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P0645 : Non-synonymous single-nucleotide polymorphisms (SNPs) in TLR7 do not impact GS-9620 dependent TLR7 activation

Journal of hepatology, 2015-04, Vol.62, p.S561-S561

2015

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Antiviral activity of GS-5801, a liver-targeted prodrug of a lysine demethylase 5 inhibitor, in a hepatitis B virus primary human hepatocyte infection model

Journal of hepatology, 2017, Vol.66 (1), p.S690-S691

2017

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Novel acyclic nucleotide analogues GS‐343074 and GS‐424044 demonstrate antiproliferative and pro‐apoptotic activity in canine neoplastic cell lines

Veterinary & comparative oncology, 2015-09, Vol.13 (3), p.246-254

2015

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Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.316-322

2016

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Development and characterization of a chronic hepatitis B murine model with a mutation in the START codon of an HBV polymerase

Physiological research, 2023, Vol.72 (1), p.37-47

2023

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Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Antimicrobial Agents and Chemotherapy, 2002-03, Vol.46 (3), p.716-723

2002

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Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment

Antimicrobial agents and chemotherapy, 2018-08, Vol.62 (8)

2018

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SAT-160 - Antiviral activity of GS-5801, a liver-targeted prodrug of a lysine demethylase 5 inhibitor, in a hepatitis B virus primary human hepatocyte infection model

Journal of hepatology, 2017, Vol.66 (1), p.S690-S691

2017

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Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells

Journal of viral hepatitis, 2003-01, Vol.10 (1), p.50-54

2003

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Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors

Antiviral research, 2002-04, Vol.54 (1), p.37-45

2002

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Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases α, δ, and ε

Antimicrobial Agents and Chemotherapy, 2002-05, Vol.46 (5), p.1610-1613

2002

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Activation of GS-7340 and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases

Antiviral research, 2007-06, Vol.74 (3), p.A57-A57

2007

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The Substrate Activity of (S)-9-[3-Hydroxy-(2-phosphonomethoxy)Propyl]Adenine Diphosphate toward DNA Polymerases α, δ and ε

Antiviral chemistry & chemotherapy, 2004, Vol.15 (1), p.23-33

2004

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Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases alpha , delta , and [varepsilon]

Antimicrobial agents and chemotherapy, 2002-05, Vol.46 (5), p.1610-1613

2002

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9-[2-(phosphonomethoxy)ethyl]adenine diphosphate (PMEApp) as a substrate toward replicative DNA polymerases α, δ, ε, and ε

Biochemical pharmacology, 1999-08, Vol.58 (3), p.487-492

1999

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Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε

Collection of Czechoslovak chemical communications, 2001, Vol.66 (11), p.1698-1706

2001

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Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization

Collection of Czechoslovak chemical communications, 1998, Vol.63 (5), p.723-731

1998

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Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases

Collection of Czechoslovak chemical communications, 1996, Vol.61 (s1), p.188-191

1996

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Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148

Bioorganic & medicinal chemistry, 2010-05, Vol.18 (10), p.3606-3617

2010

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P0645 : Non-synonymous single-nucleotide polymorphisms (SNPs) in TLR7 do not impact GS-9620 dependent TLR7 activation

Antiviral activity of GS-5801, a liver-targeted prodrug of a lysine demethylase 5 inhibitor, in a hepatitis B virus primary human hepatocyte infection model

Novel acyclic nucleotide analogues GS‐343074 and GS‐424044 demonstrate antiproliferative and pro‐apoptotic activity in canine neoplastic cell lines

Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors

Development and characterization of a chronic hepatitis B murine model with a mutation in the START codon of an HBV polymerase

Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment

SAT-160 - Antiviral activity of GS-5801, a liver-targeted prodrug of a lysine demethylase 5 inhibitor, in a hepatitis B virus primary human hepatocyte infection model

Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells

Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors

Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases α, δ, and ε

Activation of GS-7340 and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases

The Substrate Activity of (S)-9-[3-Hydroxy-(2-phosphonomethoxy)Propyl]Adenine Diphosphate toward DNA Polymerases α, δ and ε

Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases alpha , delta , and [varepsilon]

9-[2-(phosphonomethoxy)ethyl]adenine diphosphate (PMEApp) as a substrate toward replicative DNA polymerases α, δ, ε, and ε

Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε

Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization

Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases

Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148

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