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Rational Design of a Triple Helix-Specific Intercalating Ligand

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (7), p.3591-3596

1998

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Synthesis and evaluation of new 6-amino- substituted benzo[c]phenanthridine derivatives

Journal of medicinal chemistry, 1993-11, Vol.36 (23), p.3686-3692

1993

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In vitro cytotoxicity of s16020-2, a new olivacine derivative

Investigational new drugs, 1996-01, Vol.14 (2), p.169-180

1996

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Diphenyl quinolines and isoquinolines : Synthesis and primary biological evaluation

Bioorganic & medicinal chemistry, 2000-11, Vol.8 (11), p.2629-2641

2000

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Synthesis and Evaluation of 9-Hydroxy-5-methyl- (and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazole-1-N-[(dialkylamino)alkyl]carboxamides, a New Promising Series of Antitumor Olivacine Derivatives

Journal of medicinal chemistry, 1994-07, Vol.37 (15), p.2445-2452

1994

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Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation

Bioorganic & medicinal chemistry, 2000-11, Vol.8 (11), p.2629

2000

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4-Benzyl and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones: In Vitro Evaluation of New C-3-Amino-Substituted and C-5,6-Alkyl-Substituted Analogues against Clinically Important HIV Mutant Strains

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1948-1964

2005

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Triple-Helix Directed Cleavage of Double-Stranded DNA by Benzoquinoquinoxaline-1,10-phenanthroline Conjugates

Chembiochem : a European journal of chemical biology, 2004-11, Vol.5 (11), p.1550-1557

2004

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Synthesis and Biological Evaluation of 6-(9-Hydroxy-5-methyl (and 5, 6-Dimethyl)-6H-pyrido[4, 3-b]carbazol-1-yl)picolinic Amides as New Olivacine Derivatives

Chemical and Pharmaceutical Bulletin, 1996/11/15, Vol.44(11), pp.2169-2172

1996

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Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Bioorganic & medicinal chemistry, 1999-07, Vol.7 (7), p.1281-1293

1999

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Synthesis of 9-O-Substituted Derivatives of 9-Hydroxy-5,6-dimethyl-6H- pyrido[4,3-b]carbazole-1-carboxylic Acid (2-(Dimethylamino)ethyl)amide and Their 10- and 11-Methyl Analogues with Improved Antitumor Activity

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2191-2203

1999

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Synthesis of 13H-Benzo[6,7]- and 13H-Benzo[4,5]indolo[3,2-c]- quinolines: A New Series of Potent Specific Ligands for Triplex DNA

Journal of the American Chemical Society, 1998-03, Vol.120 (11), p.2501-2507

1998

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Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

Bioorganic & medicinal chemistry letters, 1998-04, Vol.8 (7), p.793-798

1998

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4-Benzyl- and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones, a New Family of Potent Anti-HIV Agents: Optimization and in Vitro Evaluation against Clinically Important HIV Mutant Strains

Journal of medicinal chemistry, 2004-10, Vol.47 (22), p.5501-5514

2004

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Synthesis of 11H-furo[3',2':7,8]benzopyrano[3,4-c]pyridin-11-one and 6,8-dimethyl-10H-pyrano[2',3':4,5]benzofuro[3,2-c]pyridin-10-one (pyridoangelicins)

Heterocycles, 1992, Vol.34 (7), p.1353-1364

1992

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Synthesis and Evaluation of “AZT-HEPT”, “AZT-Pyridinone”, and “ddC-HEPT” Conjugates as Inhibitors of HIV Reverse Transcriptase

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.1927-1939

2000

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A New Series of Pyridinone Derivatives as Potent Non-Nucleoside Human Immunodeficiency Virus Type 1 Specific Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4679-4686

1995

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Stable Triple-Helical DNA Complexes Formed by Benzopyridoindole− and Benzopyridoquinoxaline− Oligonucleotide Conjugates

Journal of the American Chemical Society, 1997-01, Vol.119 (2), p.263-268

1997

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Synthesis and Biological Properties of New Benz[h]isoquinoline Derivatives

Chemical and Pharmaceutical Bulletin, 1994/04/15, Vol.42(4), pp.892-895

1994

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Synthesis and Binding Properties of Oligo-2‘-deoxyribonucleotides Conjugated with Triple-Helix-Specific Intercalators: Benzo[e] and Benzo[g] Pyridoindoles

