Imidazoleacetic Acid-Ribotide: An Endogenous Ligand That Stimulates Imidazol(in)e Receptors

Inotropic 'A' ring substituted sulmazole and isomazole analogs

Gastrin Agonists and Antagonists

Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK2) Antagonists

The interaction of choline esters, vagal stimulation and H2-receptor blockade on acid secretion in vitro

Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion

Optimization of 1,3,4-Benzotriazepine-Based CCK 2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion

Quantitative Analysis of the Formation and Diffusion of A1-Adenosine Receptor-Antagonist Complexes in Single Living Cells

Use of a novel CCKB/gastrin receptor antagonist, gastrazole (JB5008) in patients with advanced pancreatic adenocarcinoma. Results of an open labeled pilot trial

Analysis of the activity of α1‐adrenoceptor antagonists in rat aorta

Stimulation of mucus output from rat colon in vivo

TiPS on identity

Drugs from Emasculated Hormones: The Principle of Syntopic Antagonism (Nobel Lecture)

Potential histamine H2-receptor antagonists. 2. N.alpha.-Guanylhistamine

Pharmacological analysis of the CCKB/gastrin receptors mediating pentagastrin‐stimulated gastric acid secretion in the isolated stomach of the immature rat

Analysis of the action of idazoxan calls into question the reliability of the rat isolated small mesenteric artery assay as a predictor for α1-adrenoceptor-mediated pressor activity

Pharmacological analysis of the CCK B /gastrin receptors mediating pentagastrin‐stimulated gastric acid secretion in the isolated stomach of the immature rat

Application of a model to explore interspecies differences in acetylcholine M‐receptor‐stimulated gastric acid secretion

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