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Neutralizing the Neutralizers in AAV Gene Therapy

Molecular therapy, 2020-08, Vol.28 (8), p.1741-1742

2020

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Clinical development of gene therapy: results and lessons from recent successes

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16034-16034, Article 16034

2016

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Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A

Frontiers in immunology, 2017-11, Vol.8, p.1604-1604

2017

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Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4+CD25+FoxP3+ Treg

Blood, 2015-05, Vol.125 (19), p.2937-2947

2015

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Regulatory T cell therapy: Current and future design perspectives

Cellular immunology, 2020-10, Vol.356, p.104193-104193, Article 104193

2020

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B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin

Frontiers in immunology, 2020-06, Vol.11, p.1293-1293

2020

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Reprogrammed CD4 + T Cells That Express FoxP3 + Control Inhibitory Antibody Formation in Hemophilia A Mice

Frontiers in immunology, 2019-02, Vol.10, p.274-274

2019

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Gene Therapy With Regulatory T Cells: A Beneficial Alliance

Frontiers in immunology, 2018-03, Vol.9, p.554-554

2018

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Distinct functions and transcriptional signatures in orally induced regulatory T cell populations

Frontiers in immunology, 2023-10, Vol.14, p.1278184-1278184

2023

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Type I Interferon-Sensitive Recombinant Newcastle Disease Virus for Oncolytic Virotherapy

Journal of Virology, 2010-04, Vol.84 (8), p.3835-3844

2010

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Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer

Cellular immunology, 2019-08, Vol.342, p.103682-103682, Article 103682

2019

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CD8 T cells protect adult naive mice from JEV-induced morbidity via lytic function

PLoS neglected tropical diseases, 2017-02, Vol.11 (2), p.e0005329-e0005329

2017

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B cell focused transient immune suppression protocol for efficient AAV readministration to the liver

Molecular therapy. Methods & clinical development, 2024-03, Vol.32 (1), p.101216-101216, Article 101216

2024

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Incorporation of Host Complement Regulatory Proteins into Newcastle Disease Virus Enhances Complement Evasion

Journal of Virology, 2012-12, Vol.86 (23), p.12708-12716

2012

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Toll-like receptor responses to Peste des petits ruminants virus in goats and water buffalo

PloS one, 2014-11, Vol.9 (11), p.e111609-e111609

2014

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Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity

Molecular therapy. Methods & clinical development, 2020-12, Vol.19, p.347-361

2020

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Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

Molecular therapy. Methods & clinical development, 2014-07, Vol.1 (C), p.14030, Article 14030

2014

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Dynamics of antigen presentation to transgene product-specific CD4 + T cells and of Treg induction upon hepatic AAV gene transfer

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16083-16083, Article 16083

2016

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Role of FoxP3 + Regulatory T Cells in Modulating Immune Responses to Adeno-Associated Virus Gene Therapy

Human gene therapy, 2024-07, Vol.35 (13-14), p.439-450

2024

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Chopping down antibodies for a good cause

Molecular therapy, 2024-07, Vol.32 (7), p.2040-2041

2024

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Immune Modulatory Cell Therapy for Hemophilia B Based on CD20-Targeted Lentiviral Gene Transfer to Primary B Cells

Molecular therapy. Methods & clinical development, 2017-06, Vol.5 (C), p.76-82

2017

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Sweeten the deal: Glycopolymer-based engineering to modulate autoreactive T cell responses

Molecular therapy, 2023-11, Vol.31 (11), p.3119-3120

2023

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Reprogrammed CD4+ T Cells That Express FoxP3+ Effectively Control Inhibitory Antibody Development in Hemophilic Mice

Blood, 2017-12, Vol.130, p.175-175

2017

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Key Role of Kupffer Cells in IL-1 Dependent Activation of CD8+ T Cell Responses to AAV Transgene Product in Liver

Blood, 2022-11, Vol.140 (Supplement 1), p.4928-4929

2022

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Role of orally induced regulatory T cells in immunotherapy and tolerance

Cellular immunology, 2021-01, Vol.359, p.104251-104251, Article 104251

2021

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Neutralizing the Neutralizers in AAV Gene Therapy

Clinical development of gene therapy: results and lessons from recent successes

Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A

Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4+CD25+FoxP3+ Treg

Regulatory T cell therapy: Current and future design perspectives

B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin

Reprogrammed CD4 + T Cells That Express FoxP3 + Control Inhibitory Antibody Formation in Hemophilia A Mice

Gene Therapy With Regulatory T Cells: A Beneficial Alliance

Distinct functions and transcriptional signatures in orally induced regulatory T cell populations

Type I Interferon-Sensitive Recombinant Newcastle Disease Virus for Oncolytic Virotherapy

Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer

CD8 T cells protect adult naive mice from JEV-induced morbidity via lytic function

B cell focused transient immune suppression protocol for efficient AAV readministration to the liver

Incorporation of Host Complement Regulatory Proteins into Newcastle Disease Virus Enhances Complement Evasion

Toll-like receptor responses to Peste des petits ruminants virus in goats and water buffalo

Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity

Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

Dynamics of antigen presentation to transgene product-specific CD4 + T cells and of Treg induction upon hepatic AAV gene transfer

Role of FoxP3 + Regulatory T Cells in Modulating Immune Responses to Adeno-Associated Virus Gene Therapy

Chopping down antibodies for a good cause

Immune Modulatory Cell Therapy for Hemophilia B Based on CD20-Targeted Lentiviral Gene Transfer to Primary B Cells

Sweeten the deal: Glycopolymer-based engineering to modulate autoreactive T cell responses

Reprogrammed CD4+ T Cells That Express FoxP3+ Effectively Control Inhibitory Antibody Development in Hemophilic Mice

Key Role of Kupffer Cells in IL-1 Dependent Activation of CD8+ T Cell Responses to AAV Transgene Product in Liver

Role of orally induced regulatory T cells in immunotherapy and tolerance

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