Bioconjugate chemistry, 2003, Vol.14 (1), p.120-135

2003

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Synthesis of psoralens and analogues

Journal of photochemistry and photobiology. B, Biology, 1992-06, Vol.14 (1), p.23-46

Bisagni, Emile

1992

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Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2000-10, Vol.43 (21), p.3949-3962

2000

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Optimization of Triple-Helix-Directed DNA Cleavage by Benzoquinoquinoxaline-Ethylenediaminetetraacetic Acid Conjugates

Chembiochem : a European journal of chemical biology, 2003-09, Vol.4 (9), p.856-862

2003

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Selective stabilization of DNA triple helices by benzopyridoindole derivatives

Journal of the American Chemical Society, 1995-10, Vol.117 (41), p.10212-10219

1995

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Synthesis, DNA Binding, and Cleaving Properties of an Ellipticine−Salen·Copper Conjugate

Bioconjugate chemistry, 1997-11, Vol.8 (6), p.789-792

1997

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Rational Design of a Triple Helix-Specific Intercalating Ligand

Synthesis and evaluation of new 6-amino- substituted benzo[c]phenanthridine derivatives

In vitro cytotoxicity of s16020-2, a new olivacine derivative

Diphenyl quinolines and isoquinolines : Synthesis and primary biological evaluation

Synthesis and Evaluation of 9-Hydroxy-5-methyl- (and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazole-1-N-[(dialkylamino)alkyl]carboxamides, a New Promising Series of Antitumor Olivacine Derivatives

Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation

4-Benzyl and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones: In Vitro Evaluation of New C-3-Amino-Substituted and C-5,6-Alkyl-Substituted Analogues against Clinically Important HIV Mutant Strains

Triple-Helix Directed Cleavage of Double-Stranded DNA by Benzoquinoquinoxaline-1,10-phenanthroline Conjugates

Synthesis and Biological Evaluation of 6-(9-Hydroxy-5-methyl (and 5, 6-Dimethyl)-6H-pyrido[4, 3-b]carbazol-1-yl)picolinic Amides as New Olivacine Derivatives

Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Synthesis of 9-O-Substituted Derivatives of 9-Hydroxy-5,6-dimethyl-6H- pyrido[4,3-b]carbazole-1-carboxylic Acid (2-(Dimethylamino)ethyl)amide and Their 10- and 11-Methyl Analogues with Improved Antitumor Activity

Synthesis of 13H-Benzo[6,7]- and 13H-Benzo[4,5]indolo[3,2-c]- quinolines: A New Series of Potent Specific Ligands for Triplex DNA

Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

4-Benzyl- and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones, a New Family of Potent Anti-HIV Agents: Optimization and in Vitro Evaluation against Clinically Important HIV Mutant Strains

Synthesis of 11H-furo[3',2':7,8]benzopyrano[3,4-c]pyridin-11-one and 6,8-dimethyl-10H-pyrano[2',3':4,5]benzofuro[3,2-c]pyridin-10-one (pyridoangelicins)

Synthesis and Evaluation of “AZT-HEPT”, “AZT-Pyridinone”, and “ddC-HEPT” Conjugates as Inhibitors of HIV Reverse Transcriptase

A New Series of Pyridinone Derivatives as Potent Non-Nucleoside Human Immunodeficiency Virus Type 1 Specific Reverse Transcriptase Inhibitors

Stable Triple-Helical DNA Complexes Formed by Benzopyridoindole− and Benzopyridoquinoxaline− Oligonucleotide Conjugates

Synthesis and Biological Properties of New Benz[h]isoquinoline Derivatives

Synthesis and Binding Properties of Oligo-2‘-deoxyribonucleotides Conjugated with Triple-Helix-Specific Intercalators: Benzo[e] and Benzo[g] Pyridoindoles

Synthesis of psoralens and analogues

Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

Optimization of Triple-Helix-Directed DNA Cleavage by Benzoquinoquinoxaline-Ethylenediaminetetraacetic Acid Conjugates

Selective stabilization of DNA triple helices by benzopyridoindole derivatives

Synthesis, DNA Binding, and Cleaving Properties of an Ellipticine−Salen·Copper Conjugate

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