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In vitro neuroendocrine effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the AhR-expressing hypothalamic rat GnV-3 cell line

Toxicology (Amsterdam), 2013-09, Vol.311 (3), p.124-134

2013

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Integrated testing strategies making use of in vitro–in vivo extrapolations

Toxicology letters, 2011-08, Vol.205, p.S17-S17

Blaauboer, B.J.

2011

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Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Toxicology in vitro, 2013-06, Vol.27 (4), p.1320-1346

2013

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Hepatocyte function of human adult liver stem cells in 3D organoid culture

Toxicology letters, 2016-09, Vol.258, p.S140-S140

2016

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Methods of in vitro toxicology

Food and chemical toxicology, 2002-02, Vol.40 (2), p.193-236

2002

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An Integrated Approach to the Prediction of Systemic Toxicity using Computer-based Biokinetic Models and Biological In vitro Test Methods: Overview of a Prevalidation Study Based on the ECITTS Project

Toxicology in vitro, 1999-08, Vol.13 (4), p.549-554

1999

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Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologycally based kinetic modeling

Archives of toxicology, 2015, Vol.89 (7)

2015

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Biokinetics in vitro

Toxicology letters, 2011-08, Vol.205, p.S16-S16

2011

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The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers

Biochemical pharmacology, 1990-12, Vol.40 (11), p.2525-2534

1990

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The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary

Toxicology letters, 2003-02, Vol.138 (1), p.161-171

Blaauboer, B.J

2003

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Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice

Regulatory toxicology and pharmacology, 2011-10, Vol.61 (1), p.105-114

2011

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PII: S0887-2333(03)00227-3

Toxicology in vitro, 2004, Vol.18 (2), p.151-152

2004

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Toward relevant biomarkers in in vitro developmental toxicity and their extrapolation to the in vivo situation : Reviews

Expert opinion on drug metabolism & toxicology, 2012, Vol.8 (1)

2012

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An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing

Regulatory toxicology and pharmacology, 2005-08, Vol.42 (3), p.284-295

2005

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Decrease of intercellular pH as possible mechanism of action of embryotoxicity of glycol ether alkoxyacetic acid metabolites

Toxicology and applied pharmacology, 2010, Vol.245 (2)

2010

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The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-respomse curves for in vivo developmental toxicity of glycol ethers in rat and man

Toxicological sciences, 2010, Vol.118 (2)

2010

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Measuring and modeling bioavailability in in vitro systems

Chemico-biological interactions, 2007-08, Vol.169 (2), p.137-137

2007

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Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared to the in vivo potency of their parent compounds

Toxicological sciences, 2009, Vol.110 (1)

2009

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assessment of repeated dose toxicity in vitro: a proposed approach

Alternatives to laboratory animals, 2006, Vol.34 (3), p.315-341

2006

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Effects of the peroxisome proliferator mono(2-ethylhexyl)phthalate in primary hepatocyte cultures derived from rat, guinea pig, rabbit and monkey

Biochemical pharmacology, 1993-06, Vol.45 (12), p.2425-2434

1993

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Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures

Biochemical pharmacology, 1991-07, Vol.42 (2), p.381-390

1991

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Sulphadimidine metabolism in vitro. I. Sex differences in acetylation and hydroxylation in cultured rat hepatocytes

Journal of veterinary pharmacology and therapeutics, 1993-09, Vol.16 (3), p.343-349

1993

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Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures: The effects of model inducers on apoproteins and biotransformation activities

Biochemical pharmacology, 1991-07, Vol.42 (2), p.381-390

1991

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Structure elucidation of acid reaction products of indole-3-carbinol: Detection in vivo and enzyme induction in vitro

Chemico-biological interactions, 1991, Vol.80 (3), p.303-315

1991

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Evaluation of In Vitro-based simulations of toluene uptake and metabolism in rats

Toxicology in vitro, 1997-10, Vol.11 (5), p.485-489

1997

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In vitro neuroendocrine effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the AhR-expressing hypothalamic rat GnV-3 cell line

Integrated testing strategies making use of in vitro–in vivo extrapolations

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

Hepatocyte function of human adult liver stem cells in 3D organoid culture

Methods of in vitro toxicology

An Integrated Approach to the Prediction of Systemic Toxicity using Computer-based Biokinetic Models and Biological In vitro Test Methods: Overview of a Prevalidation Study Based on the ECITTS Project

Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologycally based kinetic modeling

Biokinetics in vitro

The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers

The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary

Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice

PII: S0887-2333(03)00227-3

Toward relevant biomarkers in in vitro developmental toxicity and their extrapolation to the in vivo situation : Reviews

An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing

Decrease of intercellular pH as possible mechanism of action of embryotoxicity of glycol ether alkoxyacetic acid metabolites

The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-respomse curves for in vivo developmental toxicity of glycol ethers in rat and man

Measuring and modeling bioavailability in in vitro systems

Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared to the in vivo potency of their parent compounds

assessment of repeated dose toxicity in vitro: a proposed approach

Effects of the peroxisome proliferator mono(2-ethylhexyl)phthalate in primary hepatocyte cultures derived from rat, guinea pig, rabbit and monkey

Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures

Sulphadimidine metabolism in vitro. I. Sex differences in acetylation and hydroxylation in cultured rat hepatocytes

Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures: The effects of model inducers on apoproteins and biotransformation activities

Structure elucidation of acid reaction products of indole-3-carbinol: Detection in vivo and enzyme induction in vitro

Evaluation of In Vitro-based simulations of toluene uptake and metabolism in rats

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