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Dose metric considerations in in vitro assays to improve quantitative in vitro – in vivo dose extrapolations

Toxicology (Amsterdam), 2015-06, Vol.332, p.30-40

2015

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Biokinetics in repeated-dosing in vitro drug toxicity studies

Toxicology in vitro, 2015-12, Vol.30 (1), p.217-224

2015

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Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Toxicology in vitro, 2013-06, Vol.27 (4), p.1320-1346

2013

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In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death

Toxicology in vitro, 2017-03, Vol.39, p.104-110

2017

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The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man

Toxicological sciences, 2010-12, Vol.118 (2), p.470-484

2010

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Biokinetic Modeling and in Vitro-in Vivo Extrapolations

Journal of toxicology and environmental health. Part B, Critical reviews, 2010-02, Vol.13 (2-4), p.242-252

Blaauboer, Bas J.

2010

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Evidence-based absorption, distribution, metabolism, excretion (ADME) and its interplay with alternative toxicity methods

ALTEX, alternatives to animal experimentation, 2016-01, Vol.33 (4), p.343-358

2016

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The long and winding road of progress in the use of in vitro data for risk assessment purposes: From “carnation test” to integrated testing strategies

Toxicology (Amsterdam), 2015-06, Vol.332, p.4-7

Blaauboer, Bas J

2015

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In vitro, ex vivo, in vivo toxicology, the terminology issue

Toxicology in vitro, 2017-12, Vol.45 (Pt 1), p.iii-iv

2017

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Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

Toxicology in vitro, 2015-12, Vol.30 (1), p.52-61

2015

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Quantitative in vitro to in vivo extrapolation (QIVIVE): An essential element for in vitro-based risk assessment

Toxicology (Amsterdam), 2015-06, Vol.332, p.1-3

2015

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Transport of Chlorpromazine in the Caco-2 Cell Permeability Assay: A Kinetic Study

Chemical research in toxicology, 2012-07, Vol.25 (7), p.1442-1451

2012

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Influence of in Vitro Assay Setup on the Apparent Cytotoxic Potency of Benzalkonium Chlorides

Chemical research in toxicology, 2019-06, Vol.32 (6), p.1103-1114

2019

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Considering new methodologies in strategies for safety assessment of foods and food ingredients

Food and chemical toxicology, 2016-05, Vol.91, p.19-35

2016

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Evaluation of simple in vitro to in vivo extrapolation approaches for environmental compounds

Toxicology in vitro, 2014-03, Vol.28 (2), p.164-170

2014

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A novel hypothesis for an alkaline phosphatase ‘rescue’ mechanism in the hepatic acute phase immune response

Biochimica et biophysica acta, 2013-12, Vol.1832 (12), p.2044-2056

2013

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Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling

Archives of toxicology, 2015-07, Vol.89 (7), p.1135-1148

2015

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A tribute to Daniel Acosta celebrating his 25 years as editor of Toxicology in Vitro

Toxicology in vitro, 2020-04, Vol.64, p.104637-104637, Article 104637

2020

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CON4EI: CONsortium for in vitro Eye Irritation testing strategy

Toxicology in vitro, 2018-06, Vol.49, p.1-1

2018

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The contribution of in vitro toxicity data in hazard and risk assessment: Current limitations and future perspectives

Toxicology letters, 2008-08, Vol.180 (2), p.81-84

Blaauboer, Bas J.

2008

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Quantifying Processes Determining the Free Concentration of Phenanthrene in Basal Cytotoxicity Assays

Chemical research in toxicology, 2012-02, Vol.25 (2), p.436-445

2012

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Excessive levels of diverse phytoestrogens can modulate steroidogenesis and cell migration of KGN human granulosa-derived tumor cells

Toxicology reports, 2014-01, Vol.1 (C), p.360-372

2014

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A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme

Toxicology in vitro, 2018-08, Vol.50, p.137-146

2018

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New Approach Methodologies for Human-Relevant Biokinetics Predictions: Meeting the Paradigm Shift in Toxicology Towards an Animal-Free Chemical Risk Assessment

ALTEX, alternatives to animal experimentation, 2020-01, Vol.37 (4), p.607

2020

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Dose metric considerations in in vitro assays to improve quantitative in vitro – in vivo dose extrapolations

Biokinetics in repeated-dosing in vitro drug toxicity studies

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress

In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death

The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man

Biokinetic Modeling and in Vitro-in Vivo Extrapolations

Evidence-based absorption, distribution, metabolism, excretion (ADME) and its interplay with alternative toxicity methods

The long and winding road of progress in the use of in vitro data for risk assessment purposes: From “carnation test” to integrated testing strategies

In vitro, ex vivo, in vivo toxicology, the terminology issue

Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

Quantitative in vitro to in vivo extrapolation (QIVIVE): An essential element for in vitro-based risk assessment

Transport of Chlorpromazine in the Caco-2 Cell Permeability Assay: A Kinetic Study

Influence of in Vitro Assay Setup on the Apparent Cytotoxic Potency of Benzalkonium Chlorides

Considering new methodologies in strategies for safety assessment of foods and food ingredients

Evaluation of simple in vitro to in vivo extrapolation approaches for environmental compounds

A novel hypothesis for an alkaline phosphatase ‘rescue’ mechanism in the hepatic acute phase immune response

Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling

A tribute to Daniel Acosta celebrating his 25 years as editor of Toxicology in Vitro

CON4EI: CONsortium for in vitro Eye Irritation testing strategy

The contribution of in vitro toxicity data in hazard and risk assessment: Current limitations and future perspectives

Quantifying Processes Determining the Free Concentration of Phenanthrene in Basal Cytotoxicity Assays

Excessive levels of diverse phytoestrogens can modulate steroidogenesis and cell migration of KGN human granulosa-derived tumor cells

A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme

New Approach Methodologies for Human-Relevant Biokinetics Predictions: Meeting the Paradigm Shift in Toxicology Towards an Animal-Free Chemical Risk Assessment

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